 Derby University of the UK proudly announced their former student and academic product's ascendancy to Malawi's vice presidency on its university website on 13 April 2012.Before entering politics, Kachali was Second Vice-President for the Malawi Chamber of Commerce and Industry and he has been a businessman for years running various enterprises based in Mzuzu and large farming enterprise in Mzimba, his home district.Kachali is a well known Philanthropist assisting many people in education, start-up business capitals and Religious work

Kachali was Treasurer General for the United Democratic Front (UDF) from 2002 to 2004.