 His first wife, a pious and sickly woman, died in December 1642, leaving him a son and two daughters.By her deathbed suggestion Angier, a year later, married Margaret Mosley, of Ancoats, whose family were of great local consideration, and held the lordship of the manor of Manchester.They were married in 1643 'very publicly in Manchester church, in the heat of the wars, which was noticed as an act of faith in them both.'