 Milford Township is bordered by Jefferson Township to the northwest, Somerset Township to the northeast, Black Township to the southeast, Upper Turkeyfoot Township to the southwest, and Middlecreek Township to the west.Pennsylvania Route 281 passes through Milford Township, generally running northeast from New Lexington in Middlecreek Township, passing through New Centerville and bisecting Milford Township, and continuing through the southwestern part of Somerset Township on its way to the borough of Somerset.From New Lexington to New Centerville, Pennsylvania Route 281 & Pennsylvania Route 653 form a concurrency; in New Centerville, Pennsylvania Route 653 splits off and runs southeast to the borough of Rockwood.