 Some of the biggest Pasco employers include Hanford nuclear facility, Burlington Northern, Lamb Weston, Boise Cascade, Tyson Foods, Energy Northwest, Fluor Hanford Inc., Bechtel National Inc., and Pacific Northwest National Laboratory currently managed by Battelle Memorial Institute

Pasco is served by the Pasco School District, Columbia Basin College, and Washington State University Tri-Cities.Pasco High School is the older of the city's two public high schools, and was the largest in the state before Chiawana was built.The city's second high school—Chiawana High School—opened in August 2009.