 In March 2019, Gillibrand and Colorado senator Cory Gardner introduced the John S. McCain Opioid Addiction and Prevention Act, a bill that would require doctors and other medical professionals to limit opioid prescriptions for the first treatment of acute pain to no more than a supply of seven days.Gillibrand stated that too many in her home state of New York and across the US had been affected by the opioid epidemic and they needed to be proactive in addressing the issue.In March 2018, along with Amy Klobuchar and Patty Murray, Gillibrand led a letter signed by all 22 female U.S. senators to Senate Majority Leader Mitch McConnell and Senate Minority Leader Chuck Schumer that called for changes to a 1995 statute that formed the present policy for addressing workplace misconduct complaints on Capitol Hill and specified their support for an update to the policy that would streamline the process of reporting sexual harassment in addition to granting staffers more resources in filing reports.