 In August 2011, Vázquez was heavily linked with a move to Italian side Palermo as a replacement for fellow Argentine Javier Pastore.The move, effective from January 2012, was confirmed on 1 September 2011 for a €4.53 million transfer fee.He officially joined the Palermo squad on 29 December 2011, then debuted on 8 January in a match against Napoli.