 Captive specimens were observed to consume one fish every 2 to 25 hours.Bigfin reef squids are, in turn, preyed upon by tuna, marlin, swordfish, and other predator fish and groundfish.Bigfin reef squids serve as hosts to the copepod ectoparasite "Doridicola similis" and the worm-like dicyemid endoparasites "Dicyema koshidai" and "Dicyema orientale".