 Andy Roddick and John Isner, who both lost in the quarterfinals, would become the last American men to reach the quarterfinals of a Grand Slam tournament until Sam Querrey reached the quarterfinals at the 2016 Wimbledon Championships, a span of 22 Grand Slams.This was also the last Grand Slam tournament for two-time Quarterfinalist and former World No.5 Fernando González and the last US Open appearance for 2003 Finalist and former World No.