 In recent years, HMCS has seen an increase in use as a food additive due to the negative reputation of HFCS, as well as the absence of fructose, which is the source of the concern about the health effects of high fructose corn syrup.High-maltose syrups produced from corn are gluten-free, but certain syrups produced from wheat or barley may contain small amounts of gluten.It is unclear whether this can have significant effects in celiac disease.