 Almost all of area of the district was included into Ostashkovsky Uyezd, with the exception of the southeast of the district which belonged to Rzhevsky Uyezd.In 1775, Tver Viceroyalty was formed from the lands which previously belonged to Moscow and Novgorod Governorates, and the area was transferred to Tver Viceroyalty, which in 1796 was transformed to Tver Governorate.On 12 July 1929, governorates and uyezds were abolished, and Selizharovsky District with the administrative center in the selo of Selizharovo was established.