 In collaboration with John Mekalanos, Adele H. Lehman Professor of Microbiology, Harvard Medical School, Boston, Faruque has contributed extensively to the recent understanding of the epidemiology, transmissibility and ecology of "Vibrio cholerae".Their work showed the genetic basis for the origin and evolution of new "Vibrio cholerae" strains with epidemic potential and the role of bacteriophages in this process.They characterised several novel filamentous phages (e.g., KSF-1, RS1 and TLC satellite phages) of "Vibrio cholerae", and contributed substantially to understanding the molecular mechanisms for transmission of these phages, and their role in "Vibrio cholerae" evolution.