 Isetsky District is 40 km south of the city of Tyumen, 260 km east of the city of Yekaterinburg, and 1,650 km east of Moscow.The area measures 60 km (north-south), 60 km (west-east); total area is 2751 km2 (about 0.003% of Tyumen Oblast).The district is bordered on the north by Tyumensky District and Yalutorovsky District, on the east by Uporovsky District, on the south and west by Shatrovsky District of Kurgan Oblast, and on the northwest by Tugulymsky District of Sverdlovsk Oblast.