 Langham inherited the baronetcy on the death of his father in 1671.He was elected a Fellow of the Royal Society in 1678.Langham married four times, his first wife being Mary Alston, the daughter of Sir Edward Alston, his second wife Elizabeth, the daughter of Ferdinando Hastings, 6th Earl of Huntingdon, his third wife Penelope, the daughter of John Holles, 2nd Earl of Clare and his fourth wife Dorothy, the daughter of John Pomeroy of Devon.