 In Wimpfen Vogtherr was with the peasant leader Wendel Hipler and also had contact with Götz von Berlichingen, which is how he got involved in the German Peasants' War.As colonel of Hegauer farmers, he was involved in mid 1524 until the end (in July 1525) where they failed siege of cell (Radolfzell) on Lake Constance there.He managed to escape and was several months later safely found in the reformation friendly Strasbourg, where he in 1526 settled with his family.