 In certain cases, a combination of x-ray and radium therapy was suggested.In many skin diseases, the ulcers would be treated with radium and the surrounding areas with x-rays so it would positively affect the lymphatic systems.After using radium in the surgical treatment of tuberculosis, researchers including Béla Augustin and A. de Szendeffy soon developed a treatment using radioactive metholated iodine, which was patented under the name "dioradin" (formed from "iodine and radium") in 1911.