 In 2014, Hochreiter's group used deep learning to detect off-target and toxic effects of environmental chemicals in nutrients, household products and drugs and won the "Tox21 Data Challenge" of NIH, FDA and NCATS.Significant additional impacts in image or object recognition were felt from 2011 to 2012.Although CNNs trained by backpropagation had been around for decades, and GPU implementations of NNs for years, including CNNs, fast implementations of CNNs with max-pooling on GPUs in the style of Ciresan and colleagues were needed to progress on computer vision.