 When Arechederra came to the Philippines one of his initial position was to become one of the four superintendent-commissaries appointed by the Holy Office of the Inquisition to assist Inquisition in the islands.During his time, Filipino natives or "Indios" were exempted from the Inquisition, for example, when a Spanish mestizo named Jacinta de Jesús was to be charged, she was acquitted by Arechederra by proposing herself as an "Indio".In 1724, he accelerated the Inquisition charges filed against Antoine Guigue, a French missionary based in Guangdong convicted of Jansenism.