 The city padded the loss of thousands of jobs by using its industrial infrastructure to lure non-steel making jobs, but population losses have continued throughout the start of the new century.Struthers is located on the banks of the Mahoning River about west of the border between Ohio and Pennsylvania at the intersection of Ohio State Route 616 and Ohio State Route 289.The larger part of the city is across the river from State Route 289 on the south side of the river.