 Evidence to support Rho(D) immune globulin after a spontaneous miscarriage is unclear.In the UK, Rho(D) immune globulin is recommended in Rh-negative women after 12 weeks gestational age and before 12 weeks gestational age in those who need surgery or medication to complete the miscarriage.No treatment is necessary for a diagnosis of complete miscarriage (so long as ectopic pregnancy is ruled out).