 In March 2015, the Borough Council selected Kathy Merkh to fill the vacant seat of Deputy Mayor Jeff Fitzpatrick, who had submitted his resignation from office the previous month.Gary Miller was chosen to fill the vacant position of deputy mayor.Medford Lakes is located in the 3rd Congressional District and is part of New Jersey's 8th state legislative district

As of March 23, 2011, there were a total of 3,033 registered voters in Medford Lakes, of which 749 (24.7% vs. 33.3% countywide) were registered as Democrats, 1,009 (33.3% vs. 23.9%) were registered as Republicans and 1,275 (42.0% vs. 42.8%) were registered as Unaffiliated.