 One of the last cultures, that of the Fort Ancient people, had a few villages such as Buffalo and Marmet that survived into the time of European exploration.Historic tribes such as the Huron, from the Great Lakes region, and the Conoy (also spelled "Conois" and "Kanawha") were driven out of the central valley by Iroquois' invading from their base in present-day western New York.Many of the Conoy by the early 17th century had resettled on the west side of the Chesapeake Bay and below the Potomac River.