 Interstate 81 passes through Pittston Township.I-81 does not enter major metropolitan areas; it instead serves smaller cities such as Roanoke and Winchester, Virginia; Hagerstown, Maryland; Harrisburg, Wilkes-Barre and Scranton, Pennsylvania; and Binghamton and Syracuse, New York.After passing through Watertown, New York, Interstate 81 crosses the St. Lawrence Seaway to meet Highway 401 in Canada.