 She showed that stem cells lose their regenerative potential when grown in traditional plastic dishes and overcame this limitation by fabricating bioengineered microenvironments that mimic crucial stem cell niche and tissue properties.She
has applied this approach to identify molecules that rejuvenate the function of
the aged stem cell population and enhance muscle regeneration.Blau showed that telomere dysfunction in conjunction with dystrophin deficiency plays a central role in the skeletal muscle wasting and fatal cardiomyopathy characteristic of Duchenne muscular dystrophy.