 When he takes the pills, he becomes totally calm.Brian is initially upset about this, but when Meg mentions the creative benefits of it, he decides to try it himself, and becomes hyperactive in contrast to Stewie's calmness.In a creative frenzy, he conceives of a multimedia science fantasy franchise called "Space Shire 7"; to flesh out the idea, he writes a 2000 page treatment and creates a diorama of the universe and characters.