 One study found that [SEM]/[AVS] was a good predictor of toxic effects in laboratory exposures to field-contaminated sites.However, a re-analysis by other investigators suggested that [SEM]/[AVS] was neither a more sensitive predictor of toxic effects nor a more efficient one than simply measuring metals concentration per sediment dry weight.In addition, in Flemish rivers polluted with metals, AVS concentration had little to no effect on the accumulation of metals in benthic organisms (though no measurements of toxicity were done).