 Lefranc produced portraits, figures, florals, still lifes and landscapes in a variety of compositions.Her media included oil, watercolor, gouache, pastel, drawing, etching and monotypes.At age eighteen, she received accolades from Alfred Stieglitz and, in November 1928, aged twenty-two, received rave reviews in La Revue Moderne, when her works "Dancer" and "Mme M. en Pyjama" were shown in Paris.