 For example, they are found in 90% of parosteal osteosarcomas.Neochromosomes from well- and de-differentiated liposarcoma have been studied at high resolution by isolation (using flow sorting) and sequencing, as well as microscopy.They consist of hundreds of fragments of DNA, often derived from multiple normal chromosomes, stitched together randomly, and contain high levels of DNA amplification (~30-60 copies of some genes).