 During his first major league start on April 10, 2016, Wolters got his first career hit when he singled against James Shields.In the same game Wolters walked and scored a run for the first time in the big leagues.Wolters hit his first career homerun on June 25, 2016 against Shelby Miller of the Arizona Diamondbacks in the bottom of the 6th inning, scoring Brandon Barnes.