 In a review of "Detroit vs. Everybody" for "Rolling Stone", writer Kory Grow outlined that the song features "Several generations of the Motor City's most vital rhymers [revisiting] the struggle they rose above to break out of their hometown while still defending it", with lead artist Eminem reminiscing about his "pre-megastar days".The song has been described as "a rap rally cry for the Motor City", seeing the artists "defending [the city] against haters".The title of the song is taken from a clothing line founded by Detroit native Tommey Walker.