 Because PBCV-1 does not have an RNA polymerase gene, its DNA and viral-associated proteins move to the nucleus where transcription begins 5–10 minutes post infection.This rapid transcription is attributed to some component facilitating this transfer or viral DNA to the nucleus.This component is assumed to be a product of the "PBCV-a443r" gene, which obtains structures resembling proteins involved in nuclear trafficking in mammalian cells.