 All applications are examined and discussed by a Medical Review Committee, composed of individuals with expertise in various aspects of thalassemia research and treatment.Among the many areas in which the Foundation has supported research are the mechanisms of iron regulation, gene editing, and gene therapy as potential curative approaches to thalassemia; vector development; nutritional requirements in thalassemia; strategies for improving adherence to thalassemia treatments; fertility and pregnancy in thalassemia; cardiac issues in thalassemia; pulmonary hypertension; fetal hemoglobin production; and approaches to iron chelation therapy.Published medical research funded in whole or in part by the Foundation includes