 In 2009, Gaunt's group reported a copper catalyzed "meta"-selective C–H arylation reaction on anilide derivatives.Despite the intrinsic "ortho-/para-" selectivity of the amido group, the arylation occurs exclusively on the "meta" position on a variety of anilide substrates.Remarkably, the regioselectivity is totally different from the earlier reported Pd catalyzed C-H functionalizations, where the amido group serve as a powerful "ortho"-directing group.