 In 2016, the hospital publishes 651 scientific journals and conducted 455 clinical trials.The hospital is affiliated with University of Pavia, Faculty of Medicine, where every year, hundreds of medical students from the University perform clinical rotations during their clinical years.The hospital's foundation was first laid on 29 June 1449, and it was built at the request of Dominic of Catalonia, a Dominican friar with the full support by the secular and ecclesiastical authority.