 "Rise of the Dragon" is set around the middle of the 21st century and also features a protagonist named Blade, though this Blade is an ex-police officer and private investigator.In "Rise of the Dragon", a crime syndicate has developed a new drug called MTZ which mutates its users, with a criminal boss even using the drug to punish an underling for a failure by mutating him.The syndicate plans to release MTZ into the city's water supply with the intention of mutating the population.