 In 1538, in the nearby town of Villeneuve-Loubet, through the mediation of Pope Paul III, the two monarchs concluded a ten years' truce.In 1543, Nice was attacked by the united Franco-Ottoman forces of Francis I and Barbarossa Hayreddin Pasha, in the Siege of Nice; though the inhabitants repulsed the assault which followed the terrible bombardment, they were ultimately compelled to surrender, and Barbarossa was allowed to pillage the city and to carry off 2,500 captives.Pestilence appeared again in 1550 and 1580.