 Withdrawal bleeding can be induced monthly, like menstruation, or less often, usually every three months, if the patient desires.Estrogen therapy does not make a woman with nonfunctional ovaries fertile, but it plays an important role in assisted reproduction; the health of the uterus must be maintained with estrogen if an eligible woman with Turner Syndrome wishes to use IVF (using donated oocytes).Especially in mosaic cases of Turner syndrome that contains Y-chromosome (e.g.