 8 was then deselenated to form 9 (E-9 and Z-9), lastly leading to the formation of (-) domoic acid.The effects of domoic acid have been attributed to several mechanisms, but the one of concern is through glutamate receptors.Domoic acid is an excitatory amino acid analogue of glutamate; a neurotransmitter in the brain that activates glutamate receptors.