 In 2007 one analysis based on comparisons of RNA and another based mainly on comparison of spicules concluded that demosponges and glass sponges are more closely related to each other than either is to calcareous sponges, which in turn are more closely related to Eumetazoa.Other anatomical and biochemical evidence links the Eumetazoa with Homoscleromorpha, a sub-group of demosponges.A comparison in 2007 of nuclear DNA, excluding glass sponges and comb jellies, concluded that