 Venice quickly became the center of typographic and printing activity.Significant contributions came from Nicolas Jenson, Francesco Griffo, Aldus Manutius, and other printers of late 15th-century Europe.Gutenberg's movable type printing system offered a number of advantages over previous movable types The lead-antimony-tin alloy used by Gutenberg had half the melting temperature of bronze, making it easier to cast the type and aided the use of reusable metal matrix molds instead of the expendable sand and clay molds.