 His grandfather, Ed, also was home plate umpire in 1965 for Dave Morehead's no hitter, and his father Paul was third-base umpire for Charlie Lea's 1981 no-hitter.Runge served as home plate umpire for White Sox pitcher, Philip Humber's perfect game on April 21, 2012, at Safeco Field, and the combined no-hitter of Seattle Mariners pitcher Kevin Millwood and five relievers on June 8, 2012, also at Safeco Field, becoming the 10th Major League umpire to call balls and strikes for multiple no-hitters in the same season.He was the third-base umpire for the perfect game thrown by San Francisco Giants pitcher, Matt Cain, on June 13, 2012, at AT&T Park.