 O'Driscoll served as an officer in such Chicago-based organizations as the Sarah Siddons Society, the Ways and Means Committee of Chicago's Junior League, and the Women's Board of the Chicago Boys' Clubs; she was also treasurer of the World's Adoption International Fund.In the 1980s and 1990s, she was a guest speaker at numerous movie-nostalgia conventions.The Appletons started a horse stud farm, Bridlewood, in Ocala, Florida.