 Throughout June 1506 he raided the Dodecanese Islands before sailing back to the West Mediterranean with a fleet of 22 ships (including 3 large galleys and 11 fustas) where he landed on Sicily and assaulted the coastal settlements.There he was confronted by the forces of the Viceroy of Sicily who was an ally of Spain.In September 1506 Kemal Reis confronted a Spanish fleet for defending Djerba and captured a Spanish galley during combat.