 State Route 788 was established in 1939.Originally, the route ran from its intersection with Fairgreens Road northeast of Jackson to its current northern terminus at what was then known as State Route 75 (now State Route 93) west of Wellston.At the time, the current State Route 788 southwest of Fairgreens Road, and Fairgreens Road heading east from State Route 788, was a part of State Route 124.