"Galatino was born at Galatina, in Apulia.He received the habit as early as 1480, studied Oriental languages in Rome and was appointed lector at the convent of Ara Coeli; he also held the office of provincial in the province of Bari, and that of penitentiary under Leo X.

Galatino wrote his chief work "De Arcanis Catholicae Veritatis", at the request of the pope, the emperor, and other dignitaries, in 1516, at which time, owing mainly to John Reuchlin's "Augenspiegel", the famous controversy on the authority of the Jewish writings was assuming a very high-profile.