 NY 154 began at the intersection of US 4 (Vandenburgh Avenue) and Campbell Avenue in southern Troy.The route headed to the northeast, running alongside Wynants Kill as it followed Campbell Avenue through the residential southern portion of Troy.The route and the river crossed paths after , with Wynants Kill proceeding southeastward toward the hamlet of Wynantskill and NY 154 continuing northeastward to a junction with Spring Avenue, a street linking NY 154 to the downtown district.