 The route becomes parallel to the US 222 freeway located to the southeast and reaches direct ramps to and from the southbound lanes of US 222.Access to and from the northbound lanes is provided by Jake Landis Road, which passes under US 222 and connects to Butter Road, which provides access to the ramps.The route heads through wooded areas and passes over Lititz Run before it comes to the eastern terminus of PA 722 near the community of Oregon.