 Theca cells are stimulated by luteinizing hormone (LH), with signaling originating in the hypothalamus of the brain.Gonadotropin releasing hormone (GnRH) is released by projections of the hypothalamus into the anterior pituitary gland.Gonadotrophs are stimulated to produce follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are released into the bloodstream to act upon the ovaries.