 PA 272 followed US 222 through Lancaster and ran along the former alignment of US 222 between Lancaster and Adamstown.In 2006, the intersection at the northern terminus was converted to an interchange following the extension of the US 222 freeway from Adamstown to the Reading area.PA 272 is mostly in Lancaster County, except for about a mile at the northern terminus where it enters Berks County and the southernmost part of the route, which is in Chester County.