 The most common cause of myocardial rupture is a recent myocardial infarction, with the rupture typically occurring three to five days after infarction.Other causes of rupture include cardiac trauma, endocarditis (infection of the heart), cardiac tumors, infiltrative diseases of the heart, and aortic dissection.Risk factors for rupture after an acute myocardial infarction include female gender, advanced age of the individual, first ischemic event, and a low body mass index.