 In Rome Sorzano was acquainted not only with Cardinal Bembo, but also with Cardinal Reginald Pole and Vittoria Colonna, members of the circle of "spirituali" at Viterbo.All of these people were suspected of heresy and were being watched by the Roman Inquisition, whose head was Cardinal Gian Pietro Carafa.In the 1540s, the Inquisitor of Como and Bergamo was Fra Michele Ghislieri, O.P., whose attention was drawn to Sorzano by complaints from both civil and religious authorities.