 ‘Maine Coon PKD’ thus appears to represent a form of juvenile nephropathy other than AD-PKD.The presence of renal cysts in the absence of other changes, does not appear to negatively impact the patients' quality of life, as those for which follow-up was available were reported alive and well in adulthood.Although the exact nature and clinical relevance of renal cysts in Maine Coons are currently unknown, screening is still recommended for pre-breeding assessment.