 In 1557, Charles retired to the Monastery of Yuste in Extremadura and there died a year later.Charles was born on 24 February 1500 at the Prinsenhof in the Flemish city of Ghent, part of the Habsburg Netherlands in the Holy Roman Empire.He was the eldest son of Philip the Handsome of the Austrian House of Habsburg (son of Maximilian I of Austria and Mary of Burgundy) and Joanna the Mad of the Spanish House of Trastámara (daughter of Ferdinand of Aragon and Isabella of Castile).