 He openly neglected his wife, Maria of Portugal, and indulged a scandalous passion for Eleanor of Guzman, who bore him ten children.Infected by the Black Death during the 1349–1350 siege of Gibraltar, Alfonso died in the night of 25–26 March 1350 (some sources put the date wrongfully at 27 March).Alfonso XI first married Constanza Manuel in 1325, but had the union annulled two years later.