 The sinus space is criss-crossed by the pseudopods of macrophages, which act to trap foreign particles and filter the lymph.The medullary sinuses converge at the hilum and lymph then leaves the lymph node via the "efferent lymphatic vessel" towards either a more central lymph node or ultimately for drainage into a central venous subclavian blood vessel.Lymph node enlargement or swelling is known as lymphadenopathy.