 Until the 1950s, the Dene Thá lived a semi-nomadic lifestyle and hunted in their traditional territory, which included land in the northwestern corner of Alberta, the southern Northwest Territories, and the northeastern corner of British Columbia.Today, many live in permanent settlements in and around Bushe River, Meander River, and Chateh.The Dene Thá First Nation signed Treaty 8 in 1900.

 the First Nations registered population was 2871 with 2017 members living on reserves or crown land and 854 members living off reserve.