 The road passes through Dysart before turning north-northeast and running through Tippletown and Dean.The route crosses into Reade Township and becomes Glendale Valley Boulevard, running through more forests with sparse fields and residences and turning northwest through Frugality before heading north again.In Van Ormer, PA 53 intersects the southern terminus of PA 253 and continues north-northwest through more rural areas, passing through Fallen Timber.