 (see also Dynamic kinetic resolution)

The chirality of the diamine ligand made it possible for the BINAP/diamine-Ru complex possible to reduce simple ketones enantioselectively.Due to the steric hindrance between the BINAP ligand and the large substituent group on ketone (phenyl ring on the scheme below), the less steric hindered transition state is favored as expected.The simple ketones include aromatic, heteroaromatic, and alkenyl ketones.