 Later, the 1481 Papal Bull "Aeterni regis" granted all lands south of the Canary Islands to Portugal, while in May 1493 the Spanish-born Pope Alexander VI decreed in the Bull "Inter caetera" that all lands west of a meridian only 100 leagues west of the Cape Verde Islands should belong to Spain while new lands discovered east of that line would belong to Portugal.These arrangements were later precised with the 1494 Treaty of Tordesillas.The Dominicans and Jesuits, notably Francis Xavier in Asia, were particularly active in this endeavour.