 "sec"-BuLi is employed for deprotonations of particularly weak carbon acids where the more conventional reagent "n"-BuLi is unsatisfactory.It is, however, so basic that its use requires greater care than for "n"-BuLi.For example diethyl ether is attacked by "sec"-BuLi at room temperature in minutes, whereas ether solutions of "n"-BuLi are stable.