 She died, a widow, in 1522 on her way home to Rome, coming back from a pilgrimage at Loreto Sanctuary.Little is known about Agnese's childhood, whose mother died in 1472 when she was only two years old.Her father died in 1482, when Agnese was twelve, after which she was entrusted to the care of her paternal uncle, Ottaviano Ubaldini della Carda, along with her elder sisters.