 Cardinal Giorgio Fieschi, Bishop of Ostia, died on 8 October 1461; the vacancy was immediately filled by Cardinal Guillaume d'Estouteville, who opted for the office of Bishop of Ostia at the papal Consistory of 26 October, leaving a vacancy in the diocese of Porto.On the same day, Cardinal Juan Carvajal opted for Porto and Santa Rufina.From then on, he lived in Rome, in a house near S. Marcello.