 AEME is also used in scientific research for the manufacture of phenyltropane analogues such as troparil, dichloropane, iometopane, and CFT.Methylecgonidine could also theoretically be used to produce cocaine and so may be a controlled substance in some countries.Methylecgonidine can be synthesized non pyrolytically from cocaine via hydrolysis/dehydration followed by esterification with methanol.