 A barrier cabinet using RABS design and control, is below the isolator in its ability to assure sterility assurance and containment, but far better than the traditional laminar air flow hood or "open process" designs that are progressively being phased-out by the industries.In particular, a RABS that operates only in closed-door mode after the equipment setup and sporadical disinfection is performed, is commonly used now and provides substantial risk mitigation.These "closed RABS" require all processing interventions to be done using gauntlet gloves attached to the RABS walls.