 The route intersects many roads including U.S. Route 1 (US 1) north of Media, PA 3 in Newtown Square, US 30 in Paoli, and US 202 in Tredyffrin Township.The southernmost part of PA 252 was originally built as part of the Providence Road in 1684.PA 252 was designated by 1928 to run from PA 320 north of Chester north to US 122/PA 52 (now US 202) in King of Prussia.