 There have been multiple studies to find a replacement oxidant that is less expensive than [PtIVCl6]2− or a method to regenerate [PtIVCl6]2−.It would be most advantageous to develop an electron train which would use oxygen as the ultimate oxidant.It is important that the oxidant preferentially oxidizes the PtII-CH2R species over the initial PtII species since PtIV complexes will not electrophilically activate a C-H bond of the alkane (although PtIV complexes electrophilically substitute hydrogens in aromatics - see refs.