 He accompanied Henry FitzAlan, 19th Earl of Arundel into Italy as interpreter, and returned with him to England.Carew then entered on practice in the court of arches, and ultimately became master in chancery, a position which he held for many years, being knighted on 23 July 1603, before the coronation of James I.His wife was Alice, eldest daughter of Sir John Rivers, knight, Lord Mayor of London, and widow of one Ingpenny; by her Carew had numerous children.