 In December, the regiment left for Henderson, Kentucky.It camped at Calhoun, Kentucky, until February 1862, when it moved to Fort Henry, Tennessee, then to Fort Donelson, Tennessee, where it participated in the siege of the fort, taking heavy casualties there.The regiment was engaged both days, April 6–7, 1862, at the Battle of Shiloh, where it suffered 33 killed and 177 wounded.