 Several papers have shown the relationship between the thickness of the choroidal, Sattler's and Haller's layer between healthy individuals and in people with age-related macular degeneration (AMD).The studies showed significant reduction of layer thickness in relation to the progression of AMD, which may be important in the understanding of choriopathy in the pathophysiology of AMD.However, also strong variations even throughout the diurnal cycle, as well as the influence of optical stimuli during eye-growth indicate that the complex function of this tissue is not entirely understood and might be one of the reasons for the frequently found separation in vascular size between Haller's and Sattler's layer.