 He emigrated to England in 1928, where he served as the rosh yeshiva of the Etz Chaim Yeshiva in the East End of London, working for many years alongside his distinguished colleague Rabbi Nachman Shlomo Greenspan.His wife Soroh Leah Rotman died in 1934, shortly after the engagement of their daughter Leiba to Rabbi Leib Gurwicz.For many years, Rabbi Lopian had wanted to make his home in the Land of Israel, and spoke a great deal about the Vilna Gaon's intense yet unfulfilled desire to live there.