 Because the unconjugated bilirubin is not water-soluble, one will not see an increase in bilirubin in the urine.Because there is no problem with the liver or bile systems, this excess unconjugated bilirubin will go through all of the normal processing mechanisms that occur (e.g., conjugation, excretion in bile, metabolism to urobilinogen, reabsorption) and will show up as an increase in urine urobilinogen.This difference between increased urine bilirubin and increased urine urobilinogen helps to distinguish between various disorders in those systems.