 Abetalipoproteinemia

Abetalipoproteinemia is a disorder that interferes with the normal absorption of fat and fat-soluble vitamins from food.It is caused by a mutation in microsomal triglyceride transfer protein resulting in deficiencies in the apolipoproteins B-48 and B-100, which are used in the synthesis and exportation of chylomicrons and VLDL respectively.