 Andrew Ganigan proved to be one of Argüello's toughest challenges as he dropped Argüello in the second round, but ultimately the defending champion prevailed by stopping Ganigan in the fifth.Arguello successfully defended his lightweight title four times.After defeating James 'Bubba' Busceme by sixth round stoppage, Argüello decided to move up in weight class again, and on November 12, 1982, he tried to become the first world champion in 4 different categories, meeting the heavier and future Hall-of-Famer Aaron Pryor, in what was billed as "The Battle of the Champions" in Miami, Florida.