 Bishop János Vitéz (alias Johann Vitíz von Zredna, 1445-1465) was one of the most distinguished and active promoters of Humanism in Hungary.The political dissolution following the Battle of Mohács in 1526 and the spread of Protestantism caused the rapid decline of the diocese.After the death of György Martinuzzi (1535–1551), the greatest of the bishops of Várad and the advisor of King János Szapolyai and Queen Isabella, the see deteriorated.