 Jane married William Hough (c.1527 – 1585), of Leighton in Wirrall, Cheshire, around 1550.William Hough was the son of Richard Hough (1505 – 1573/4) who was employed by Thomas Cromwell from 1534 to 1540 as his agent in Chester.It is unknown what role Thomas and Gregory Cromwell played in her life.