 He died in London and is buried in the Old Jewish Cemetery in Mile End Road.Nieto was a powerful controversialist.In his "Matteh Dan", or "Kuzari Heleq Sheni" (London, 1714), written in Hebrew and Spanish on the model of the Kuzari of Judah ha-Levi, he defended the Oral Torah against the Karaites, and showed that the disagreements in the Talmud lay not in essential laws but in minor matters.