 Immediately prior to the events transpiring in "Dune" (1965), she is kidnapped by the Baron Vladimir Harkonnen, who uses the threat of her extended torture to subvert Yueh's Suk Imperial Conditioning (which normally prohibits him from doing harm) and coerce him to betray Duke Leto Atreides.Yueh gives in to the Baron's demands, but twists the letter of his orders and tries to kill Harkonnen with the unwitting help of Duke Leto, an attempt that ultimately fails.Yueh discovers (as he suspected) that Wanna had already been killed (presumably in 10,186 A.G., per the "Dictionary of Muad'Dib" by the Princess Irulan, as referenced via epigraph in "Dune"), and is killed himself by the Baron's twisted Mentat, Piter De Vries.