 Mendel created a practical guide to breeding and this method has successfully been applied to select for some of the first model organisms of other genus and species such as Guinea pigs, "Drosophila" (fruit fly), mice, and viruses like the tobacco mosaic virus.The fruit fly "Drosophila melanogaster" made the jump from nature to laboratory animal in 1901.At Harvard University, Charles W. Woodworth suggested to William E. Castle that "Drosophila" might be used for genetical work.