 SR 338 begins at an intersection with US 441/US 411/SR 35/SR 71 in Seymour.It winds its way northeast as Boyds Creek Highway to pass through Boyds Creek before entering Sevierville and coming to an intersection with SR 66.SR 338 turns south and becomes concurrent with SR 66 to pass through a business district before leaving SR 66 and turning northeast onto Douglas Dam Road and leaving Sevierville.