 He thinks that the technologies will develop in the direction of self-regulating systems which will penetrate many spheres starting from medicine to food production.With respect to possible dramatic changes of the human organism he argues that they may rise unprecedented ethical issues and seriously damage many vital aspects of our life including family relations, gender, and morals.Grinin insists that the two-stage scheme of the state macroevolution (Early State – Mature State) proposed by Henri Claessen and Peter Skalnik is not sufficient, and suggests that it should be modified as "Early State – Developed State – Mature State", emphasizing that the differences between developed and early states are no less pronounced than the ones between the former and the mature states.