 In 2010, Han took on the titular character in MBC's 49th anniversary project "Dong Yi", The series became a hit during its run both domestically and across Asia.Han won several acting awards for her portrayal of Choi Suk-bin, including the "Daesang" (Grand Prize) award at MBC Drama Awards and the coveted Best Actress award at Baeksang Arts Awards.In 2011, Han played a blind telemarketer opposite So Ji-sub's ex-boxer in the melodrama film "Always".