 Although exact figures are difficult to obtain, some have estimated that one million fetal cows are sacrificed each year to obtain the world's supply of fetal bovine serum, used to grow cultured cells.The testing of cosmetic products directly onto an animal can be minimized or eliminated by the use of "in Vitro" cell growth and development.This can be generalized as the growth of cells outside of the body and tested on without causing harm or pain on the test subject.