 As the dedication to an eastern saint suggests, this places it in a period of strong Byzantine influence in Rome.It was rebuilt under Pope Nicholas V, had its long-held titular church status suppressed by Pope Sixtus V, was renovated by Francesco Barberini in 1643, and rebuilt and given to the Society of the Sacred Heart of Jesus by Pope Clement XI and his architect Carlo Fontana in 1703–1705.Its titulus was reestablished on 2 December 1959 by Pope John XXIII, with William Theodore Heard (1959–1970, pro hac vice presbyterial titular 1970–1973).