 She accomplished this by developing tumors that expressed a gene commonly found in skin cancer cells, HRasD12V.Her research demonstrated that the cancerous stem cells lacking the TGF-β signal proliferate more quickly but are sensitive to antiproliferative drugs.This is unlike the cancerous stem cells that received the TGF-β signal, which proliferated at a slower rate than those lacking the TGF-β signal but were resistant to antiproliferative drugs.