 SEURAT-1 will develop knowledge and technology building blocks required for the development of solutions for the replacement of current repeated dose systemic toxicity testing "in vivo" used for the assessment of human safety.SEURAT-1 is composed of six research projects, which started on January 1, 2011 and will run for five years.These projects will closely cooperate with a common goal and combine the research efforts of over 70 European universities, public research institutes and companies.