 He was overthrown as regent in 1843 by Ramón María Narváez, a moderate, who was in turn perceived as too reactionary.Another Carlist uprising, the Matiners' War, was launched in 1846 in Catalonia, but it was poorly organized and suppressed by 1849.Isabella II of Spain took a more active role in government after coming of age, but she was immensely unpopular throughout her reign (1833–68).