 Rising inflation, financially draining wars in Europe, the ongoing aftermath of the expulsion of the Jews and Moors from Spain, and Spain's growing dependency on the silver imports, combined to cause several bankruptcies that caused economic crisis in the country, especially in heavily burdened Castile.The great plague of 1596–1602 killed 600,000 to 700,000 people, or about 10% of the population.Altogether more than 1,250,000 deaths resulted from the extreme incidence of plague in 17th-century Spain.