TS.C.6.1 Future global burdens of climate-sensitive diseases and conditions will depend on emissions and adaptation pathways and the efficacy of public health systems, interventions and sanitation . Projections under mid-range emissions scenarios show an additional 250,000 deaths per year by 2050  due to malaria, heat, childhood undernutrition and diarrhoea . Overall, more than half of this excess mortality is projected for Africa. Mortality and morbidity will continue to escalate as exposures become more frequent and intense, putting additional strain on health and economic systems , reducing capacity to respond, particularly in resource- poor regions. Vulnerable groups include young children , the elderly , pregnant women, Indigenous Peoples, those with pre-existing diseases, physical labourers and those in low socioeconomic conditions . 
IPCC
Climate Change 2022: Impacts, Adaptation and Vulnerability
IPCC Report