TS.C.4.2 Projected cryosphere changes will negatively impact water security and livelihoods, with higher severity of risks at higher levels of global warming . Glacier mass loss, permafrost thaw and decline in snow cover are projected to continue beyond the 21st century . Many low- elevation and small glaciers around the world will lose most of their total mass at 1.5°C warming . Glaciers are likely to disappear by nearly 50% in High Mountain Asia and about 70% in Central and Western Asia by the end of the 21st century under the medium warming scenario. Glacier lake outburst flood will threaten the security of local and downstream communities in High Mountain Asia . By 2100, annual runoff in one-third of the 56 large-scale glacierised catchments are projected to decline by over 10%, with the most significant reductions in Central Asia and the Andes . Cryosphere related changes in floods, landslides and water availability have the potential to lead to severe consequences for people, infrastructure and the economy in most mountain regions . 
IPCC
Climate Change 2022: Impacts, Adaptation and Vulnerability
IPCC Report