2016). While there is strong association between ambient temperature and cardiovascular events globally, there are complex interactions and modulators of individual response . Further, some CVD morbidity sub-groups such as myocardial infarction  and stroke hospitalisation display temperature sensitivity while others do not . Although older adults have inherent sensitivities to temperature-related health impacts , children can also be affected by extreme heat . Cardiovascular capacity or health is also a critical determinant of individual health outcomes . Medications to treat CVDs, such as diuretics and beta-blockers, may impair resilience to heat stress . Other mediating factors in the causal pathway range from alcohol consumption  and obesity  to pre-existing conditions, such as diabetes and hyperlipidaemia, and urban characteristics .
IPCC
Climate Change 2022: Impacts, Adaptation and Vulnerability
IPCC Report