For most Representative Key Risks , potentially global and systemically pervasive risks become severe in the case of high warming, combined with high exposure/vulnerability, low adaptation, or both . Under these conditions, there would be severe and pervasive risks to critical infrastructure  and to human health from heat-related mortality, to low-lying coastal areas, aggregate economic output, and livelihoods , of armed conflict , and to various aspects of food security . Severe risks interact through cascading effects, potentially causing amplification of RKRs over the course of this century . 
IPCC
Climate Change 2022: Impacts, Adaptation and Vulnerability
IPCC Report