Changes in range distribution will interact with detailed local knowledge and Indigenous knowledge needed to harvest and use medicinal plants. Northward range shifts, for example, may mean certain plants still exist, but not where they have traditionally been important as medicine, and possibly moving suitable ranges outside of areas where plants species have sufficient protection . Climate-induced phenological changes are already observed as a threat to some species . Other major climate-induced impacts on medicinal plants will be via the phytochemical content and pharmacological properties of medical plants . Experimental trials have shown that drought stresses increase phytochemical content, either by decreasing biomass or increasing metabolites production  .
IPCC
Climate Change 2022: Impacts, Adaptation and Vulnerability
IPCC Report