Climate change is projected to significantly increase population exposure to heatwaves  and heat-related morbidity and mortality . Models suggest exposure increases 16 times under Representative Concentration Pathway 4.5 and 36 times under RCP8.5, with the impact of warming amplified under development pathways that do not foster sustainable development. Globally, the impact of projected climate change on temperature-related mortality is expected to be a net increase under RCP4.5 to RCP8.5, even with adaptation . Heat related cardiovascular disease mortality is projected to increase by the end of this century . Strong geographical differences in heat-related mortality are projected to emerge later this century, mainly driven by population growth and aging in regions with tropical and subtropical climates  .
IPCC
Climate Change 2022: Impacts, Adaptation and Vulnerability
IPCC Report