A patient undergoing chemotherapy for leukemia is admitted for pneumonia for which treatment with cefepime has been prescribed. A chest X-ray/CT scan shows an infiltrate with halo sign and crescentic meniscus. The lesion is peripheral and a transthoracic puncture is indicated for sampling. Pending definitive histologic and microbiologic results, what antimicrobial would you add to the treatment?
Direct response question. This is a patient undergoing chemotherapy with respiratory symptoms and the "halo sign" on X-ray, very suggestive of invasive pulmonary aspergillosis. Treatment is with voriconazole. Aspergillus is resistant to fluconazole, so it would not be a valid option.
Ganciclovir.
Caspofungin.
Fluconazole.
Piperacillin-tazobactam.
Voriconazole.
Aspergillus is resistant to fluconazole, so it would not be a valid option.
This is a patient undergoing chemotherapy with respiratory symptoms and the "halo sign" on X-ray, very suggestive of invasive pulmonary aspergillosis. Treatment is with voriconazole.