An 84-year-old man with chronic heart failure in functional grade II secondary to ischemic heart disease with severe non-revascularizable systolic dysfunction, stage 3 chronic kidney disease (glomerular filtration rate 45-50 mL/min) and permanent atrial fibrillation with heart rate >80 beats per minute. Which of the following drugs does NOT provide benefit to the patient according to the currently available evidence?
Ivabradine, in fact, is contraindicated in patients with atrial fibrillation. Initially (although evidence has recently emerged that qualifies this information) ivabradine was said to be selective over the sodium If current in the sinus node. If the patient is in AF, it makes no sense to act on the sinus node.
Ivabradine.
Angiotensin converting enzyme inhibitors.
Antialdosterone.
Beta-blockers.
Ivabradine, in fact, is contraindicated in patients with atrial fibrillation.