A 27-year-old black woman consults for the appearance of edema in the lower limbs, decreased diuresis, fever and a malar rash in butterfly wings of 20 days of evolution. Laboratory tests showed creatinine 3 mg/dl, leukopenia, hemoglobin 10.5 g/dl (normochromic normocytic), CRP 9 mg/dl and ESR 60 mm. Regarding the pathology presented by this patient, point out the correct answer:
Another question about SLE antibodies. Clinical case of SLE with renal involvement, in which positive double-stranded anti-DNA increases the risk of nephritis. As for the rest, anti-Sm are specific to SLE, ANA are detected in more than 90% of cases, and anti-centromere are typical of scleroderma.
The anti-Sm antibodies are not specific for this pathology.
Anti-centromere antibodies are detected in 90% of cases.
ANA (antinuclear antibodies) are detected in 50% of cases.
Anti-two-stranded or native anti-DNA correlates with the risk of nephritis.
anti-Sm are specific to SLE,
anti-centromere are typical of scleroderma.
ANA are detected in more than 90% of cases,
Clinical case of SLE with renal involvement, in which positive double-stranded anti-DNA increases the risk of nephritis.