| { | |
| "significant_genes": { | |
| "Variable": [ | |
| "HLA-B", | |
| "CD36", | |
| "KIR2DL3", | |
| "CYP2E1", | |
| "CTSW", | |
| "FAS", | |
| "IFNA8", | |
| "CARD16", | |
| "GAB2", | |
| "TXN", | |
| "ISG15", | |
| "JUN", | |
| "IL13RA1", | |
| "AKT1", | |
| "CARD11", | |
| "DNAJC10", | |
| "PIK3CB", | |
| "MAF", | |
| "LILRA6", | |
| "CXCL9", | |
| "OAS1", | |
| "MSRA", | |
| "IL36G", | |
| "CSF1", | |
| "HLA-DMB", | |
| "CCR6", | |
| "IL27", | |
| "IFNA2", | |
| "PIK3C3", | |
| "CCL2", | |
| "CD22", | |
| "GLB1", | |
| "IL2RA", | |
| "PDCD1LG2", | |
| "PANX1", | |
| "IRF9", | |
| "LCP1", | |
| "IKBKG", | |
| "CCL28", | |
| "IL4R", | |
| "LTB", | |
| "HSP90AA1", | |
| "SELENOS", | |
| "PIK3R5", | |
| "MAPK13", | |
| "NPC2", | |
| "IL36RN", | |
| "CD44", | |
| "IL1B", | |
| "CASP5", | |
| "ACKR3", | |
| "CXCL10", | |
| "IGFBP7", | |
| "CTSZ", | |
| "CCR2", | |
| "ITGB2", | |
| "IRF1", | |
| "IL34", | |
| "EIF2AK3", | |
| "CCRL2", | |
| "HLA-DPB1", | |
| "ANPEP", | |
| "CD68", | |
| "IL27RA", | |
| "ULK2", | |
| "BST2", | |
| "PSMB10", | |
| "LTA4H", | |
| "BDKRB1", | |
| "CD40LG", | |
| "HLX", | |
| "AKT3", | |
| "CBFB", | |
| "CCL23", | |
| "JAK1", | |
| "IL22RA2", | |
| "PSEN1", | |
| "PTK2B", | |
| "LTF", | |
| "DEFA4", | |
| "CHUK", | |
| "CD4", | |
| "MAP3K5", | |
| "TCIRG1", | |
| "CXCR3", | |
| "NLRC5", | |
| "IFNA6", | |
| "ZAP70", | |
| "CXCL12", | |
| "TGFB3", | |
| "RAB31", | |
| "JUNB", | |
| "IRF7", | |
| "TLN1", | |
| "BCL2L1", | |
| "IFI16", | |
| "CX3CR1", | |
| "MAP3K8", | |
| "TMEM140", | |
| "CXCL11", | |
| "PTGER2", | |
| "HLA-A", | |
| "BATF", | |
| "GSTM4", | |
| "CCL5", | |
| "IL31", | |
| "ATP6V0D1", | |
| "CCL25", | |
| "BNIP3", | |
| "ALOX15", | |
| "EIF3F", | |
| "GBA1LP", | |
| "CD3D", | |
| "IL10RA", | |
| "ACOX1", | |
| "IFITM1", | |
| "MT2A", | |
| "SMAD4", | |
| "ELANE", | |
| "CD84", | |
| "CD14", | |
| "MVP", | |
| "IKBKB", | |
| "NOTCH1", | |
| "IL32", | |
| "PLAU", | |
| "TLR3", | |
| "ACKR4", | |
| "APEX1", | |
| "LILRA3", | |
| "VCAM1", | |
| "PRKCQ", | |
| "OAS2", | |
| "AP1G1", | |
| "BDKRB2", | |
| "CD244", | |
| "TYROBP", | |
| "CASP10", | |
| "CBL", | |
| "BCR", | |
| "TNFSF18", | |
| "HSP90B1", | |
| "ALPK1", | |
| "RACK1", | |
| "IL10RB", | |
| "TYK2", | |
| "PXN", | |
| "HAMP", | |
| "KRAS", | |
| "GLA", | |
| "HERC5", | |
| "ITK", | |
| "NAE1", | |
| "IL12B", | |
| "PIK3R3", | |
| "LTBR", | |
| "WIPI1", | |
| "IDO1", | |
| "ETS1", | |
| "HPGD", | |
| "MS4A2", | |
| "CCL22", | |
| "BPI", | |
| "ATF6", | |
| "IL20", | |
| "IRF4", | |
| "CPA3", | |
| "EOMES", | |
| "IFIH1", | |
| "PLAUR", | |
| "IL13", | |
| "MAP3K7", | |
| "IL17C", | |
| "IFNK", | |
| "SP1", | |
| "CD80", | |
| "MAPK9", | |
| "IL7", | |
| "CXCL1", | |
| "GNLY", | |
| "STAT5A", | |
| "MS4A7", | |
| "FCGR2A", | |
| "HMGB1", | |
| "ITGB7", | |
| "CRP", | |
| "IL36B", | |
| "CSF2RA", | |
| "EGLN1", | |
| "AIF1", | |
| "IFI35", | |
| "PSAP", | |
| "MAP2K2", | |
| "NCF1", | |
| "OASL", | |
| "NTNG2", | |
| "RELA", | |
| "IL17F", | |
| "RNF135", | |
| "ITGAL", | |
| "TNFRSF1A", | |
| "KLRD1", | |
| "PDCD1", | |
| "IL16", | |
| "IL21R", | |
| "PRKCSH", | |
| "FCRL2", | |
| "FAM30A", | |
| "PRCP", | |
| "TRAF2", | |
| "HLA-E", | |
| "TIGIT", | |
| "LYN", | |
| "RIGI", | |
| "TMPRSS2", | |
| "MGAM", | |
| "HCST", | |
| "FCRL4", | |
| "CRK", | |
| "TNFRSF10B", | |
| "BCL6", | |
| "CASP8", | |
| "LCP2", | |
| "IL23R", | |
| "CCL26", | |
| "FPR1", | |
| "NDUFS8", | |
| "FCAR", | |
| "APOBEC3G", | |
| "CDK4", | |
| "TNFRSF4", | |
| "ERN1", | |
| "CCL13", | |
| "IL17D", | |
| "APOL6", | |
| "TRIM33", | |
| "ULK1", | |
| "SIRPA", | |
| "TNFSF9", | |
| "CTSL", | |
| "KDM6B", | |
| "MYD88", | |
| "AP1M1", | |
| "IL18RAP", | |
| "GZMH", | |
| "IL19", | |
| "IL13RA2", | |
| "ITGAE", | |
| "CCR5", | |
| "TLR4", | |
| "MEFV", | |
| "NCR3", | |
| "NOD2", | |
| "PDHB", | |
| "CD1E", | |
| "ATG4A", | |
| "AGT", | |
| "SOCS3", | |
| "RASGRP4", | |
| "ITPR3", | |
| "IL36A", | |
| "CXCL3", | |
| "HLA-DQB1", | |
| "CCR3", | |
| "AHR", | |
| "OS9", | |
| "PLEKHA1", | |
| "CD276", | |
| "IL6ST", | |
| "DIABLO", | |
| "CCL27", | |
| "MAP1LC3A", | |
| "DDOST", | |
| "MKNK1", | |
| "CD40", | |
| "GUCY1B1", | |
| "UBE2N", | |
| "STAT6", | |
| "MDFIC", | |
| "CR1", | |
| "CCL24", | |
| "CCL16", | |
| "IL1RN", | |
| "TNFSF13B", | |
| "PECAM1", | |
| "HLA-DPA1", | |
| "ACSL1", | |
| "CXCL2", | |
| "IL12RB1", | |
| "FURIN", | |
| "IFNAR2", | |
| "CUL1", | |
| "PTGER4", | |
| "CAP1", | |
| "PLCG1", | |
| "CD6", | |
| "MS4A1", | |
| "XCR1", | |
| "HLA-DOB", | |
| "CD3G", | |
| "C5", | |
| "IL37", | |
| "GBP4", | |
| "ATG7", | |
| "VRK3", | |
| "CD27", | |
| "CCL15", | |
| "FOXO1", | |
| "SOD1", | |
| "EIF2AK2", | |
| "MME", | |
| "LCK", | |
| "IL9", | |
| "TNFSF4", | |
| "PARP9", | |
| "FOS", | |
| "IFITM3", | |
| "ALOX5AP", | |
| "WAS", | |
| "REL", | |
| "PIK3CA", | |
| "STING1", | |
| "PRF1", | |
| "XBP1", | |
| "TXNIP", | |
| "TOLLIP", | |
| "CXCL16", | |
| "HLA-DMA", | |
| "CCR4", | |
| "GADD45B", | |
| "TNFRSF9", | |
| "IL10", | |
| "NFKB1", | |
| "GK", | |
| "CD38", | |
| "CTLA4", | |
| "IL9R", | |
| "APBB1IP", | |
| "KLRK1", | |
| "CFLAR", | |
| "CARD17P", | |
| "CGAS", | |
| "IL20RB", | |
| "CXCL17", | |
| "FPR2", | |
| "CDH1", | |
| "IL21", | |
| "PLIN4", | |
| "LRG1", | |
| "CXCL6", | |
| "S100A12", | |
| "TBK1", | |
| "IL17A", | |
| "IL5RA", | |
| "RUNX3", | |
| "TRIM22", | |
| "FYN", | |
| "TNFRSF18", | |
| "RAB7A", | |
| "IL1RAPL1", | |
| "PLCG2", | |
| "PRKCA", | |
| "MAPK8", | |
| "DDAH2", | |
| "IL17RB", | |
| "IL17RD", | |
| "ADGRE5", | |
| "MLKL", | |
| "PLAT", | |
| "IL6", | |
| "CXCL13", | |
| "IRAK1", | |
| "IL15", | |
| "JAK3", | |
| "IFI44", | |
| "PPIA", | |
| "CD79B", | |
| "IRF3", | |
| "ATG3", | |
| "PLEK", | |
| "TCF7", | |
| "RNF31", | |
| "ARRB2", | |
| "NFATC1", | |
| "CCL19", | |
| "SUGT1", | |
| "IL33", | |
| "IL12A", | |
| "NFE2L2", | |
| "MAP2K4", | |
| "IL7R", | |
| "PRKCD", | |
| "TLR2", | |
| "RPS6KA3", | |
| "STAT3", | |
| "STT3B", | |
| "TNF", | |
| "IL6R", | |
| "IL31RA", | |
| "KIR2DL1", | |
| "FCGRT", | |
| "NLRP3", | |
| "NRAS", | |
| "OAS3", | |
| "GPX7", | |
| "IL5", | |
| "ITGAM", | |
| "KLRC1", | |
| "IL22RA1", | |
| "AP1S2", | |
| "CXCL8", | |
| "ZBP1", | |
| "ACVR1", | |
| "CCL8", | |
| "SELE", | |
| "PIK3R6", | |
| "CXCR4", | |
| "MAPKAPK2", | |
| "IRAK4", | |
| "TRAM1", | |
| "IL20RA", | |
| "CD86", | |
| "LDHB", | |
| "LIF", | |
| "SLC11A1", | |
| "RIPK1", | |
| "CXCR6", | |
| "SPIB", | |
| "MAP3K3", | |
| "CCL18", | |
| "CSF3R", | |
| "TNFRSF25", | |
| "CASP4", | |
| "HCK", | |
| "VSIR", | |
| "PYCARD", | |
| "TRIM5", | |
| "CTSS", | |
| "NT5E", | |
| "TAP1", | |
| "LILRA5", | |
| "HDC", | |
| "CCR7", | |
| "ATP6AP2", | |
| "IFNL4", | |
| "CTSA", | |
| "CCNC", | |
| "LCN2", | |
| "IL23A", | |
| "ATF4", | |
| "IFNG", | |
| "JAML", | |
| "TCL1A", | |
| "IL18BP", | |
| "UBE2L6", | |
| "SOCS1", | |
| "DDX5", | |
| "PNOC", | |
| "VWF", | |
| "RASGRP1", | |
| "TLR6", | |
| "CXCR1", | |
| "GSK3B", | |
| "RPS6KB1", | |
| "CD8A", | |
| "IL18R1", | |
| "C1QBP", | |
| "ICAM3", | |
| "CREBBP", | |
| "TLR9", | |
| "AKT2", | |
| "CSF2", | |
| "IL1RAP", | |
| "PELI2", | |
| "CXCR5", | |
| "ALOX5", | |
| "PAK1", | |
| "HMOX1", | |
| "IFNLR1", | |
| "NOX1", | |
| "NFATC4", | |
| "SSR1", | |
| "IL2RB", | |
| "RNF114", | |
| "VEGFA", | |
| "SLC2A3", | |
| "IFNGR2", | |
| "GBP2", | |
| "TPP1", | |
| "DERL1", | |
| "CD79A", | |
| "IL1RL2", | |
| "CCL11", | |
| "IL1R1", | |
| "IL1F10", | |
| "NCR1", | |
| "CD81", | |
| "PIK3CG", | |
| "MAFB", | |
| "TAB2", | |
| "VAMP3", | |
| "ATM", | |
| "CSF2RB", | |
| "GATA3", | |
| "RIPK3", | |
| "RBCK1", | |
| "TAP2", | |
| "STAT5B", | |
| "LEF1", | |
| "C3AR1", | |
| "RNASEL", | |
| "LAMP1", | |
| "EBI3", | |
| "CXCL14", | |
| "IRAK3", | |
| "DYSF", | |
| "GBP5", | |
| "HAVCR2", | |
| "TRIM56", | |
| "PRDM1", | |
| "TBXAS1", | |
| "PSTPIP1", | |
| "MAVS", | |
| "BCL2", | |
| "CD3E", | |
| "TNFSF10", | |
| "LAMP2", | |
| "DTX3L", | |
| "RHOG", | |
| "MX1", | |
| "IL4", | |
| "IFNA5", | |
| "TGFB2", | |
| "RAB5C", | |
| "THBS1", | |
| "TANK", | |
| "ACSL3", | |
| "YWHAQ", | |
| "MRC1", | |
| "LAG3", | |
| "LAT2", | |
| "SYK", | |
| "CCR8", | |
| "GUCY1A1", | |
| "TCN2", | |
| "IL2RG", | |
| "TGFBR2", | |
| "NFATC2", | |
| "TIFA", | |
| "PFKFB3", | |
| "IFITM2", | |
| "CEACAM3", | |
| "DDIT3", | |
| "CEBPB", | |
| "IL17B", | |
| "RB1CC1", | |
| "CD274", | |
| "HLA-DRA", | |
| "HSD11B1", | |
| "PARP1", | |
| "TLR8", | |
| "IL3", | |
| "CD2", | |
| "IL1R2", | |
| "HLA-C", | |
| "TIMP2", | |
| "IKBKE", | |
| "PTPN4", | |
| "C5AR1", | |
| "LIMK2", | |
| "TXK", | |
| "SELL", | |
| "TLR1", | |
| "NLRP1", | |
| "IFNAR1", | |
| "NFAT5", | |
| "IL11RA", | |
| "SPI1", | |
| "AIM2", | |
| "CCR10", | |
| "CXCL5", | |
| "TLR7", | |
| "BLK", | |
| "IL1RAPL2", | |
| "IL18", | |
| "EVL", | |
| "PSMB8", | |
| "CSF1R", | |
| "SMAD5", | |
| "IFIT3", | |
| "NEO1", | |
| "IL12RB2", | |
| "ADORA2A", | |
| "SMAD3", | |
| "SIGIRR", | |
| "CD209", | |
| "CTSG", | |
| "ALOX12", | |
| "SERPINA1", | |
| "CD28", | |
| "STAT2", | |
| "SOD2", | |
| "FBXO6", | |
| "TRAF6", | |
| "ATP6V1B2", | |
| "NCF2", | |
| "PTPN6", | |
| "SCARB2", | |
| "NFKB2", | |
| "CX3CL1", | |
| "PELI1", | |
| "RAC2", | |
| "LILRB2", | |
| "SAMHD1", | |
| "NOS2", | |
| "CCR9", | |
| "NLRC4", | |
| "CCL20", | |
| "CCL14", | |
| "RSAD2", | |
| "IL3RA", | |
| "ADGRG3", | |
| "TRAT1", | |
| "IL15RA", | |
| "SEM1", | |
| "FASLG", | |
| "RGMA", | |
| "CD163", | |
| "ATG12", | |
| "LAMP3", | |
| "CSF3", | |
| "GBP1", | |
| "CASP1", | |
| "FOXP3", | |
| "C2", | |
| "PSMB9", | |
| "HLA-DQA1", | |
| "IFIT1", | |
| "IL1RL1", | |
| "TNFRSF17", | |
| "THOP1", | |
| "KPNB1", | |
| "HSP90AB1", | |
| "DNAJA2", | |
| "NKG7", | |
| "ITGAX", | |
| "FGR", | |
| "IL24", | |
| "IL22", | |
| "MARCKS", | |
| "NAMPT", | |
| "IL1A", | |
| "NFATC3", | |
| "IFNW1", | |
| "CCL17", | |
| "KLRB1", | |
| "SORT1", | |
| "RIPK2", | |
| "GZMB", | |
| "TRIM25", | |
| "MS4A4A", | |
| "LANCL1", | |
| "IL26", | |
| "CXCR2", | |
| "MAP2K7", | |
| "IL2", | |
| "STAT1", | |
| "SH2D1A", | |
| "CCR1", | |
| "C3", | |
| "ACSL4", | |
| "CD247", | |
| "RPS6KA1", | |
| "NEU1", | |
| "EPHX2", | |
| "PIK3CD", | |
| "RBPJ", | |
| "STAT4", | |
| "LRRK2", | |
| "IL17RE", | |
| "IFI27", | |
| "MAPK1", | |
| "LTC4S", | |
| "RELB", | |
| "BECN1", | |
| "JAK2", | |
| "TAB1", | |
| "ACE", | |
| "CD8B", | |
| "MAP3K1", | |
| "XAF1", | |
| "CCL1", | |
| "MAP2K3", | |
| "PLG", | |
| "STRAP", | |
| "CD70", | |
| "ADAR", | |
| "ICOS", | |
| "TLR5", | |
| "CD69", | |
| "SP100", | |
| "CBLB", | |
| "P2RX7", | |
| "TRIM21", | |
| "MTOR", | |
| "CYSTM1", | |
| "MCL1", | |
| "MIF", | |
| "LGALS3", | |
| "IL25", | |
| "BCL3", | |
| "IFNL1", | |
| "ATF2", | |
| "GZMA", | |
| "F5", | |
| "GNS", | |
| "PTGS2", | |
| "MARCO", | |
| "ICOSLG", | |
| "PTPRC", | |
| "PIK3R4", | |
| "LITAF", | |
| "MAPK14", | |
| "RAF1", | |
| "ITLN1", | |
| "MYC", | |
| "GCA", | |
| "NCF4", | |
| "OSM", | |
| "IFIT2", | |
| "IL17RC", | |
| "LAT", | |
| "IFNB1", | |
| "ALPL", | |
| "NGLY1", | |
| "UBA52", | |
| "CD19", | |
| "IFI6", | |
| "ENTPD1", | |
| "APP", | |
| "CD59", | |
| "TRIM6", | |
| "TBX21", | |
| "CASP3", | |
| "TRAF3", | |
| "CCL7", | |
| "CALM1", | |
| "ATG10", | |
| "HLA-DRB4", | |
| "ACKR2", | |
| "HK3", | |
| "ATG13", | |
| "DHX58", | |
| "IL11", | |
| "SIGLEC5", | |
| "CCL21", | |
| "TGFB1" | |
| ], | |
| "Coefficient": [ | |
| -0.13612941844202447, | |
| 0.11274592529056482, | |
| -0.10157247406465322, | |
| -0.09797308685220364, | |
| 0.09723255999904497, | |
| 0.0960662464350341, | |
| 0.08915918201348458, | |
| 0.0874260439950769, | |
| 0.08548297629790927, | |
| 0.08512118070499737, | |
| -0.08367608722521944, | |
| -0.08366235541975041, | |
| -0.08326127825900996, | |
| -0.08208249431300457, | |
| 0.07922214484998208, | |
| 0.07795041317922145, | |
| 0.07616638859917388, | |
| 0.0753445306009298, | |
| -0.07513853009575587, | |
| 0.07439415234105319, | |
| 0.07368967655778429, | |
| -0.07356149553560506, | |
| 0.07108803103692612, | |
| -0.07089043307327836, | |
| -0.0708778537392462, | |
| -0.07084132562030009, | |
| 0.0708090929039722, | |
| 0.07049389171849359, | |
| -0.07007562777089203, | |
| -0.06986801759521741, | |
| 0.06964380082457368, | |
| -0.06932721024610748, | |
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| -2.500966922321911e-05 | |
| ], | |
| "Absolute Coefficient": [ | |
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| }, | |
| "cv_performance": { | |
| "prediction": { | |
| "accuracy": 70.0, | |
| "precision": 73.4816344228109, | |
| "recall": 74.46020023818885, | |
| "f1": 73.93023546423112 | |
| }, | |
| "selection": { | |
| "precision": 10.554089709762533, | |
| "recall": 100.0, | |
| "f1": 19.093078758949883, | |
| "jaccard": 10.554089709762533 | |
| } | |
| } | |
| } |