{
    "significant_genes": {
        "Variable": [
            "CTSG",
            "BFAR",
            "DSC1",
            "IGFALS",
            "HSFY2",
            "TMEM106A",
            "VNN3P",
            "CDHR2",
            "FNDC7",
            "CD200R1L",
            "HOTAIR",
            "MCM10",
            "CD300LD-AS1",
            "NEUROD2",
            "CYTL1",
            "ZNF295-AS1",
            "ADPRM",
            "PI4KAP1",
            "LGALS7B",
            "LILRB5",
            "ANO7",
            "NLRP10",
            "FAM3B",
            "IL23R",
            "PDHA2",
            "TUBBP5",
            "TFDP3",
            "MS4A10",
            "SNORA11B",
            "EMC2",
            "STH",
            "GDNF",
            "RSL1D1",
            "SLCO4C1",
            "KC6",
            "DDX20",
            "IFNLR1",
            "CYP4Z2P",
            "TBX20",
            "GPA33",
            "OR2W1",
            "WASHC2A",
            "PKDCC",
            "NCAN",
            "RHBDL3",
            "OR1D4",
            "TRIM4",
            "MCCD1",
            "LOC344967",
            "ORC4",
            "ACOXL",
            "OR2T2",
            "BTBD16",
            "GALNT8",
            "ONECUT1",
            "SCGB1C1",
            "OR52H1",
            "HCG9",
            "C1QTNF9B",
            "OR2A5",
            "OTOA",
            "GRXCR2",
            "OR4P4",
            "SPATA31E1",
            "SLC32A1",
            "TAS2R5",
            "C4BPA",
            "KRTAP10-10",
            "LINC00469",
            "PRKAG3",
            "NAT8B",
            "OR7E37P",
            "C10orf95",
            "SCX",
            "FLJ13224",
            "KCNH4",
            "GAB4",
            "EME1",
            "CHRAC1",
            "OTC",
            "TULP3",
            "LOC100240734",
            "LIPK",
            "SHOC1",
            "TMEM30CP",
            "SERPINB13",
            "SNORA56",
            "GPR37L1",
            "FBLL1",
            "OR2M4",
            "SNORA11E",
            "MAGEC2",
            "OR10A3",
            "TRIML1",
            "PHGDH",
            "CAGE1",
            "S100Z",
            "TRPM5",
            "OR10R2",
            "POU5F2",
            "GPR52",
            "DRD5",
            "ZBTB22",
            "ATP1B4",
            "NCKIPSD",
            "SERPINB4",
            "FAM182A",
            "UNCX",
            "ASAH2",
            "TAS2R43",
            "SSTR5",
            "COL11A2",
            "SEC14L5",
            "SLC5A11",
            "SLC22A8",
            "C1D",
            "GOLGA7",
            "FRMPD2B",
            "SPINT3",
            "OR6F1",
            "UCP2",
            "IL19",
            "CFAP36",
            "ANKS4B",
            "RLN3",
            "C5orf52",
            "OLIG3",
            "KRTAP12-4",
            "LEUTX",
            "LOC100129935",
            "CLTRN",
            "LOC154449",
            "COL19A1",
            "OR56A1",
            "CYP26C1",
            "SNORA58",
            "RSPH10B2",
            "COX8C",
            "ALDH1A1",
            "NXPH2",
            "LOC100130691",
            "DISP1",
            "AMER3",
            "RIPPLY2",
            "DNAAF6",
            "KRTAP10-8",
            "GPR137B",
            "OXER1",
            "POU3F3",
            "FAM66D",
            "LOC642846",
            "PROKR2",
            "SLC47A2",
            "PSG2",
            "CYP27B1",
            "OR1J4",
            "GPR151",
            "ALG1L2",
            "OR4M2",
            "LCE5A",
            "ACSBG1",
            "MAL",
            "KLF11",
            "VCPKMT",
            "GUCY2C",
            "MAT1A",
            "KRTAP13-2",
            "PROP1",
            "TUBAL3",
            "SNORA37",
            "AADACL3",
            "CEACAM8",
            "DEFB109B",
            "CRYGD",
            "FAM9A",
            "SPIN2A",
            "PCDHGA6",
            "WBP2NL",
            "TTC32",
            "RBMY1B",
            "WNT16",
            "UGT2B10",
            "BTNL3",
            "OR52B6",
            "SERPINA13P",
            "OR2L8",
            "H2AC12",
            "GPR89B",
            "C9orf152",
            "PGA4",
            "OR51I2",
            "SERPINC1",
            "XKR9",
            "GKN1",
            "GMPR",
            "ZFAT-AS1",
            "HOXC5",
            "FAM47A",
            "C16orf90",
            "HSP90AB2P",
            "KRTAP9-8",
            "SMTNL1",
            "SPIN4",
            "SLC17A8",
            "SPATA1",
            "TP53TG5",
            "CNGA3",
            "CRISP3",
            "CYP11B2",
            "KCNH1",
            "IGBP1P1",
            "CFAP100",
            "EPS8L3",
            "NUTM2G",
            "FBXO40",
            "FSCN3",
            "LINC00114",
            "ACTRT1",
            "VWC2L",
            "MRPL3",
            "ZDHHC18",
            "WDR41",
            "HTR3D",
            "OR1L4",
            "LINC00479",
            "DEFB135",
            "HSD3B1",
            "TEX55",
            "MMP8",
            "OR51A7",
            "NUTM1",
            "DSCR10",
            "LCN8",
            "SLC25A41",
            "SLC7A11",
            "LINC00313",
            "ADAMTS19",
            "SCARNA23",
            "OR10G8",
            "H1-4",
            "OR2T10",
            "GAGE2C",
            "CLEC4GP1",
            "PAX4",
            "GOLGA6A",
            "SPINK7",
            "PTBP1",
            "SLC6A1",
            "SPATA3",
            "CCL1",
            "CDKL4",
            "PPY2P",
            "OR14J1",
            "LRRC8E",
            "ZNF681",
            "SYT10",
            "ZBTB14",
            "SNX32",
            "OR5AK2",
            "PYY2",
            "FAM153B",
            "TTLL8",
            "TBL1Y",
            "EXO5",
            "ZNF716",
            "SIAH1",
            "IL1RAPL1",
            "ARL17B",
            "ASB4",
            "POU4F2",
            "NPVF",
            "ZKSCAN8P1",
            "BHLHE23",
            "ZNG1F",
            "GABRA1",
            "AADACL4",
            "SRMS",
            "IFNL1",
            "KRTAP4-11",
            "GPR20",
            "NPC1L1",
            "TAS2R7",
            "OMP",
            "KATNBL1",
            "KCNQ5",
            "RHOXF2B",
            "VN1R5",
            "PCDHGA5",
            "XAGE3",
            "BTG2",
            "OR8D2",
            "TDRD3",
            "OR10G2",
            "FABP12",
            "UGT3A2",
            "TRIM55",
            "NBPF22P",
            "LCN9",
            "PLA2G1B",
            "PCDHB11",
            "PRG1",
            "ANKRD30A",
            "IL6",
            "FMR1NB",
            "OR6K3",
            "OR7E156P",
            "LENEP",
            "SLCO1B3",
            "OR4C3",
            "F7",
            "KRT84",
            "GNRHR",
            "FKBP1AP1",
            "NEK3",
            "GSTT2",
            "VAX2",
            "OR4N4",
            "RNF103",
            "BRME1",
            "ASB12",
            "AGMO",
            "CHRNA10",
            "SNORA67",
            "GOLGA8F",
            "SIX6",
            "MARCHF5",
            "RAB22A",
            "METTL15",
            "SPATA31A3",
            "PNPLA1",
            "PEDS1-UBE2V1",
            "ZAN",
            "OR5H6",
            "ANGPTL3",
            "C2CD2L",
            "LCE3E",
            "OR8I2",
            "LINC00207",
            "CAPZA3",
            "C3P1",
            "LINC00244",
            "OR10H4",
            "PANX3",
            "SLC46A3",
            "NXF2",
            "ADAD1",
            "PCDHB16",
            "DEFB127",
            "ATP4B",
            "TCAM1P",
            "IL22",
            "CLDN18",
            "RNASE4",
            "OR5M1",
            "OR6X1",
            "IL27",
            "REG4",
            "OR9A4",
            "H3C8",
            "SPINK8",
            "LINC02860",
            "CDY2B",
            "POGLUT3",
            "UTF1",
            "PCDHGC3",
            "RAX2",
            "ODAPH",
            "GBP7",
            "TMEM31",
            "CIMIP1",
            "TM4SF5",
            "KCNJ9",
            "GPR179",
            "FAM217A",
            "IGSF5",
            "MSX2P1",
            "TBC1D3",
            "EIF3C",
            "NKX2-6",
            "OR13C3",
            "FSHB",
            "HLA-J",
            "H4C12",
            "CYP1A1",
            "RFPL1",
            "LOC100133920",
            "IFNK",
            "OR5V1",
            "PNMA8A",
            "ESRRB",
            "UGT2A1",
            "C1QL4",
            "RXFP4",
            "NCBP2",
            "IL5",
            "TUBA3C",
            "CSMD1",
            "CAMKV",
            "TRIM43",
            "SOX15",
            "NEUROG2",
            "TDRD5",
            "BPIFB3",
            "CLPSL2",
            "DLEU2L",
            "PLA2G2C",
            "DKKL1",
            "NUDT12",
            "THNSL2",
            "HBM",
            "UGT1A3",
            "CXorf51A",
            "FAM215A",
            "RHOXF1",
            "SNORA5B",
            "GSTA5",
            "PKD1L3",
            "OR10K1",
            "CMYA5",
            "ACCSL",
            "TLX1NB",
            "POU2F1",
            "TGM6",
            "OR1A2",
            "FAM74A4",
            "ASPDH",
            "TAAR6",
            "CEACAM22P",
            "TLX1",
            "NEUROG1",
            "TAF7L",
            "MED4",
            "LOC100271832",
            "FSCB",
            "OR10Z1",
            "SPACA7",
            "ZFP91-CNTF",
            "METTL27",
            "SAYSD1",
            "KCNJ10",
            "DHX40P1",
            "SLC22A11",
            "TPTE",
            "KLHL35",
            "SLC22A18AS",
            "INSYN2A",
            "GLIPR1L2",
            "PDCL",
            "PLEKHG3",
            "PLGLA",
            "NELL1",
            "RGPD8",
            "POMC",
            "AWAT1",
            "LRRC18",
            "ERCC5",
            "GASK1A",
            "IFNL3",
            "PTH",
            "FAM107A",
            "NPHS2",
            "ARV1",
            "OR1L3",
            "KRTAP3-2",
            "GH2",
            "IFNA17",
            "PSRC1",
            "NEU2",
            "FMO3",
            "CCL24",
            "TTTY6",
            "RNF113B",
            "LINC00523",
            "PRSS48",
            "LYPD2",
            "OR7A10",
            "GHSR",
            "POU1F1",
            "PENK",
            "HYAL4",
            "TENT5D",
            "DEFA5",
            "DRAM2",
            "DLK1",
            "KATNIP",
            "OR2V2",
            "LIPM",
            "ADAM21P1",
            "LTK",
            "KRT33A",
            "SERPINB3",
            "TAFA4",
            "BPIFB6",
            "MUC7",
            "LINC00189",
            "LYNX1",
            "POU2AF2",
            "TEX44",
            "KRTAP5-4",
            "ABCD1",
            "OR6N1",
            "OR11L1",
            "RNASE13",
            "SLC24A2",
            "C12orf71",
            "SNORA5C",
            "OR7G1",
            "LOC728989",
            "FAM99A",
            "TMPRSS15",
            "GOT1L1",
            "RNASE8",
            "CSN1S2AP",
            "MS4A13",
            "FOXG1",
            "GSTT4",
            "CACNA1S",
            "TAS2R1",
            "PTGDR2",
            "RNF26",
            "POU4F3",
            "ACTC1",
            "TMIE",
            "MMP26",
            "PPP1R10",
            "HOXB1",
            "APOBEC1",
            "PHKG1",
            "DPRXP4",
            "ZFP36",
            "ADAM11",
            "KRTAP19-2",
            "PRMT6",
            "PSG11",
            "CA12",
            "CPA6",
            "SDHAP2",
            "ANKRD20A4P",
            "LGALS4",
            "GAGE12F",
            "PCDHB12",
            "CXorf66",
            "DEFB107A",
            "KIF4B",
            "EVX1",
            "PXDNL",
            "GLYCAM1",
            "OR5K1",
            "KIAA1549L",
            "LCE3B",
            "KRTAP4-5",
            "SERPINI2",
            "GAGE2E",
            "TBC1D21",
            "NAIP",
            "FAM9C",
            "KIR3DL1",
            "PPIAL4A",
            "FAM24A",
            "OPN1SW",
            "KRTAP5-5",
            "SEPTIN14",
            "KRTAP22-1",
            "FAM99B",
            "KRTAP25-1",
            "KRTAP20-2",
            "CFAP92",
            "BPY2",
            "CT47A10",
            "CT45A6",
            "CT47A1"
        ],
        "Coefficient": [
            -3.5850095674266758,
            2.754448555212461,
            -2.6237953948685746,
            -2.598394081641721,
            2.5762870154664252,
            2.5567188784601336,
            2.5014210580752154,
            -2.3923194145540716,
            2.0859470366517203,
            2.0609222191389636,
            1.9685837805076527,
            -1.9653032842943225,
            1.9481883763775432,
            1.837880985630073,
            -1.8319410153012252,
            -1.7977123491918479,
            1.7826674406702798,
            1.7799085145062399,
            1.7681300203493528,
            -1.748955593123343,
            1.7013877140653273,
            -1.699183029867758,
            1.6968809485781533,
            1.6849155432009886,
            1.6806566001864671,
            1.679874658094351,
            -1.6290583183682532,
            1.6244020418765128,
            1.6229246758912237,
            1.6225618001083555,
            1.6119300709470712,
            -1.5982195525516856,
            1.5967009449404734,
            1.567037009811609,
            -1.5501378804707442,
            -1.5401602438514062,
            1.5315921386248648,
            -1.5100257076744559,
            1.5042045731391318,
            -1.4803988740533882,
            -1.4484154108421612,
            1.4443467930237421,
            1.4263786883513165,
            1.4181365060633917,
            1.4115590006408756,
            1.4007136688104744,
            1.4006358539385508,
            -1.3844501627357053,
            -1.3819479926079081,
            -1.3723438932756735,
            1.3614455991186578,
            -1.3581613348202541,
            -1.3454852583217054,
            -1.3361268340417283,
            -1.335626783479871,
            1.2898074987236,
            1.282884668039719,
            1.260660843441799,
            -1.2569603633475184,
            -1.2543628031828624,
            1.2539223308826897,
            1.240011007222001,
            -1.2363957545657427,
            -1.2325847960760683,
            -1.2298931969669684,
            -1.2271832082735266,
            1.2270771717245847,
            1.225789147552945,
            -1.217098547941967,
            1.2134937873315215,
            -1.2068170663951656,
            -1.2055551348464841,
            1.1934529391705364,
            -1.1715411195376877,
            1.1670329356397018,
            -1.160257941265539,
            -1.1555585923135898,
            -1.1442885016154067,
            -1.1441155677247221,
            1.1433997552757595,
            1.124626989699981,
            1.1202080764942133,
            -1.1185743779772528,
            1.107901122652601,
            1.103738066777882,
            -1.0905466965085824,
            -1.0829198166403058,
            -1.0824774510822046,
            -1.0770128842810878,
            -1.0654597243131094,
            1.064806667446918,
            1.0629153899137782,
            -1.059719721360954,
            -1.0576534611091055,
            -1.0518728157478876,
            -1.0491866879418241,
            -1.0469075559317218,
            -1.0312207741945383,
            1.0268975056463339,
            1.0250436682403052,
            -1.0140147507398625,
            -1.0137616057306347,
            -1.0068371758735735,
            1.006239731583435,
            1.0014324984834329,
            -0.9811275645946472,
            -0.9806953590136335,
            0.9761655797494614,
            0.9756990441435375,
            -0.9745304464697464,
            -0.9716362353235067,
            -0.9701853298571552,
            -0.966137959465183,
            0.9640660271547549,
            -0.9551835789056982,
            -0.9444663129392357,
            -0.9272661122053816,
            0.9249514305910562,
            0.9208511283733155,
            0.9176095865222011,
            0.91639713085351,
            0.9098878298282314,
            0.8960879021794215,
            0.8934323811202998,
            0.8873230261119096,
            -0.8868032551133577,
            -0.8840202266364774,
            0.8800024388532428,
            -0.8764631021808684,
            -0.8705400204516273,
            0.861149557451877,
            0.849043438549,
            0.8480201200079116,
            -0.8416898505207983,
            -0.839428414641682,
            0.8375047183668696,
            0.8374964632019364,
            -0.8243187747442692,
            -0.8180417322769022,
            -0.8093294726982789,
            -0.8092163457126688,
            -0.8039074015470178,
            0.8030291153856651,
            -0.8013275309536828,
            -0.7952737591628523,
            -0.7874413169375083,
            0.7799003852380464,
            0.7778168272509404,
            -0.7664826298864784,
            0.7643996765758105,
            0.7598109951619167,
            -0.7588154222749866,
            0.7565795090225973,
            0.7558644241104933,
            0.7529199931208335,
            -0.7521361155147647,
            0.7516444652264794,
            0.74929101035819,
            0.744765489956002,
            0.7417975895030028,
            0.740949428641534,
            0.7401909242057492,
            0.7390656646805958,
            -0.7353110939780881,
            0.7346098315059467,
            -0.7335842338837341,
            0.7325275088083919,
            0.73100182880182,
            0.7269376800600191,
            -0.7253442029426395,
            0.7249513608691193,
            -0.7248068747211341,
            0.7219538669614541,
            0.718028322313615,
            0.7159118507078651,
            0.7139302840678733,
            -0.7131053052249297,
            -0.7128922090516115,
            -0.7100132860872409,
            -0.7084043431057667,
            0.7054487091821509,
            0.7027851319594791,
            0.6975537565910913,
            -0.6848789534262384,
            0.6829376232873188,
            -0.6816951884445397,
            0.6772717610571762,
            0.6759570232700965,
            -0.6741094618382251,
            -0.6732307555708043,
            0.6729054752575279,
            0.656089755391028,
            -0.655362265506464,
            -0.6490372948528312,
            0.6471345191450177,
            0.6464329059921597,
            -0.6457558773317494,
            0.6432487455582472,
            -0.641156328061828,
            0.6392682667555125,
            0.6363452871117768,
            0.6318455322694873,
            -0.625861138386873,
            -0.6226218252939474,
            -0.6127216649761422,
            0.6088922188735988,
            -0.6004652956487578,
            0.5962706049747629,
            -0.5904481449039812,
            0.5901606034272637,
            0.5895546439434257,
            0.5798650535787989,
            0.5741924526948763,
            0.5704904434719372,
            0.5697840438904354,
            0.5685691501863857,
            0.5655969273563307,
            -0.5651541551238825,
            -0.563714098876957,
            0.5611652599450246,
            0.56100407510915,
            0.5608475394529837,
            0.5551225402780021,
            0.5542412031505372,
            -0.552093050198559,
            -0.5509292194692078,
            0.548580366180149,
            0.5480009068492868,
            0.5454539717883962,
            -0.5417209046192502,
            -0.5340550548504842,
            -0.5339253267399972,
            0.5291546282796804,
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