{
    "significant_genes": {
        "Variable": [
            "ABCC9",
            "ABCA8",
            "ABHD11",
            "IFNA17",
            "ABCA7",
            "ABCC8",
            "DRGX",
            "ABRACL",
            "COL26A1",
            "CRISP2",
            "BCL2L11",
            "ABCC1",
            "KIR3DL3",
            "ADAMDEC1",
            "GJA5",
            "AASS",
            "ADAM29",
            "AMZ1",
            "OR2L8",
            "ETV1",
            "ABCA10",
            "ST8SIA3",
            "ADISSP",
            "CDC42EP4",
            "PEG3-AS1",
            "ARL5C",
            "LRTM1",
            "METTL21C",
            "ABCD2",
            "LINC00293",
            "CFH",
            "ADRB3",
            "FN3KRP",
            "ACACA",
            "ABCA12",
            "CFC1B",
            "CD28",
            "VN1R1",
            "ABCA9",
            "ACYP1",
            "CSMD3",
            "CFHR3",
            "CAMK1G",
            "FBP2",
            "C1orf141",
            "KIR2DL3",
            "AFG3L2",
            "ARID5A",
            "NPAP1",
            "CLEC4M",
            "CRYBA1",
            "VWC2L",
            "ABRA",
            "AP2A1",
            "JAG2",
            "ECHDC3",
            "RGSL1",
            "TAAR1",
            "CEACAM20",
            "OR7G2",
            "ADM2",
            "DCP2",
            "AP1B1",
            "MMP23A",
            "ARHGEF26",
            "OR4F6",
            "MUC16",
            "DLEU2",
            "ACTMAP",
            "CD300LD",
            "ANLN",
            "SV2C",
            "NALCN",
            "CCDC71",
            "PRDM13",
            "ABCB1",
            "DPEP1",
            "C20orf141",
            "SLC12A3",
            "C1orf94",
            "COLEC10",
            "ZNF385B",
            "BORA",
            "ABHD3",
            "DUOXA1",
            "CSN2",
            "SNHG11",
            "CYP19A1",
            "ABCA6",
            "SLC6A10P",
            "LUZP4",
            "ACTR3B",
            "CHRND",
            "HCLS1",
            "IER2",
            "PLA2G2A",
            "LINC00028",
            "SLC22A10",
            "SNORA20",
            "OR11L1",
            "ATP6V0E2",
            "FLJ42393",
            "AIMP1",
            "AHCY",
            "CST2",
            "C17orf58",
            "DUOXA2",
            "ABL1",
            "GAB4",
            "GNGT1",
            "PIP5KL1",
            "ATP6V0A4",
            "TSC22D3",
            "FAM138F",
            "DGAT2",
            "ABRAXAS1",
            "OR4E2",
            "ACTA2",
            "CADPS",
            "ABCB6",
            "ADRA1D",
            "ABCC4",
            "CES4A",
            "SRGAP2",
            "SULF1",
            "SPINT3",
            "EMC4",
            "DENR",
            "SEC1P",
            "PRNT",
            "KRTAP4-5",
            "GPX5",
            "OR52K2",
            "CACNA1S",
            "ONECUT2",
            "SUPT3H",
            "DYNLT5",
            "CEACAM5",
            "CELA2A",
            "CALCR",
            "STYX",
            "GPR87",
            "LCE6A",
            "CDC25C",
            "OR2M1P",
            "MATN3",
            "C22orf42",
            "CNGB3",
            "ECEL1",
            "TDRD10",
            "MCEMP1",
            "DHH",
            "DEFA6",
            "SPOCK2",
            "AACSP1",
            "FEM1A",
            "COL10A1",
            "ABI3BP",
            "DMRTC1",
            "FOXF2",
            "ZNF788P",
            "NPY1R",
            "AKNAD1",
            "HUS1B",
            "SNORA32",
            "REXO6P",
            "GCNT7",
            "ASS1",
            "TCF21",
            "MGC27382",
            "NMUR2",
            "ALAS2",
            "ALG6",
            "ZNF714",
            "GKN1",
            "TAAR5",
            "MAGEB16",
            "TSPAN19",
            "NPFFR2",
            "ARHGEF39",
            "SPATA24",
            "STRADB",
            "H2BC8",
            "GNAI1",
            "AGRP",
            "PNPLA2",
            "TMPRSS11B",
            "LSMEM2",
            "ADIPOQ",
            "FOXA1",
            "SUN5",
            "NHLH2",
            "ALDH4A1",
            "LOC344967",
            "ESR2",
            "DAPK3",
            "IL15RA",
            "DNAH8",
            "DLX4",
            "DDX25",
            "ACLY",
            "H4C12",
            "ARL14EP",
            "OTX1",
            "CCDC54",
            "TMEM145",
            "APOO",
            "KCTD15",
            "SYCP3",
            "TEX44",
            "ADAMTS5",
            "SLC6A4",
            "SLC14A1",
            "ASB18",
            "CEACAM4",
            "UTP3",
            "VAX2",
            "ACOT4",
            "GPR158",
            "OR1K1",
            "CFHR5",
            "FSTL5",
            "OR1L4",
            "GRIK3",
            "H2BC18",
            "GDPD4",
            "PNMA1",
            "AQP8",
            "DMRTB1",
            "ADCY2",
            "RIPPLY3",
            "PGA3",
            "TNMD",
            "FAM117B",
            "DKK2",
            "C1orf53",
            "OR8G5",
            "OR51D1",
            "LALBA",
            "ASF1B",
            "CLEC18A",
            "CA11",
            "HAO1",
            "LHX9",
            "FGF10",
            "DOK6",
            "SNORA70B",
            "OR3A2",
            "KCTD4",
            "INE2",
            "HSD3B2",
            "AGBL5",
            "TOX",
            "LRRN3",
            "CFHR1",
            "CLCN1",
            "ATP5MF",
            "SPATA12",
            "ZNF793",
            "ACTL7B",
            "SPATA31G1",
            "EIF3M",
            "GYPE",
            "TMEM89",
            "ZNF93",
            "KLRC2",
            "CENPF",
            "GARIN4",
            "HCG22",
            "UBE2DNL",
            "ATP11AUN",
            "OR10X1",
            "GPRC5D",
            "AUNIP",
            "APOBEC3G",
            "ASPA",
            "ACSL5",
            "CFHR2",
            "ARHGEF37",
            "TMEM74",
            "OR10J3",
            "NEGR1",
            "OR51T1",
            "TRIM71",
            "CEP19",
            "IFNA10",
            "AZIN1",
            "TARM1",
            "GPR62",
            "MSH4",
            "ACOX1",
            "MYH6",
            "SNORA31",
            "ADCY8",
            "SULT1B1",
            "HBB",
            "TAS2R50",
            "SLCO1C1",
            "FGF14",
            "OR14A16",
            "OR10G3",
            "PRSS37",
            "ACTN1",
            "CAB39L",
            "RESP18",
            "CELA3B",
            "OR13C9",
            "CUX1",
            "ZNF875",
            "ZBTB3",
            "CYP2R1",
            "KRTAP5-7",
            "ABI2",
            "HLCS",
            "LINC02878",
            "CLIC6",
            "ITPK1-AS1",
            "ACTL9",
            "CADPS2",
            "KLHL10",
            "CPN2",
            "DKFZp434L192",
            "KCNK17",
            "OR13J1",
            "ABCF3",
            "RXFP2",
            "RTL4",
            "VSIG1",
            "GALNTL6",
            "CYP2A6",
            "PRR35",
            "SNORA65",
            "ACER1",
            "POU2F2",
            "UPP2",
            "ARHGEF10",
            "LTK",
            "CARD9",
            "CEACAM7",
            "SAA3P",
            "IZUMO1",
            "ASB1",
            "NOTCH3",
            "TAS2R40",
            "TNP2",
            "KRTAP12-2",
            "FERD3L",
            "NKX3-2",
            "KRTAP5-3",
            "ADGRL3",
            "BCL2",
            "FUT1",
            "CTNNA3",
            "ELOA2",
            "ARID3A",
            "SLC38A6",
            "H2BC5",
            "ACTN3",
            "SAMD13",
            "TPTE2",
            "CDH26",
            "FAM221B",
            "PHF21B",
            "CEP250",
            "AURKA",
            "FCN3",
            "FRMD8",
            "RWDD2B",
            "BTN3A3",
            "FIBCD1",
            "TECTB",
            "OPCML",
            "BDNF-AS",
            "POLR1E",
            "TCFL5",
            "OR1I1"
        ],
        "Coefficient": [
            -0.04222453490126355,
            -0.02456614204184579,
            0.023623098439624055,
            0.022857508438450476,
            0.022485658483138767,
            -0.02141284709405084,
            -0.020429427960981975,
            0.017961946606632882,
            0.017366017725182897,
            -0.016638504389767696,
            0.016551070643133957,
            0.015343262084937017,
            -0.014186192514226476,
            0.014109265160843522,
            0.013949648113645984,
            -0.013621758480139341,
            -0.013429580066787277,
            -0.013246504622016814,
            -0.013185108582648347,
            0.013044161755570115,
            -0.012664241202434206,
            0.012412162831455529,
            -0.01234670366945493,
            -0.011660018103697338,
            0.011136449585595948,
            -0.010868894489857627,
            0.01084390988823786,
            -0.009688857279826147,
            -0.009505663617922402,
            0.009188289595775745,
            0.009166827751531064,
            -0.009165772370350394,
            -0.009086054317470442,
            0.009067030412056113,
            0.008780157046260686,
            -0.008451933593608872,
            0.008445416601877495,
            0.008362798165863243,
            -0.008216286321499667,
            0.008112260364218476,
            0.008049004876954471,
            0.008043418971364121,
            0.007989740513318386,
            0.00789763821360489,
            -0.007865196444744645,
            -0.007689081686264527,
            0.0072162209153160866,
            -0.007137986679945364,
            -0.006720754997297246,
            -0.0065796121280668005,
            0.006551458022472,
            0.006410562091524865,
            -0.0061198352547537326,
            -0.006008920572255348,
            0.0058615987973799225,
            -0.005754857952865179,
            0.0057009095908865295,
            -0.005659875778063404,
            0.005487590165671391,
            0.005433570149884711,
            0.005350272980859583,
            0.005312189807239552,
            0.005222895689979584,
            0.00513542138007587,
            -0.0049193468613273296,
            -0.004889346895180789,
            -0.004878746170951612,
            0.004868315109028514,
            0.0047348011394893275,
            0.004386279464245087,
            0.004363891986749577,
            0.0043237719825228406,
            0.004313393699996036,
            -0.004272877699772157,
            0.004268827418435638,
            -0.0042291316476985455,
            0.004180075558788608,
            -0.00417734618861405,
            0.004100697841248717,
            0.003982483678774508,
            0.003964263333998172,
            0.0038977624250675818,
            0.0038039155315399338,
            0.0037990089512095894,
            -0.0037819936142956035,
            0.003642755533327212,
            0.0036422518706489514,
            0.0036180892733832823,
            -0.0035682590490680247,
            0.003426572130321806,
            -0.003405945547106462,
            0.003329950676562004,
            0.0032894430070745484,
            0.0032754523866976664,
            -0.0032452726000843915,
            -0.0032387864679198236,
            -0.003230178221730777,
            -0.003220193000594081,
            -0.0032083473905470893,
            0.003177443985601981,
            0.003155188548987009,
            -0.0031366908145118717,
            -0.003090825909052314,
            0.003080001272574949,
            0.0030301029595065764,
            -0.0030195596642495215,
            -0.002994429425066821,
            -0.002990584864493757,
            0.0029580562707442666,
            0.0029201090778582187,
            -0.002878461564633466,
            0.002857651284454967,
            0.002845587005249375,
            -0.0028301300552568023,
            0.002758425534260863,
            -0.0027450577256755214,
            0.0026958319545472946,
            -0.0026807200396718987,
            0.0026146807722699558,
            0.0025682146062886825,
            -0.0025452937502384583,
            -0.002507566769122218,
            -0.002507375046621196,
            0.0025023334976310703,
            0.0024797064868333557,
            -0.00246143840682469,
            -0.0024365080328113318,
            0.0024109162510989974,
            -0.0024026128329814015,
            -0.002395291250441697,
            -0.002393421593983257,
            0.0023882007757354265,
            0.0023220410535036698,
            0.0023131660029905346,
            0.002223489316416364,
            0.002185014567043918,
            -0.002151293558833973,
            0.0021463791392183538,
            -0.002143719092307806,
            0.0020316168303285494,
            0.001997489417446391,
            0.0019636903304312697,
            -0.0019538902947782173,
            0.001936888427748105,
            0.0019251476047278844,
            0.0019190990685044674,
            0.0019128353124413695,
            -0.0018632474122329775,
            0.001801685382642146,
            0.0017819343276236303,
            0.0017726386393639854,
            0.001744730128484667,
            0.001713581975079814,
            0.0017084559720061203,
            0.0017017656251617512,
            -0.0016641031969701853,
            0.0016114080356368602,
            -0.0015871797031239848,
            -0.0015818346971552572,
            0.001570411167872475,
            0.0015660439164125034,
            0.0015080432597245987,
            -0.0014881107181776594,
            0.001486333927808089,
            -0.0014731820467708096,
            -0.001472458167801111,
            0.0014628492658555563,
            -0.0014481794265122654,
            0.0014429358614568774,
            0.0014317489175690937,
            0.001412713599363465,
            0.0014033899455297757,
            0.001394209207038196,
            0.001393209868288351,
            0.001378871642901044,
            0.0013729274912186668,
            0.0013335107073751,
            0.001327311362057099,
            0.0013257476169788091,
            0.0012851517806262472,
            0.0012665512646341927,
            0.0012434000466954205,
            0.0012113158969382738,
            0.00116506670307724,
            0.001154785832493137,
            -0.001131429838708935,
            0.001119058853571757,
            -0.00111319799861923,
            -0.0010869809614851885,
            0.0010861717888004515,
            -0.0010783267472879038,
            0.0010752312001477084,
            0.0010731982833491363,
            0.0010595595237568635,
            0.001039948446123502,
            -0.0010337041266506419,
            -0.0010012541067798831,
            0.0009873269821836278,
            0.0009711684260609147,
            0.0009700825280784734,
            0.0009403593398245921,
            0.0009088851995127409,
            -0.0009086132997199322,
            0.0008964275742193996,
            -0.0008830498746657577,
            0.0008458840559950739,
            0.0008305599057388212,
            0.000829984464625012,
            -0.0008177542742881793,
            0.0008120493451910312,
            -0.0007950536558698952,
            -0.0007878333818403391,
            0.0007868920574406591,
            0.0007620530291064112,
            0.000760884219468816,
            -0.0007474807979951526,
            0.0007438365865429012,
            0.0007328672360887474,
            0.0007293380109245519,
            -0.0007143161956414208,
            0.00071211383205459,
            0.0007072277267557184,
            -0.0007039721390219501,
            0.000700367150549657,
            0.0006744299829522781,
            0.0006724787685416468,
            0.000625293025358347,
            -0.0006219209470173852,
            -0.0006099034975888851,
            -0.0006056057067319249,
            0.0006048080339965421,
            -0.0006027691057233552,
            0.0005947586343746629,
            0.0005857396565581374,
            0.0005842424662569341,
            0.0005769094910875317,
            0.0005568343863445243,
            -0.0005380153515858761,
            0.000532047618941633,
            0.0005269711130704373,
            0.0005266791138421203,
            -0.0005163364185593707,
            0.000504752491905733,
            0.0004986494721146024,
            -0.0004890113163847297,
            0.00048058743485198226,
            0.00046362927666137,
            -0.0004514901724252544,
            0.0004433577757192038,
            -0.00043710595734724913,
            0.000435250494341576,
            0.000432327832218144,
            0.0004317011491889021,
            0.00042917636268243484,
            0.0004123957632918692,
            -0.00041234714136773965,
            0.00039996563625570075,
            -0.0003989332595434067,
            0.0003941777209646386,
            0.0003926197369045445,
            -0.0003862872533284114,
            -0.000383977748269993,
            -0.00038215034864683064,
            0.00036504405519937754,
            0.0003641290710648027,
            -0.0003637331305999674,
            0.00036000265185388353,
            -0.00035758088821906213,
            0.00035704188487386374,
            -0.0003477984231510398,
            -0.00034458070759921656,
            -0.0003380309072121372,
            0.00033531750703107404,
            0.00032776178910716804,
            -0.0003266829001202788,
            -0.00032589489139401163,
            -0.0003251643728681404,
            0.00032163406303259477,
            -0.0003055323431203415,
            0.0002950761343496091,
            0.0002940442688942386,
            0.0002838148552618996,
            0.0002811004315737263,
            0.00027817530244733413,
            0.000269203712218563,
            0.0002637982883884468,
            0.00024473368201679847,
            0.00024165230524533942,
            -0.0002189790044682277,
            0.0002179740948168498,
            0.00020949614751337753,
            0.00020825731211458946,
            0.0001996118401083192,
            -0.00019271669005396192,
            0.00019267331533965248,
            0.00018171648334915674,
            -0.00016934346839812483,
            0.00016783831963179303,
            0.00016685350465298274,
            0.00016637521706594157,
            0.000158810177173692,
            -0.00015822838180130038,
            -0.00015657870028851112,
            -0.0001502391851481768,
            -0.00014415776018484566,
            0.00014034870278860606,
            -0.00014004852288610823,
            -0.00013408222350771992,
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            -0.0001228621366070412,
            0.000121193518620545,
            -0.00011941660965319208,
            0.00010670562443295882,
            -0.00010205585575810493,
            -0.00010202862608405494,
            -0.00010191156736052748,
            -0.00010187347588176835,
            -0.00010164055970589437,
            -0.00010084278210008494,
            9.926652275837686e-05,
            -9.801405986273741e-05,
            9.498538291112192e-05,
            -9.056428470894562e-05,
            8.992158198610014e-05,
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            8.811696099222054e-05,
            8.397102446358522e-05,
            -6.306412977390877e-05,
            -6.076037214595889e-05,
            -6.071351709123079e-05,
            -5.9785198190737894e-05,
            -5.971256548131687e-05,
            5.960453517708301e-05,
            5.9334941964395615e-05,
            -5.867250468942376e-05,
            5.6100685930984804e-05,
            -5.3483063002944336e-05,
            5.302922648672534e-05,
            -5.1724590105742206e-05,
            5.0418419341039456e-05,
            -4.985752741116464e-05,
            4.969672458177316e-05,
            4.29430062347847e-05,
            -4.0855914185453704e-05,
            -3.984902540811548e-05,
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