Methods for performing affinity maturation and/or mutagenesis are described, for example, in U.S. Patent Numbers 7,195,880 ; 6,951,725 ; 7,078,197 ; 7,022,479 ; 5,922,545 ; 5,830,721 ; 5,605,793 , 5,830,650 ; 6,194,550 ; 6,699,658 ; 7,063,943 ; 5866344 and Patent Cooperation Treaty publication WO06023144 .

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