Danquah bɛyɛɛ mmrahyɛbedwani wɔ 1946 mu na ɔhwehwɛɛ kwan a wɔbɛhyehyɛ mmra ɛbɛboa ama Ghana enya faahodie. Ɔboaa sɛ wɔbɛtew kuw United Gold Coast Convention. Bere a Kwame Nkrumah fii amanɔne bae no, ɔdanee kuw no yɛɛ amanyɔkuw. Wɔ 1946 mu no, tumi ho mansotwe kakraa tuu UGCC ase na Nkrumah tew ne ho kɔtew Convention People's Party (CPP). Wɔde Danquah ne Nkrumah kɔɔ fie ase wɔ 1948 mu, na eyi maa amanfo nyinaa de obuo maa wɔn. Wɔsan tow aba paw Danquah kɔɔ mmrahyɛbedwa nkyekyɛmu abien a wɔbɛyɛ "House of Representatives" ne "House of Elders". Eyi amma so saa no, Danquah annonyam nyinaa brɛɛ ase. Abatoɔ a ɛbaa so wɔ 1954 ne 1956 mu nyina ankɔ yiye amma no.