Njira yachitatu ndi kudzera mu ntchito ya chiwindi. Zochita za chiwindi, Symlin amagwira ntchito poletsa kapena kuchepetsa kutuluka kwa glucagon ndi maphala. Iyi ndi hormone yomwe imayenera kumasula shuga m'magazi. Glucagon imathandiza chiwindi pakatembenuka kwa glycogen kuti shuga. Pa matenda a shuga omwe ali ndi mitsempha yambiri yamagazi, Symlin amathandiza kuthetsa vutoli polepheretsa kutuluka kwa shuga kwambiri pogwiritsa ntchito glucagon.