Rats da JNJ-1661010 (20 mg / kg ip) yana da Cmax na 26.9 μM plasma a Tmax na 0.75 h da Cmax a kwakwalwa ta 6.04 μM a Tmax na 2 h. JNJ-1661010 (20 mg / kg ip) ya hana kwakwalwa ta FAAH kuma ya haɓaka matakin AEA a kwakwalwar nama a cikin bera.