80aa785e__Universal___Life_Technologies__Possible_Solution
[Problem] The complex is unusually large and is difficult to handle.. [Cause] This indicates that there is a large amount of DNA present. [Possible Solution] 
Refer to sample pre-treatment Refer to advice on handling the DNA/Dynabeads complex If the problem persists, either use less sample or more Dynabeads.
Dynabeads® DNA DIRECT™ Universal | Life Technologies