57d50aa9_Health_Information_Library__Why
[Used for] 1 Star Kidney Stones Refer to label instructions [Why] 
Taking vitamin B6 with magnesium can inhibit oxalate stone formation. Both magnesium and vitamin B6 are used by the body to convert oxalate into other substances. Vitamin B6 deficiency leads to an increase in kidney stones as a result of elevated urinary oxalate.202 Vitamin B6 is also known to reduce elevated urinary oxalate in some stone formers who are not necessarily B6 deficient.203 , 204 Years ago, the Merck Manual recommended 100-200 mg of vitamin B6 and 200 mg of magnesium per day for some kidney stone formers with elevated urinary oxalate.205 Most trials have shown that supplementing with magnesium206 , 207 , 208 and/or vitamin B6209 , 210 significantly lowers the risk of forming kidney stones. Results have varied from only a slight reduction in recurrences211 to a greater than 90% decrease in recurrences.212 Optimal supplemental levels of vitamin B6 and magnesium for people with kidney stones remain unknown. Some doctors advise 200-400 mg per day of magnesium. While the effective intake of vitamin B6 appears to be as low as 10-50 mg per day, certain people with elevated urinary oxalate may require much higher amounts, and therefore require medical supervision. In some cases, as much as 1,000 mg of vitamin B6 per day (a potentially toxic level) has been used successfully.213 Doctors who do advocate use of magnesium for people with a history of stone formation generally suggest the use of magnesium citrate because citrate itself reduces kidney stone recurrences. As with calcium supplementation, it appears important to take magnesium with meals in order for it to reduce kidney stone risks by lowering urinary oxalate.214
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