f6098d8b__and_Use_of_Laboratory_Animals__Comments
[ID] 508 [Entry Date] 04/25/2011 at 06:26:09 PM [Affiliation] Self [Comments] 
Comment 1: I understand that one proposal is to mandate the use of pharmaceutical-grade chemicals ("when available, for all animal-related procedures") and that use of non-pharmaceutical-grade substances would need to be described and justified in IACUC protocols. I wonder if this is advantageous given the limited evidence that using pharmaceutical grade drugs would improve animal welfare or science. In addition adjustment of dose could be problematic since pharmaceutical grade drugs are single concentration formulations.
Listing of Public Comments on Proposed Adoption and Implementation of the Eighth Edition of the Guide for the Care and Use of Laboratory Animals