0ba0c9c5_t_Red_104___Environment_Canada_Summary_table_Response
[Topic] Effects on wildlife [Comment] Water is the most likely candidate for contamination from application and post application releases but they were not quantified. The commenter also stated that no estimate data were provided to assess impacts to aquatic wildlife species or the quality of water from sewer systems. [Response] 
A reasonable worst-case exposure scenario for the receiving water bodies and the aquatic organisms showed that the substances were not found to cause acute aquatic ecotoxic effects. It is also unlikely that terrestrial wildlife or other organisms living in other compartments (e.g. soils/sediments) would be harmed by exposure to this substance or by contaminated food considering the low solubility of these pigments. A quantitative estimation of risks, including the calculation of exposure concentrations and risk quotients was thus not warranted considering the properties of these pigments (particularly their low solubility). Furthermore, the particles containing these pigments may be removed during sewage treatment. The low solubility of the pigments would prevent dissolution of the pigments, leading to extremely low concentrations of dissolved metals from this source.
Public comments for C.I. Pigment Red 104 - Environment Canada