57d50aa9_Health_Information_Library__Why
[Used for] 3 Stars High Homocysteine (Folic Acid, Vitamin B12) 400 to 1,000 mcg of folic acid daily, 10 to 50 mg of vitamin B6 daily, and 50 to 300 mcg of vitamin B12 daily [Why] 
Vitamin B6, folic acid, and vitamin B12 all play a role in converting homocysteine to other substances within the body and have consistently lowered homocysteine levels in trials. Vitamin B6, folic acid , and vitamin B12 all play a role in converting homocysteine to other substances within the body. By so doing, they consistently lower homocysteine levels in research trials,23 , 24 , 25 a finding that is now well accepted. Several studies have used (and some doctors recommend) 400-1,000 mcg of folic acid per day, 10-50 mg of vitamin B6 per day, and 50-300 mcg of vitamin B12 per day. Of these three vitamins, folic acid supplementation lowers homocysteine levels the most for the average person.26 , 27 It also effectively lowers homocysteine in people on kidney dialysis.28 In 1996, the FDA required that all enriched flour, rice, pasta, cornmeal, and other grain products contain 140 mcg of folic acid per 3½ ounces.29 This level of fortification has led to a measurable decrease in homocysteine levels.30 However, even higher levels of food fortification with folic acid have been reported to be more effective in lowering homocysteine,31 suggesting that the FDA-mandated supplementation is inadequate to optimally protect people against high homocysteine levels. Therefore, people wishing to lower their homocysteine levels should continue to take folic acid supplements despite the FDA-mandated fortification program.
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