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Showing posts from July, 2008

The war still claims victims

A tragic story in today's La Prensa Grafica. A little girl found an old grenade in a gully by her home. She took the grenade home to show her mother. In the house the grenade fell from her hands and exploded killing a 60 year old man in the house as well as two children and another adult. This follows only 4 weeks after a similar incident in which a child found a mine or a grenade, which exploded and injured 4 children in Chalatenango.

These children are the tiny victims of a war fought before they were born.

The Monument to Memory and Truth

The Los Angeles Times published a recent story concerning the Monument to El Salvador's civillian war victims, located in Cuscatlan Park in San Salvador:
Engraved with nearly 30,000 names, the Monument to Memory and Truth is a roll of dead and disappeared from the conflict, which ended in 1992. It is incomplete. Officially, the fighting between leftist guerrillas and the right-wing military government killed 75,000 and left thousands more missing. Not all the names of the war's victims were available when the monument project began, so the list is growing.

The monument, erected five years ago by the city's leftist-run government, draws visitors from around the country to mourn loved ones confirmed killed in the political violence or, in many cases, who have simply vanished.

An engraved name on this glinting stone is often the closest thing to a proper grave site many people will have. The neat rows of names represent bits of history, fibers of memory, personal anguish.

The ongoing debate over the ILEA

Organizations which advocate for human rights in El Salvador continue to differ over the US-run International Law Enforcement Academy (ILEA). At the ILEA, law enforcement instructors from the US teach courses to police, judges and prosecutors from El Salvador and the rest of Latin America. The courses taught at the ILEA cover topics such as trafficking in persons, anti-gang activities, drug crimes and crime scene management. I have previously expressed my support of the ILEA concept.

The most recent embodiment of the debate over the ILEA began with an article in the NACLA Report on the Americas by Wes Enzinna, a UC-Berkley graduate student in Latin American Studies and freelance journalist. Enzinna's article contains a variety of attacks against the ILEA including the refusal of the school to release its list of graduates or its training materials, the opposition of Salvadoran human rights groups, the clear human rights abuses of El Salvador's National Police, statements b…

El Salvador's National Soccer Team

There's a nice article on the website of FIFA with an interview with Carlos de los Cobos, coach of El Salvador's national soccer team:
El Salvador's win over Panama last month in the North, Central American and Caribbean zone qualifiers for the 2010 FIFA World Cup South Africa™ was one of the biggest shocks of the preliminary competition so far. Ranked 60 places below the Canaleros in the FIFA/Coca-Cola World Ranking, the Cuscatlecos were not expected to unduly trouble their Central American cousins, and not even their own fans held out much hope of victory.

However, no one gave the script to Carlos de los Cobos' men who, after a narrow 1-0 defeat in Panama, turned the tie around with a magnificent 3-1 win in San Salvador to progress to the first group phase of CONCACAF qualifying. So how did they do it? In an exclusive interview with, their Mexican coach gives his take on the resurgence of Salvadoran football.

More than anyone, De los Cobos knows the difficul…

Dynamite fishing threatens sea turtles

Environmentalists in El Salvador are seeking international support in their efforts to combat fishermen who are using dynamite to fish in some of El Salvador's environmentally sensitive waters. I came across this plea for help on the website of Deep Sea News :

In an alarming trend, the practice of "dynamite" or "bomb" fishing has spread recently to Central America. Reports are coming in that hawksbill turtles are being blasted to death by explosive fishermen working in the Biosphere Reserve of the Bahia de Jiquilisco, El Salvador. At least seven turtles have been found dead, according to Michael Liles, Sea Turtle Conservation Project Coordinator for Fundacion Zoologica de El Salvador (FUNZEL). The use of explosives is exterminating all species of larvae, juvenile and adult fish, as well as crustaceous, mollusks, sea turtles, and other species of organism living throughout the Bahia de Jiquilisco.The practice spread from Southeast Asia, where dynamite fishing is…

UN report on jobs in El Salvador

Last week the United Nations Development Program issued an important report for understanding the economic situation facing El Salvador's families. The Report of Human Development in El Salvador 2007-08 presents a comprehensive overview of the job situation in the country:
El Salvador is a country of workers. Not only because almost everyone has to work in order to earn their daily sustenance, but also because of the fame of its inhabitants as workers. The industriousness and enterprising nature are so deeply rooted in the Salvadoran identity that more than half of the population considers that "to be Salvadoran" is to be hard working.

However, the work situation is far from being satisfactory for the majority of persons. This report has determined that when the greater part of the population complain that the country is either bad or very bad with respect to employment, it refers to the fact that there are very few opportunities for "dignified work." Dign…

Travellers in El Salvador

It's summer, so people are traveling to El Salvador and blogging about their experiences. Aaron and Lyndi, the Texas nomads, pretty much sum up what they and others have found:
The fact of the matter is this: this country is beautiful, with some of the most friendly and helpful people I've met not on this journey but in my life, and with mountains, waterfalls, food festivals, great art and music scene, and killer surfing- it boasts just as much as the other C.A. countries. And if that doesn't draw you in, I need only say one word: Pupusas.
Read their blog entries about Santa Ana and El Zonte.

Other travelling bloggers include Alyssa Schwartz who is currently blogging from a service trip to El Salvador, and Nin Andrews who blogs as she visits her Peace Corps Volunteer daughter. Meanwhile Vanessa Nguyen arrived in San Salvador yesterday and writes about her travels in her blog Jungle Guerrilla Roadie.

Disability rights in El Salvador

Larissa Hotra, a Peace Fellow of the Advocacy Project working in El Salvador, has written an article on the site Upside Down World titled A Recent History of the Disability Rights Movement in El Salvador. Here's the introduction to the article:
Many argue that El Salvador has come a long way towards trying to repair its disabled past by declaring itself mine-free in 1994, implementing the 2001 National Disability Rights law and ratifying the United Nations Convention on the Rights of Persons with Disabilities in 2007. The Permanent Table of the Office of the Ombudsman for Human Rights (PDDH) and disability rights civil society organizations such as the Landmine Survivors Network have led the struggle in Central America to promote the rights of people with disabilities and guarantee them “free and equal access to services” through the construction of accessible infrastructure and much-needed legislation.

And yet, El Salvador has only made nominal progress in implementing disability…

Two documentaries to watch for

Two upcoming documentaries will feature life in El Salvador, up close and personal.

The first is Las Chulas. From the website of the film maker Rattle Can Films:
Las Chulas is a character-driven documentary about coming of age and finding a place in post-Civil War El Salvador. The story follows the lives of three unique young girls; Maria, Yoselin, and Erika, as they face the challenges of growing up in a country rife with gang violence, drugs, and poverty. Living in a small beach community, the girls discover surfing and with it, a newfound sense of their own potential and the possibilities of a life beyond the everyday despair that threatens to smother them.
Second is La Vida Loca, a film by Christian Poveda. From this film's website:
Filmed in close-up using a hand-held camera, this will be La vida Loca, the crazy life, as the pandilleros say. For a year, the camera will focus on daily life in a base cell of one of the gigantic maras, the la Campanera MS-18 clique, composed of f…

Viewing the economy

Here is a set of contrasting views about the economic situation in El Salvador. First, the view of the ARENA government as described in an article from the Washington Times on July 17:
Vice Minister for Foreign Affairs Eduardo Calix appears not overly worried. He recently noted that "the election is still a long way off" and finds it difficult to believe a majority of voters will back the FMLN. "The election will be a battle between our democratic system and their revolutionary system, at a time when the country is having unprecedented peace and prosperity. Backed by Venezuela and others, the FMLN want to completely change our economic and social system.

"It will be a passionate campaign," Mr. Cadiz acknowledges, "but the FMLN cannot ignore the improvement in the lives of most citizens over the past several years, and they cannot resort, as before, to violence - the government will not permit it. El Salvador enjoys political security and a solid financial…

Salvadoran diplomats saved thousands of Jews from Holocaust

A lengthy article article in the Washington Post this week recounts events in history I have mentioned before, where Salvadoran diplomats during World War II were responsible for saving the lives of thousands of Jews from Nazi extermination camps:
On government business in Europe before the war, Castellanos meets George Mandel. The war starts. Castellanos is posted to a succession of European cities as a diplomat. With Nazi tanks overrunning the continent, Mandel, as a Jew, knows he's in peril and turns to his friend. Castellanos makes Mandel an honorary Salvadoran diplomat and gives him a Salvadoran passport. Mandel changes his name to Mandel-Mantello, to give it a more Latin ring. Castellanos issues Salvadoran visas to other European Jews.

By 1942, Castellanos becomes the Salvadoran General Consul in Geneva and appoints Mandel-Mantello the consulate's "first secretary," a fictitious title that does not exist in the Salvadoran diplomatic hierarchy.

Mandel-Mantello p…

Rodrigo Ávila's grand crusade

Some 50,000 ARENA supporters, dressed in the tri-color red, white and blue of their party, converged on Cuscatlan Stadium in San Salvador on Sunday. Billed as the "Grand Crusade for San Salvador," ARENA wanted to show that it could turn out crowds for its presidential candidate Rodrigo Ávila as large as those following Mauricio Funes. (El Faroraised doubts about Sunday's crowd when it reported that many government ministries conveyed the "suggestion" to their employees that they should turn out for the ARENA rally).

One of the biggest questions about Rodrigo Ávila's campaign is who will be his vice-presidential running-mate. Current predictions are that it will be Arturo Zablah, the businessman, ex-minister of the economy, who tried to run for El Salvador's presidency as a candidate in the center earlier this year but was unable to pull together a coalition. Negotiations between Zablah and Avila are reportedly in progress, with Zablah asking for ce…

El Salvador officials urge expats to invest

Local officials from El Salvador are touring communities of Salvadorans living abroad, looking for investment in local communities as described in this story in the Boston Globe:Nearly a dozen mayors, city councilors, and town administrators from the Central American nation swept through Massachusetts during the past two weeks to urge immigrants to invest in their homelands, create jobs, and - ultimately - prevent Salvadorans from having to immigrate to the United States for work.

About 1 million Salvadorans now live in the United States, including more than 17,000 in Massachusetts. The mayors are reaching out directly to émigrés as part of a new government-sponsored program, asking them to form committees or invest on their own.

Salvadoran immigrants already send home $3.3 billion a year, and nearly 30 percent of adults in El Salvador depend on the money to cover basic needs such as food, clothing, and shelter, according to the Inter-American Development Bank in Washington. The money h…

Considering gold mining permits

In my post titled How Pacific Rim has been treated, I raised a series of questions about the process. Roddy Hughes at Voices on the Border provided me with a set of thoughtful responses to those questions which I reproduce here:

1. Pacific Rim has apparently provided (I have not seen it) an environmental impact assessment which it believes shows that the environmental risks will be minimal. Shouldn't Pacific Rim be allowed a fair hearing on that environmental impact statement? If it has not been given that fair hearing, why not? If it has not had a fair hearing, what is the message which El Salvador is sending to those who might want to invest in the country in the future?

A few years ago Pacific Rim filed an environmental impact statement with the Ministry. It was a half-hearted effort to satisfy requirements under the law on the environment and the law on mining. The government, in an equally half-hearted manner, complied with their requirement to make the EIS available fo…

Visiting El Mozote

One week ago, I visited El Mozote in Morazan department, El Salvador for the first time. In the years before this visit, I had read many accounts of the massacre which occurred there in December 1981 including the initial story reported by Raymond Bonner in the New York Times, the UN truth commission report followng the war, Mark Danner's book The Massacre at El Mozote and Danner's article The Truth of El Mozote in the New Yorker. I have also watched video of Rufina Amaya, the sole survivor of the massacre, providing her testimony. More than 1000 civilians were killed by the Alcatl Battalion of the Salvadoran armed forces.

So intellectually I knew what had occurred almost 27 years ago, but the impact of actually being at the site of such horror was powerful. Particularly heart-wrenching is the Garden of the Innocents, next to the restored church, where the remains of 146 children are buried. There names and ages are inscribed on plaques on the wall of the church, from 3 …

Rains bring tragedy and challenges

A tragic loss of life last week brought renewed focus on the need for government bodies in El Salvador to act on infrastructure projects to reduce flooding and other risks. Last Thursday night, 31 members of El Salvador's Elim Church were drowned as their bus was swept into a raging river current and smashed against a bridge pylon.

In a fierce thunderstorm that night, more than 5 inches (128mm) of rain fell, and the river Acelhuate overflowed its banks. The torrent caught the bus full of worshipers from the large evangelical church and pulled it into the river's concrete channel. A camera and video team from El Diario de Hoy just happened to be in the exact area and caught the last moments of the bus on video.

Through the following days, the press was filled with reports of the grieving families, the story of the one survivor, and the search for bodies which were carried by the river's current all the way to Chalatenango.

Many sought answers for the cause of the tragedy. …

Gilberto Soto murder still has open questions

I had the pleasure of meeting with Ernesto Rivas Gallont when I was in San Salvador last week. He was El Salvador's ambassador to the US during the 1980's, and now is a newspaper columnist, blogger, and wise observer of current events in the country. I'll be touching on some of the topics we discussed in upcoming posts.

In Don Ernesto's regular Sunday column in La Prensa Grafica this Sunday, he brought up the still unresolved (except in the view of the PNC) case of Gilberto Soto. Soto was a Teamsters union organizer from the US who was killed while visiting his mother in El Salvador. The column includes the text of a letter to president Tony Saca from US Senator Patrick Leahy of Vermont, pushing for a reopened investigation into the Soto murder:
According to information I have received, a recent motion in the National Assembly which called for a new investigation of the Soto case was opposed, and defeated, by your government. This concerns me, and I urge you to re…

How Pacific Rim has been treated

Following the announcement from Canadian gold-mining company Pacific Rim that it was suspending its efforts to develop a gold mine in El Salvador, the website MineWeb published an article with a long discussion with Pacific Rim's president, Tom Shrake:
Pacific Rim has put up with destruction of property, threats on the lives of its employees, and frightened witnesses who refuse to testify against the perpetrators. Ironically, the environmental quality of the project isn't a serious point of contention. An Inco process will oxidize and destroy any cyanide used in the operation. A water treatment plant will treat all water discharge from the operations. Water quality is so optimal at the site that a tailings pond can eventually safely serve as a reservoir for local communities. And, Shrake noted that there is no acid generation potential at El Dorado.

Shrake does not even suggest that El Salvador's Government is in any way corrupt or incompetent. Nevertheless, he asserted th…

Gold mining company Pacific Rim cuts operations in El Salvador

Canadian gold mining company, Pacific Rim is blaming an anti-mining atmosphere and politics for its decision to suspend drilling operations and lay off workers in El Salvador according to reports today:
TORONTO, July 3 (Reuters) - Pacific Rim Mining has cut its work force and suspended drilling in El Salvador due to frustration over a lengthy permitting process for its El Dorado gold mine, the Canadian company said on Thursday, sending its stock down by 34 percent. However, the company will not abandon the assets and has ruled out selling them, Chief Executive Thomas Shrake said in an interview. El Dorado "is a very attractive mine, high margin, environmentally solid, and the other projects that we have just have extremely high odds of success," he said. In addition to El Dorado, Pacific Rim owns the Santa Rita and Zamora gold projects in the Central American country. It also owns a 49 percent interest in the Denton-Rawhide gold mine in Nevada, as well as the Carrera and Col…

Crime statistics

I used to blog almost monthly about murder statistics in El Salvador. I stopped doing it so regularly because (a) it was depressing and (b) some criticized me for giving El Salvador a bad name and potentially scaring off people who might want to visit. Still, since violent crime is one of the number one worries of Salvadorans, it worth looking at the most recent statistics, as published in El Mundo:
There were 1279 murders through May 2008, or approximately 8.5 per day. The departments with the fewest murders are Chaletenango and Morazan.Almost 90% of the victims are male and almost 70% are between the ages of 15 and 34.160 municipalities have registered at least one homicide, while 102 have not seen a murder this year. The national homicide rate is 60.9 murders per 100,000 inhabitants. The most violent municipality is Quezaltepeque with a homicide rate of 175 per 100,000.It's still depressing.


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St Mary’s Sabden 80 yrs anniversary

ST MARY’S SABDEN celebrates 80 years this year. To celebrate the occasion there is to be a Flower Festival over the weekend 20/22 October together with other events. Two posters and a letter are on the notice board. Please note the request for any local archive material, church related or not, and do support the events as you are able. I am proposing to sponsor a flower arrangement on behalf of the parish.

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12 December 2013

Well, in my opinion, definitely one of the best gift ideas ever.  And it's under £15!  Last Christmas I bought a few copies of illustrator-turned-writer Lou Beach's 420 Characters to give to friends, after reading the series of imaginative, funny, poignant, surreal, intriguing short stories and (420-character) prose about peculiar little worlds, relationships and characters and feeling compelled to share.  It's on Amazon in book and kindle form, but here are my favourites for a little preview.

Lou Beach 420 Characters book of short stories

"Are you my mommy?" said the little blue egg. "No dear. You are a plastic trinket full of sweets," said the brown hen. "My baby is over there", and she pointed to a pink marshmallow chic being torn apart and devoured by a toddler.  The hen screamed and woke up, her pillow wet with sweat, the sheets twisted around her legs. "Christ, I hate that dream." She reached for a smoke.

A bird lives on my head, nests in my hair, pecks at my scalp.  A finch, I believe.  When I go out in public I cover it with a hat, so it's away from prying eyes and cats who would climb my body to catch it.  Sometimes on the bus I notice others wearing hats, and if there are seeds or an errant feather on their shoulders, I nod and smile and preen.

She was indiscriminate in her taste for jewellery.  Paste, carats, costume, it was all glam flocking.  She was like a magpie, hoarding sparkles in a box.  Every day she put on earrings, necklaces, brooches, bangles, bracelets, and pins, none of which matched; an upended Christmas display held together by some hair and a dress from the bottom of a closet with a burned-out light.

I lay the book on the floor, open to the middle.  It's a lovely volume, green leather covers engraved endpapers.  I remove my shoes and step into it up to my ankles, knees, hips, chest, until only my head is showing and the pages spread around me and the words bob up and down and bump into my neck, and the punctuation sticks to my chin and cheeks so that I look like I need a shave.

The house was tucked into the bottom of a cul-de-sac, surrounded by a high brick wall. One of the bricks was missing and in the cavity lived a tiny man, Ray.  He shared the space with a finch, a lovely lady from Indiana, Jill.  She often gabe Ray rides to the drugstore so he could pick up his medication, and he in turn constructed a nest for Jill out of cotton from his prescription bottles.  There was no hanky-panky.

The oak table, set for twelve with bone white china and crystal goblets full of sparkling water, glistening silverware, was sprouting lettuce.  It pushed out of the worn wood, knocked over the glasses, spilled water that irrigated the new growth.  Plates were overturned by root vegetables pushing upward, silverware sent scattering by tomato vines and beanstalks until the entire table was a victorious garden.

I live in the pocket of a bright paisley shirt - silk - and when the light is just so, I'm in my own private cathedral. I lie back and push out against the fabric with my feet, and the coloured light falls in like kids' breakfast cereal.  I lived in a canvas shirt once but the guy was always sweating so much it recalled that tent in Ireland near the sea where I first got this assignment.

There was a man on my lawn.  I saw him through the window.  He was sitting with his legs straight out in front of him, hands in lap, back very erect.  I armed myself with a baseball bat, went outside.  "What are you doing here?" I said.  He smiled and said: "I am Right Angle Man."  Relieved that he was harmless, I laughed and said: "Where is your cape?"  He looked up at me.  "I am not a superhero.  Are you with the Yankees?"

Her summer dress is crisp, white with dark blue polka dots, open at the throat, sleeveless, set off by a wide red leather patent belt and espadrilles that raise her heels three inches from the sticky tarpaper.  Backlit by the sun, her hair a splendour, she walks to the edge of the roof garden, looks down for a moment at the street sixty stories below, then returns to water the tomato plants.  There are no insects up here.

Years back the river overflowed, flooding a nearby apple orchard.  Grandpa was sitting on the high front porch watching the water rushing down the street when he saw a flotilla of apples bobbing past.  He quickly got his waders and proceeded to fish for fruit.  Grandma made pies and apple sauce and fritters for weeks.  That's how the local saying "When the river rises, make fritters" comes about.  That's the origin, true story.

Hot in the bait shop today.  Guy walks in, all big city, Jew hair, glasses.  I'm thinking, only thing he's ever fished for is a compliment.  "Can I help you?"  "Yes, would you happen to carry any Yamamoto 9S Senko freshwater lures in a four inch?"  Man, I felt there was shit on my shoe.  The dude was DEEP."

"The new swim coach is really nice, Daddy.  He liks to give my neck and shoulders a massage when I get out of the pool."  She smiles at me, her hair still wet.  "Do you know the phone number of the PE Department at school?" I say.  "Oh, can we invite him over for dinner?"  I put the phone down.  "Do your homework, Daddy's going out for a while."

His hands jump into the bowl, the ground meat, to join the conversation going on with the raw egg, onions, the salt and pepper.  He squeezes it all through his fingers and wonders if his brain would feel like this if he grabbed it from behind.  Cooking calms him, makes him introspective.  This is Life, he thinks.  You put a lot of stuff together, smoosh it around, and pretty soon you've got a bunch of meatballs.

I open the can, press the oil out of the tuna with the lid.  I recall sandwiches you made, just the right amount of mayo, onions, celery, sourdough with lettuce or, if you were happy, alfafa sprouts.  In my reverie I don't notice that I've sliced my thumb with the lid and blood mingles with the oil and flows down the drain and pipes to a processing plant and to sea, to finally wash up on a beach where we once fished.

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Monday, 27 August 2018

E14 Endorsed: Talk Star Wars - Episode 133 | Ewok Gymnasium

It's Episode 133 of the Talk Star Wars podcast, and this week Rob and Brad discuss their thoughts on midichlorians and those who wield them, some thoughts on Episode IX and whether Vader should appear, the trailer for Resistance and the newly announced Zynga deal! Also, should Episode IX end the Skywalker saga? Find out their thoughts on the show!

If you want to get your questions read out on the show, why not email us at, tweet us @TalkStarWars or Like our Facebook page?

Talk Star Wars

The official podcast of The latest Star Wars, Rogue One, Episode VIII and Star Wars Rebels news and rumour.

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Cosmetic Dentistry – achieving a healthy smile

November 2017

In the modern age of social media, people are increasingly more aware of their appearances and how it impacts on their daily life. Modern dentistry has adapted to these increasing demands, with the development of various “tooth coloured” options for restoring teeth to their natural form and appearance.

The original white fillings which date back to the 1960’s had issues with strength and longevity. With the introduction of light curing, advances in bonding technology and the improvement in the composite resin material, white fillings, today have become a reliable alternative to silver amalgam fillings.

Dental crowns have also evolved over the years as cosmetic dentistry has become more important. Crowns originally were made from gold, but with the demand for something white, there was a move to porcelain fused to metal crowns. With these crowns, the metal provided underlying strength, whilst the porcelain provided for a white tooth-like appearance. However because there is metal under the porcelain there would sometimes be a dark shadow or ugly, black lines near the gum margin. Often the metal would become visible if the porcelain chipped or wore thin (see images below).

cosmetic dentistry - porcelain fused to metal crowns - black linecosmetic dentistry - porcelain fused to metal crowns with metal visible

At Dr Lester Mark’s dental practice in Endeavour Hills, most crowns today are made from a new material called e.max or lithium disilicate which is a glass ceramic. The advantages of this material are that it is has no metal, yet is strong, has very similar appearance to tooth enamel and can be bonded to the tooth. This allows the crown to be thinner than porcelain fused to metal crowns, which means less tooth structure needs to be cut away when preparing the tooth. This results in a stronger tooth in the long term.

“Preservation of tooth structure is the ultimate goal in modern dentistry.”

As these crowns have no metal, they are more translucent than porcelain fused to metal crowns and  have a more natural appearance.

cosmetic dentistry - e.max crownscosmetic dentistry - porcelain crowns

Porcelain veneers have become fashionable in recent times as a longer lasting solution to chipped front teeth or fillings. They can replicate the natural appearance of worn, decayed or broken teeth and can also help to align some minor crowding or crooked teeth to improve their appearance.

Cosmetic dentistry is not just about teeth. The gums and their appearance are also an important part of a healthy looking smile. It is important to maintain clean teeth and healthy gums through daily brushing and flossing as well as periodic professional cleaning. Diseased gums can look red, swollen and detach from the tooth, leaving unsightly black spaces.

Other important considerations in cosmetic dentistry today are advances in teeth whitening procedures and orthodontics, especially since the development of technologies like Invisalign.

For enquiries about cosmetic dentistry whether it be about white fillings, porcelain crowns, porcelain veneers, onlays, bridges, teeth whitening or orthodontics, please call Dr Lester Mark’s dental practice in Endeavour Hills on 9700 6088 to make an appointment for a consultation.

You can’t blame tooth decay on your genes, twin study shows

September 2017

If you’re a frequent visitor to the dentist’s chair, you may think you inherited bad teeth from your parents, but a new study of Australian twins shows you can’t blame your genes for tooth decay.

Teeth Whitening

August 2017

Teeth whitening has become a common treatment in recent years with much promotion in magazines and on social media.

But not all teeth whitening procedures are the same…………….

Lifestyle Risks and Oral Health

July 2017

If you’re like most people, the odds are good that your idea of a healthy lifestyle begins and ends with making sure you eat lots of fruit and vegetables, and get exercise as much as you can.

And while both of these factors are crucially important in keeping you fit and healthy, the reality is that your oral health, that is how good a state your teeth and gums are in, has a major effect on your overall health.

Do I need to remove my Wisdom Teeth?

June 2017

Wisdom teeth are the last permanent teeth to appear and are known as the third molars. They are positioned at the back of the jaws, and can appear as early as 16 years old or as late as 65 years old. Not everyone will have wisdom teeth but generally people have up to four wisdom teeth, two on the top jaw and two on the bottom jaw.

Mouthguards – What you need to know

April 2017

Teeth are at risk of serious damage when playing sport, and a knock to the mouth without a mouthguard can result in broken teeth and injuries to the lips, tongue, face or jaw. Mouthguards help cushion blows that cause these injuries and can reduce the incidence and severity of concussion.

There are two specific types of mouthguards, the custom fitted mouthguard (pictured below) and the ‘boil-and-bite’ or ‘over the counter’ mouthguard.

Continuing Professional Development – Keeping up to date with the latest dental research and techniques

March 2017

After more than 20 years practising as a dentist, it is easy to become set in one’s ways. But dentistry is constantly changing with new techniques, new materials and a plethora of research to keep up to date with. Dr Lester Mark has a passion for continuing education and believes in life long learning, having been a member of the ADA (Vic Branch) Continuing Professional Development Committee for more than 10 years.

New Research links Gum Disease and Heart Disease

February 2017

Recent research from the USA has found that people with gum disease are twice as likely to have heart disease, and may be at an even greater risk than those with high cholesterol levels.

Medicare Child Dental Benefits Schedule (CDBS) to continue into 2017

January 2017

Following several months of uncertainty regarding the future of the Medicare Child Dental Benefit Schedule (CDBS), the Federal Government announced in late December 2016 that the scheme will be continuing into 2017 in a somewhat different form.

medicare child dental benefits schedule


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Arnâron – Nations and the Balance of Power

I’m still working on Arnâron (and I do wonder if anybody actually keeps up with the pace… well, no matter.) I’ve started to give some thought to the layout of the nations, and the balance of power between them.

Let’s first consider the geography and national borders. I haven’t given the nations names yet, so they’ll just be referenced by letter, like so:

Nations of Arnâron

Now, let’s take a look at each nation in turn.

Nation A: Temperate weather (for Arnâron), meltwater from the polar cap replenishes the sea every year in the local summer. The downside is flooding and marshland in the north-eastern part of the country. Expansion to the west is limited by extended salt flats (not shown on this map, but refer to an earlier map for a rough idea of where it’s located). Nation A is very close to Nation B, but separated by geography: Mountain ranges and marrow chasms make any overland assault on the neighbor a deadly exercise. This doesn’t mean they’re not trying. Both nations have relatively high birth rates and each is constantly worried that the other may decide it needs the arable land of the neighbor to support its population. They live in an uneasy peace interrupted by frequent short, and very boody, wars that rarely affect a change in the borders. Nation A isn’t too worried about the other nations, as it enjoys relative geographic isolation.

Nation B: This nation benefits from what little precipitation exists on Arnâron. Hot, humid air from the equatorial regions hits the mountain ranges and rains off in the highest parts of the mountain. The water then flows downhill in rivers – a rare sight on Arnâron – and collects in a small basin at the center of Nation B. This nation has probably the best arable land on the planet, and it guards it jealously. Its conflic twith Nation A is constant but usually low-key, for further detail, refer to Nation A. Nation B keeps good relations with nations G and H, which it considers a buffer to Nation C, and good trade relations with nation J, via the functional long-distance canal that connects the two.

Nation C: Draws its qater supplies from melt-water from the southern pole. Its rules are highly expansionist, believing firmly that the best defense is a good offense, and that only the strong have a right to survive. It sees nation D as a constant threat, but assaults across the desert are difficult. This doesn’t stop either nation from trying – and the two countries are in a constant state of war. Nation C sees the nearby city-states K, G and H as part of its territory and hopes that conquering them will help give it an edge over the larged nation D. It is less concered with nation J, which is separated from it by a vast desert. Nations K, G, and H do not wish to become part of nation C, which they see as barbaric and cruel and so the three have formed a loose alliance to defend against nation C.

Nation D: The people of nation D would be very happy to keep to themselves, but unfortunately their neighbors have different ideas. Nation C is waging a constant war against nation D, but thanks to nation D’s superior numbers it was able to repel all attacks. Nation D, however, does not have sufficient numbers to attack nation C in a decisive manner without leaving itself open to the threat from nation F, which is attempting to expand southward.

Nation E: Nation E enjoys almost total isolation and a good supply of water from the northern polar cap. Little is known about this nation in the rest of Arnâron, and rumors abound.

Nation F: Located at the equator, Nation F suffers greatly from the climate and its agriculture has a very low output. Nation F is attempting to expand westward, along the equatorial river, but has so far encountered stiff resistance from barbarians and “monsters”. It is in no position to mount an offensive against nation A in the far north, and so it attempts to wage an asymetrical war against nation D to the south. The lake/sea in between the two nations is the main battleground of the conflict. Nation F does not quite realize that Nation D could easily wipe it out if it somehow can keep nation C from taking advantage of the situation; and has mostly opted not to do so on moral grounds. Ironically, nation D would probably happily help nation F out with food etc if only nation F attempted diplomacy for a change…

Nation G: Maintains good relation with nation B and H, and is constantly under threat from nation C. Nation H is a buffer between G and C, and since G knows it will be next in line as soon as H falls, nation G will support nation H (almost) unconditionally against any attack from nation C. Together with H, it maintains a loose alliance with K, which is difficult because of the distance separating the two; but G and H will attack C’s northern border if C attacks K and so the balance of power has been kept, for now.

Nation H: Heavily defended, heavily fortified, and heavily armed – this nation only knows one way of life: War. Not by choice, but out of necessity. Nation C is a constant threat. The citizens of H have perfected their defense over the decades and have attained a reputation as fearsome warriors as a result. The soldiers of H like to boast that the gods ended their destruction of Arnâron when they came across the armies of nation H; but of course this is nonsense, considering H was built on the ancient seabed. Still, the fact that they get away with such a boast without ridicule says a lot about these hardy people.

Nation J: Nation J is isolated from its neighbours by vast deserts. Unlike nation E, however, it is connected by functional long distance canals to two of them; nations B and D. It maintains lively trade with both of them, and benefits from all trade passing between D and B as it must go through J’s city. The citizens of J, consequently, have a reputation as successful traders and merchants. Nation J is doing quite well for itself, but any change in the political situation in either nation B or D would potentially mean trouble for nation J and so it is constantly attempting to foster a neutral status.

Nation K: This small, independent nation maintains a defensive alliance with G and H to ward off attacks from C. Unfortunately, it is quite isolated, and so troops from G and H can not aid nation K directly. Usually, G and H will attack C to prevent nation C from committing enough troops to conquer nation K. However, nation K’s location and relative weakness means that it is only a matter of time before nation K will fall. The rulers realize this, of course, and are desperately trying to find a solution for their predicament.

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2 thoughts on “Arnâron – Nations and the Balance of Power

  1. I've been looking over several of the WBM participants, and I have to say your world is one of the most in-depth I have come across.

    I'm constantly amazed at how much thought goes into these worlds you guys (general, inc. gals) create.

    Nice job, Nils. Keep it up and give them all (not me, you have read how I wander pretty much aimlessly) a run for their money.

  2. Aw, thanks.

    Wandering aimlessly… I do that a lot. You should see the notes section in my world building documents folder… 🙂

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#TravelTuesday with Regina Kyle

Sep 4, 2018 by

New York City

Okay, so pretty much everyone knows the Big Apple is a great travel destination. But with five boroughs to explore, there’s way more to see than the usual suspects, like the Empire State Building, Statue of Liberty, and Times Square. In Billionaire In Her Bed, Brooke shows Eli some of her favorite, lesser known spots. The Brooklyn Flea Market. The Prospect Park Zoo. And he takes her somewhere she’s never been: the Sunshine Laundromat, a real-life laundromat in Greenpoint, Brooklyn, with a secret room filled with vintage pinball machines you can play for a mere $0.75 per game.

That’s right, not everything in NYC is expensive. I live not too far from the City That Never Sleeps, and I spent years schlepping my daughter, a musical theater kid, in and out for auditions. (It paid off because she eventually booked the national tour of Mary Poppins, but that’s another story.) Together, we discovered lots of fun things to do on a budget. Like browsing at Mood, the fabric store made famous by the TV show Project Runway. You never know, you might even run into one of the contestants. Or Swatch, the store’s adorable mascot.

Feel like getting out on the water? Some of the best views of Manhattan are from the rivers surrounding the island. You can ride the Staten Island Ferry for free. Or you can rent a kayak for twenty minutes at no charge from May through mid-September at the Downtown Boathouse, a volunteer-run nonprofit on Pier 96.

Need a good laugh? The Upright Citizen’s Brigade Theatre, the comedy mecca started by Amy Poehler, recently moved to Hell’s Kitchen, right in the heart of Manhattan. You can watch future SNL cast members without breaking the bank, usually around 10 to 12 bucks.

You know the old saying about how to get to Carnegie Hall? Practice, practice, practice. Or show up on the day of the performance with a 10-dollar bill in your pocket. You can see all types of music, from folk bands to chamber orchestras to piano concertos.

That’s just a fraction of the fun you can have in New York City at bargain basement prices. Hotel heiress Brooke and real estate mogul Eli may not have been on a budget. But if you are, don’t be afraid to take the plunge and visit the Big Apple. You won’t regret it. And you don’t have to go broke doing it!

And while you’re at it – shameless plug alert – pick up The Billionaire In Her Bed while it’s only $0.99 and meet the loveably wacky residents of Candy Court.

Real estate mogul Eli Ward hasn’t had the best of luck lately–someone keeps stealing projects out from under him. So, with his new project, he’s keeping a low profile. Plus, he’s anticipating a fight from the somewhat eclectic folks currently living in the building. What he wasn’t anticipating was that the fight would be led by Brooke Worthington, the woman who absolutely rocked his world one unforgettable night. She might be the only woman in the city who doesn’t know who he is, which is refreshing…and tempting.

Graphic designer and part-time bartender Brooke Worthington is not interested in following her family’s plan for her. But she is interested in sharing a drink…and more…with a sexy stranger in a suit when her shift ends. The last thing she expects is to run into him again a few days later at a neighborhood meeting. Eli is hot, really hot, but she can’t afford distractions now that she has to save her building from some greedy real estate billionaire. Only, staying away isn’t as easy as she thought, especially when she learns exactly who Eli really is.

Regina Kyle also writes for Harlequin Blaze. She is a 2016 Booksellers’ Best Winner (Triple Dare – Erotic Romance) and a 2015 NJRW Golden Leaf Finalist (Triple Threat – Best First Book). Regina knew she was destined to be an author when she won a writing contest at age ten with a touching tale about a squirrel and a nut pie. By day, she writes dry legal briefs, representing the state in criminal appeals. At night, she writes steamy romance with heart and humor. A lover of all things theatrical, Regina lives on the Connecticut coast with her husband, teenage daughter and two melodramatic cats. When she’s not writing, she’s most likely singing, reading, cooking or watching bad reality television. She’s a member of Romance Writers of America and of her local RWA chapter.

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Hilton Hotels (2)

and the brand are logos or registered emblems of , LP within the U.S. and/or different international locations. All different emblems are property of their respective house owners.

Since World Battle II, the Congress has gone via many ownership teams, however has managed to outlive by sustaining a respectable stage of upkeep and being a low-value various to different hotels. The widening of Congress Parkway within the early nineteen fifties into the grand entrance to the town from Grant Park (as envisioned in Daniel Burnham’s 1909 Plan of Chicago) has only elevated the lodge’s desirable location.

This is pretty scary stuff. Every summer my mother in law and I journey to Florida and stay in hotels. We all the time try to get the bottom ground just to make carrying within the baggage easier. You might have certain opened my eyes in the case of Hotels and security. Thanks a lot I’m going to suggest to her to read your hub. Thanks for writing this to make many of us conscious.

We didn’t plan this stop very properly as we arrived in Gettysburg about 5pm on our method from Hershey, PA and our stop in Maryland just exterior of Washington DC. We stopped by a neighborhood visitor middle and they gave us a map of the area. We toured The Soldier’s Nationwide Cemetery at Gettysburg the place Abraham Lincoln gave the famous Gettysburg Tackle during the Cemetery dedication on November nineteenth, 1863. There is a monument devoted to Abraham Lincoln within the cemetary as nicely.

Because they’re lovely, entertaining and fun to be with. Would a middle age guy attempt to discover somebody his age in Costa Rica? They could assume that they’re very nice people, however of course they need money. Additionally, as in my case most girls dwell at home with their dad and mom until they marry and when my girlfriend’s father came upon he did not approve. However within the US girls my age had been also searching for security, so either way young or previous it is the same and no assure of love. An although I’m advised to take a facet I don’t fully agree with either.


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Fault-Tolerant Sensor Nodes With Erlang/OTP And Arduino

Kenji Rikitake
Professional Internet Engineer

Endpoint devices for Internet of Things (IoT) have limited computing resources and vulnerable against various attacks without external communication nodes. In this talk, we will explore how to connect simple IoT devices, such as Arduino UNO R3 based on 8bit AVR microcontrollers, to a communication node running Erlang/OTP, and build a fault-tolerant sensor node.

Talk objectives:

The issues covered in the talk will include the following details and other broader issues on the design trade-offs and security:

Communication protocol consideration between Erlang VM and IoT endpoint devices

Design principles of IoT endpoint devices for fault-tolerant systems with Erlang/OTP

Overcoming hardware limitation of IoT endpoint devices by Erlang/OTP

Target audience:

Programmers interested in connecting hardware devices to Erlang/OTP nodes, IoT application engineers intending to use Erlang/OTP, and system designers who want to give more fault-tolerance to the endpoint sensor devices.

Kenji Rikitake has been writing Erlang code since 2008. His recent open source work includes XORshift+/* code contribution to Erlang/OTP rand module, Erlang random number libraries of SFMT and TinyMT algorithms, and a hardware random number generator based on Arduino UNO R3. Kenji writes code since 1974. He has become an independent professional engineer since 2014, after working for various computer industry and academic/research organizations since 1990, including Digital Equipment Corporation, Kyoto University and Basho Technologies.

GitHub: jj1bdx

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Pakistan v Zimbabwe, Under-19 World Cup, Super League Quarter-Final February 11, 2006

Pakistan U-19s too efficient for Zimbabwe

Cricinfo staff

Pakistan 185 for 5 (Mohammad Ibrahim 39) beat Zimbabwe 181 (Samunderu 46, Khan 3-25) by five wickets

Pakistan chose efficiency over style on Saturday as they booked their place in the semi-finals with a straightforward win over Zimbabwe.

Pakistan's bowlers, so impressive in Friday's defeat of New Zealand, impressed again to dismiss Zimbabwe for just 181, before knocking off the total in 48 overs. Anwer Ali Khan, whose 5 for 34 wrecked New Zealand, took 3 for 25 while his opening partner Jamshaid Ahmed captured 2 for 42 and Riaz Khail picked up 4 for 29.

Zimbabwe's innings fell into several distinct phases. First there was an early struggle as they limped to 31 for 3 in the face of an onslaught from Anwer Ali Khan and Jamshaid Ahmed. Then Donald 'Kuda' Samunderu (46) and Keegan Meth (33) pulled things around with a fourth wicket stand of 65 before another cluster of wickets fell and Zimbabwe slipped to 136 for 8.

That collapse forced Sean Williams' side to draft in their Supersub, Friday Kasteni, in place of opening bowler Ian Nicolson. Kasteni's contribution in getting his side to a reasonably useful score was vital. Batting at number nine, he made 22 crucial runs and, together with Ronald Benade (18) the pair added 39, the second highest stand of the innings. Samunderu, Meth and Kasteni were the only players to reach 20 for Zimbabwe but 23 extras, including 14 wides, boosted their total which, inevitably, was no match for Pakistan.

Ibrahim Mohammed (39) and Rameez Raja (39) both made solid top-order contributions to set Pakistan on their way before Riaz Kail (26 not out) and captain Safaraz Ahmed (22 not out) finished the match off with an unbroken partnership of 36.

"I did not think there was much between the teams but I was definitely impressed by Pakistan's fast bowling," Zimbabwe's captain, Sean Williams, said. "We kept them out there chasing the target for 48 overs but we just did not get enough runs and our top order has failed in every game."

Although Pakistan took their time in their run-chase, they were wary of a replicating the collapse they suffered against Bangladesh earlier in the tournament.

"We did not want to make the same mistake we did against Bangladesh (when Pakistan collapsed) so we were happy to take as long as we had to in order to score the runs," said Pakistan coach Mansoor Rana.

Mansoor, whose team now face a rampant Australia in the semi-finals, was relaxed about his team's fortunes. "As long as we are fully prepared then it does not matter who we play because they are all good teams and it is simply what happens on the day," he said. "One good innings or one good spell of bowling can win a match."


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Variable Annuity Marketers Switch to ETFs

Variable annuity marketers are moving to ETFs after getting by burned active mutual fund managers.

In the WSJ story Laggards Get the Boot, Journal reporters Leslie Scism and Diasy Maxey write that insurance companies that offer variable annuities are making the switch after experiencing hedging issues with underperforming actively managed mutual funds.

The poor tracking of the funds caused the insurance companies to take billions of dollars in charges and moved them to switch to ETFs because they are easier to hedge and also less expensive.

Dutch insurer Aegon NV is now offering asset allocation portfolios built with Vanguard ETFs while MetLife is using State Street ETFs.

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The Europacolon Team

Dora Constantinides

Dora worked as part-time lecturer on Marketing, PR and Management Studies and was involved for a decade with The Cyprus Consumers' Association and the publishing of the first Good Food Guide of Cyprus.
At the age of 42 and with 3 children (11, 15 and 18) Dora was diagnosed with Dukes B Stage II (colorectal ca).

She underwent major surgery, had a colostomy and soon after was elected municipal councilor for Nicosia, representing the newly formed Green Party, for 21/2 years. In April 1997 she joined PASYKAF (The Cyprus Association of Cancer Patients and Friends) on the Administrative Team. Together with her personal experience her work added to the spark for raising awareness on colorectal cancer issues involving all the parameters from prevention and early diagnosis to treatment and preserving patients their quality of life at all stages.

Today, Head of Awareness at PASYKAF and contact person for EuropaColon she is committed to the campaign for reducing the incidence and mortality rates due to particularly colorectal cancer.”

Back to the EuropaColon Team
Registration No: 5314195 Registered Office: 92 Palatine Road, London N16 8ST.


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• The meetings are part of Parliament’s work to fight climate change
  • Governor Brown is this year’s COP23 Special Advisor for States and Regions
  • Debates come ahead of MEPs joining the COP23 in Bonn next Tuesday
Mr Tajani and Mr Brown during the debate on climate cooperation © European Parliament

Political groups discussed the way forward on climate cooperation with the Governor of California, who earlier also met with Environment and EU-US delegation MEPs, on Wednesday.

“It is of great importance to have this debate today with the leader of a US state, California, which we consider to be a very important regional state in the US and a key player in US politics”, said European Parliament President Antonio Tajani (EPP, IT) opening the debate with the Governor of California Edmund G. Brown.

“The risk of rising temperature in irreversible ways, with great destruction exacerbating inequality, poverty and migration, is going to happen soon. I am here going to COP23 to join other states and provinces throughout the world to push a climate action agenda and to get the job done”, said Mr Brown.

Video summary of this debate

Meeting with the Environment Committee and EU-US delegation

"Although the US decided to withdraw from the Paris agreement, an impressive number of US states and cities decided to uphold their share in the fight against climate change” said Environment Committee Chair Adina Ioana Vălean (EPP, RO), who will lead a delegation of MEPs to Bonn to attend the COP23 climate conference from Tuesday. “We are all aware that state-level action alone is not enough. We need to bring together governments on all levels, businesses, academia and civil society in a joint and coordinated effort to meet the ambition we set out in Paris two years ago”, she said.

EU-US Delegation Chair Christian Ehler (EPP, DE) said: “The UN Climate Change Conference started yesterday with strong, unified calls to hold to the path of the Paris Climate Change Agreement”. “This takes place against the backdrop of this year’s destructive hurricanes, fires, floods, droughts, melting ice and impacts on agriculture, which threaten food security”. “For us, it has become more and more important to engage with US States and their top political representatives, given the particular make-up of the US political system, alongside our regular contacts from Congress and the administration”, he added.

Governor Brown said: “The nature of the threat from climate change is existential, and the level of commitment is not up to the threat”. “Decarbonizing requires a transformation of our whole civilization, fossil fuels are the basis on which we function today. We are fossil fuel people, carbon people!”. “Even the 2°C goal may not be enough” he added.

Quick Facts

Governor Edmund G. Brown was named Special Advisor for States and Regions ahead of this year’s COP23 by Fijian Prime Minister Frank Bainimarama – president of COP23 – at a ceremony where Fiji became the latest government to join the Under2 Coalition.

The coalition includes 176 jurisdictions on six continents, collectively representing more than 36 countries, 1.2 billion people and $28.8 trillion GDP- equivalent to over 16 percent of the global population and over 39 percent of the global economy.

Governor Brown created the US Climate Alliance, together with Gov. Jay Inslee (Washington) and Andrew Cuomo (New York), in response to the U.S. federal government's decision to withdraw the United States from the Paris Agreement. It currently numbers 15 states, comprising 36% of the US population and USD 7 trillion in GDP.


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Upcoming events – Nightstar's gene therapy and Alnylam's givosiran await key readouts

Nightstar hopes that early gene therapy data will give it a spark, while Alnylam awaits pivotal results for one of its biggest pipeline prospects, givosiran.

Welcome to your weekly digest of approaching regulatory and clinical readouts. Although gene therapy approaches are still in their infancy, the potential of a "once and done" treatment means that all updates in the field are watched with interest. The UK group Nightstar will soon come under the spotlight with preliminary phase I/II results for NSR-RPGR, its X-linked retinitis pigmentosa candidate, due at the Euretina 2018 conference on September 22.

The focus of the 15-patient Xirius trial of NSR-RPGR, which uses the AAV8 vector to transport optimised human retinitis pigmentosa GTPase regulator (RPGR) DNA into the patient's eye, will be safety.

But investors will also be looking for improvements in retinal sensitivity, the amount of light perceived in specific parts of the retina. And with an expansion study planned for the fourth quarter, any dose-escalation effects from the five different cohorts in the trial will also be examined closely.

X-linked retinitis pigmentosa is a rare inherited disorder that primarily affects boys and is characterised by mutations in the RPGR gene, which causes the loss of photoreceptors, the cells responsible for converting light into visual signals. XLRP sufferers typically experience increasing symptoms of night blindness, leading to a loss of peripheral vision and then full vision by the age of around 40.

Several other companies are developing gene therapies for retinitis pigmentosa, and there are also cell therapies in development, such as Reneuron's ReN003 (Deal hopes revive Reneuron, July 11, 2018). Still, Nightstar is ahead, with even the most advanced of its competitors not due to report data until next year.

Even if Xirius is a success, however, NSR-RPGR could still face obstacles. Spark's Luxturna, the first gene therapy for a rare eye disease, might have blazed a trail with its approval in retinal dystrophy, but the reimbursement landscape for novel gene therapies is still in its infancy, and payment terms remain uncertain.

Nightstar might need a more experienced partner to navigate these largely uncharted waters. If Xirius reads out positively it could give it more options here.

Selected therapies in clinical development for retinitis pigmentosa
Project Company Description Trial ID Data due
Phase II
jCell Jcyte Stem cell therapy NCT03073733 2019
Phase I/II
NSR-RPGR Nightstar Therapeutics RPGR gene therapy Xirius, NCT03116113 Feb 2019
ReN003 Reneuron Stem cell therapy NCT02464436 2019
RST-001 Allergan ChR2 gene therapy NCT02556736 2019
AAV-RPGR Meiragtx RPGR gene therapy NCT03252847 2020
HORA-PDE-6B Horama PDE6B gene therapy NCT03328130 2020
BIIB088 Biogen/Applied Genetic Technologies RPGR gene therapy NCT03314207
2021,      2022
Source: EvaluatePharma.

Alnylam is also targeting an ultra-rare disease, acute hepatic porphyrias, with its subcutaneously delivered RNA interference candidate givosiran, which could become its second marketed product after the recently approved Onpattro, the first RNAi therapy to be greenlit.

Givosiran's future hinges on results of the Envision trial, topline results of which will be available by the end of this month. The primary endpoint is the annualised rate of porphyria attacks over six months, but initial data will involve a biomarker, urinary aminolevulinic acid, which Alnylam hopes will be enough to support accelerated approval.

The company has talked up acute hepatic porphyrias as the equivalent of hereditary angioedema, which has defied early expectations to become a $1.6bn market. At present the only available treatment for acute hepatic porphyrias is hematin, which must be given via intravenous infusion.

Givosiran works by preventing the translation of the ALAS1 protein, which in turn lowers levels of delta-aminolevulinic acid (ALA) and porphobilinogen (PBG). Elevated levels of these two products causes acute neurovisceral attacks, characterised by severe pain, changes in heart rate or blood pressure, vomiting and sweating, which often put patients in hospital.

Analysts have so far been positive about givosiran, given that in previous trials the treatment has been able to reduce levels of urinary ALA by over 70%, earning it a breakthrough therapy designation. The only potential fly in the ointment for Alnylam might be the relatively small amount of safety data, but in clinical trials there have been no imbalances in serious adverse events.

If the Envision results are positive Alnylam plans to file givosiran by the end of the year, with approval expected in 2019, a year ahead of schedule. The project could bring in $446m in 2024, according to consensus sellside forecasts from EvaluatePharma. If Alnylam's hopes come true this could well rise.

Study Trial ID
Envision NCT03338816

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Monthly Archives: June 2013

A Stylish Heating Solution – Baseboard Heaters

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What is that special thing that makes baseboard radiator heat a good option to pursue? The baseboards of your home are fantastic place to install a heating system because of one simple principle – heat rises. Through the use of a baseboard radiator heat system your entire home will be able to be warm, from the floor on up. Baseboard hot water heating systems are working great because the “radiators” that bring warmth into the room are installed very low, along the baseboard. Then the water is heated in a boiler tank, either by gas, oil or electricity in a system that is similar to, but separate from the water heater that supplies your plumbing system. These systems are clean because they are closed, so you do not have to worry about dusty air being blown through vents all over your house, and they are extremely quiet because of the way they work.

baseboard heaters

Lets see how do they work exactly, and why it may be a good option for your home. We have already established that water is heated, and this is what provides the heat to your home; but once the water is heated what happens? Well in general this is how it works: most baseboard heater units have an electric motor that pumps the water through the house through a series of pipe systems. When you install your system you want to make sure that the first radiator of the house is installed in the main room, or the room you would want heated the best because hot water enters the radiator first, so that radiator is normally the hottest of any. The heat flows from the surface of that radiator, and some of that heat is transferred, and heats the room. Thus you get a nice toasty room, but the water that comes out of the exit end of that radiator is cooled somewhat.

baseboard heating

The water follows the series of pipes, flowing to the next radiator in the system where more heat is extracted from the water and released into the room. By nature of the system, the last room in the system receives the coolest water. Once it has run its course, the water goes back to the boiler where it is heated and re-circulated again. This is a closed system. All the water in the system remains in the system. The main water supply from the house is fed into the circulation system through a pressure regulator so that any lost water is replaced instantly.

baseboard radiator

This is a neat system for households where not everyone likes the same temperature. It is almost like having a different thermostat for each room of the house, but significantly less expensive. However, not all baseboard heaters have the problem of the water cooling significantly from the first radiator to the last. You can buy a system that has a flow control valve on each of the radiators which is adjusted so that a smaller amount of water flows through the first radiator, and so that the excess flow is diverted around and on to the next radiator in the system.

But the question is, if the room is heated through water, how can you control the heat that you want? Wouldn’t that mean you are at the mercy of how hot the water is? Normally the boiler temperature is controlled internally so that heat is available instantly when it is called for by the room thermostat. Basically, when you flip on your thermostat, a signal is sent to the circulation pump which turns on and begins circulating hot water through the house. You can set the temperature, when you want them to work and how long do you want them all. You got all the freedom, all the time.


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Monthly Archives: April 2013

Wedding Ring Metals - The FactsSince platinum, silver along with platinum include the best acknowledged materials used by wedding companies, in this information, we look at many of the newer mining harvests, palladium, titanium along with tungsten, what creates them particular and many of the benefits of getting a wedding band made from one of them metal varieties.

Palladium — Palladium has been online for years but as a consequence of difficulties using casting, they have only ended up used throughout jeweler for you to any wonderful extent. It is just a pure and yellow metal from your platinum family therefore has a lot of the same traits as platinum a highly desired metal nevertheless rare so because of this, expensive. Palladium is often a naturally bright metal which has a shiny conclude and its’ acceptance is progressively increasing throughout engagement and wedding band designs.

Titanium — Titanium is often a natural material abundantly intended for mining, but although it is not platinum, the jeweler made out of this material is perhaps not widespread. Titanium has been used in several industries since early 1950′ for the properties, chiefly their resistance for you to corrosion as well as strength for you to weight rate. It is often a lustrous material and will not require just about any special coating to generate it solid or preserve it via getting scratched mainly because it is effortlessly so, contrary to white platinum.

Tungsten — Tungsten as well as tungsten carbide as it is far better known will be the hardest metal employed in wedding companies. Some perhaps claim it to get an ‘indestructible’ material as their reputation pertaining to durability is an awesome experience. It can be virtually damage proof all of which will retain their shine once and for all. Tungsten marriage ceremony rings appear in many patterns, can be combined with other precious metals, can always be layered as well as engraved pertaining to amazing designs which enable it to be inlaid using diamonds, wood and also other materials.

While using growing development for more sophisticated wedding rings, the modern range mining harvests are effectively in give preference to. They are incredibly different through the traditional music band and get both a whole new age appearance and feel about these people. With lots of original designs available, these mining harvests have various other features that leave them particular. They are incredibly hard mining harvests making wedding rings made suitable for everyday don, and titanium along with palladium are generally incredibly light and portable materials.

Elegance and Style that Won't Blow Your BudgetIf you intend your wedding ceremony then you may be all way too aware that among the many expenses is the price tag on your dream wedding dress. Fortunately, with the great selection of good quality discount bridal dresses available nowadays, it’s possible to take a look like a new princess with no spending a large amount of. Savvy brides-to-be are aware that online to assess prices and methods of bridal dresses can bring about a true bargain. Consequently, get online and pay attention to how much you’ll be able to save!

The World Wide Web is also a terrific place to acquire up-to-date using what’s hot for the fashion the front. Simple your wedding gown in girly styles, recalling your grace in the late 1940s years, is currently very well liked. A biggest selling wedding costume material to get on the check for is Genoa textile, which is often a heavyweight fabric which has a soft system. It hangs elegantly and is also wonderful for you to wear, mainly because it doesn’t cling for a body. Latest bridal costume trends propose brides are generally turning in direction of halter necks, spaghetti band and heart-shaped necklines as being a graceful replacement for strapless clothes. Floor-length bridesmaid gowns presenting intricate textures along with subtle decorations are increasingly popular among popular brides.

Designer bridal dresses decorated using delicate beadwork details, chiffon styles and wide lace top accents give a sophisticated along with feminine search. If you’re fitting in with small wedding finances, these lovely designs are certainly not necessarily through your price selection. By doing all of your homework one can find a good looking discount bridal gown at an easily affordable price. The truth is you may dress your entire bridal bash in much less expensive attire.

You’ll find loads involving stunning nevertheless cheap outfits available. Involve your very best self friends and have hunting online for a lot of fantastic offers! With watchful planning that will unique bridal gown you’ve always thought of can always be yours at the reasonable price tag, leaving you a higher price to dedicate to making your “special ” day select a beat!

Royal Wedding - Wedding Guests And Party Make Their Way To Westminster AbbeyDoes anyone sometimes speculate why men and women do selected things? Like why the trouble of getting an expensive bridal gown that feels is to be used for starter’s day? Why not simply find a great dress that one could wear in regular occasions following actual wedding ceremony instead involving spending a lot on a married relationship dress? Effectively, some cultures are here to be. Instead involving spending a long time and electricity pondering these people, the best you’re able to do is recognize them along with adapt them available for you. Take by way of example tradition of your wedding gown. All around the globe, wedding attire worn by simply brides on the wedding day can be a revered convention. In simple fact, half your congregation seems to be forward on the wedding dress above all else.

If you’re planning your marriage ceremony and seeking information about the best way to spice your bridal gown, you want to do your preparation. You should understand your journey that your wedding gown has traveled after a while. This means, you are going to be better placed to generate a good decision in relation to choosing your wedding costume.

Have anyone been sampling your wedding gown that are certainly not white throughout color even though wondering whether you happen to be on target? Well, you happen to be. There isn’t law against your wedding gown that are generally, say, violet, red as well as true dark-colored in coloring. In simple fact, centuries previously, the bridesmaid gowns which are made throughout these hues were a new preserve in the wealthy. Wealthy birds-to-be wore clothes of coloring adorned using jewels in ways that they truly glittered inside sunshine of a summer wedding ceremony. Fast onward to right now, and you can afford to take a look good on the wedding morning without rooting a hole as part of your pocket.

Following color your wedding gown followed your white wedding dress. Unfortunately, white would not seem a functional shade for the majority of purposes. This specific saw the idea quickly ditched pertaining to other preferred, namely green and orange. In your 1800s, gray be a favorite amid brides via poorer people. This happens because they may wear wedding dresses following wedding morning. All your dresses essential were a number of adjustments coming from a tailor and they also were fine.

A wedding ceremony is an event that occurs mostly only once in your life. This is the reason why such ceremony is considered one of the most special events in your life. Even if it occurs twice or three times in your life, probably because you have had a divorce or two or because your spouse passes away, this ceremony is still considered special. Because it is special, you have to struggle hard to keep it unforgettable. One strategic way to do that is by hiring a professional wedding videographer to record that special event. Although you can always do the video recording by yourself, hiring a professional to handle that job is more advisable because a professional videographer can decide which parts of your wedding ceremony are worth remembering and emphasizing. San Francisco Wedding Videographer is always available to hire if you carry out your special event in that city.

Wedding VideographerYou may ask about why you should hire a videographer. Is a professional photographer who is present at your event venue not enough? Well, of course you can always hire a photographer to capture the most important parts of your wedding ceremony. However, a photographer can only produce still images and if he/she fails to capture a specific special moment during the event, there is no way he/she can recapture that moment. A videographer will record all special moments taking place in your wedding ceremony without missing any of them. Therefore, you will never be disappointed by the job that he/she carries out. It is also possible for you to hire both a photographer and a videographer during your wedding ceremony if you believe that the services provided by both of them are similarly necessary.

Hiring a videographer in San Francisco is relatively easy. Just visit his/her website to scrutinize his/her portfolio and credentials and you can find out whether or not he/she is reputable enough. Hire him/her right away if you think that his/her service will be helpful for you.

Preserve Your Wedding DressesWedding!! Normally the one day in a very girl’s lifestyle that she is going to never forget about. But the idea so comes about that the girl forgets with regards to her bridal gown after wedding is around. A bridal gown is an issue that is used by a morning and remains with a hanger the remaining of their life. Many young ladies buy bridal dresses years before a married relationship, and whether it is not stored properly you’ll find chances of computer getting spoiled prior to wedding. Preserving a married relationship dress is important, regardless of unique before wedding or immediately after.

A several months before wedding you step out to the market industry or look online pertaining to cheap bridal dresses. After visiting many stores and under-going many wedding gowns you end up picking one. As soon as you make the choice and get a dress, occurs the coping with part. Handling the gown very carefully is important. When you acquire the costume, the shop may offer you a complimentary clothe bag. Or else, you can get it coming from a supermarket. A clothe bag helps keep the bridesmaid dresses safe and sound from just about any damage, therefore, itought to.

After you do have a garment bag for ones beautiful bridesmaid dress, anyone can hang the gown inside your bag. As your current bridal wear is going to be long, it is significant to preserve it a place high enough in order that the skirt won’t touch the bottom. The position you hang it ought to be a shut down space as being a closet. Before anyone hang your bag make certain that the position isn’t rainy or stinky?

Due on the excitement, you may be trying for the dress many times ahead of actually donning it to the wedding. You need to understand that bridal dresses are incredibly delicate items plus the more anyone take them don and doff, there is often a greater risk that this beading may possibly become loose or maybe fall involving. So make sure you avoid taking wedding dress out of your bag for years in order to stop it via getting harmed or creased.

Following wedding, you may want to clean the gown to preserve it in a very good issue. For this it can be advised for you to approach an experienced dry cleaner dedicated dry cleaning bridal dresses. If just about any damaged features occurred on the dress, you’ll be able to immediately understand it fixed. As soon as you are carried out with the cleanup and mending damages in the dress, hang it last the cloth bag along with store it inside wardrobe.


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Thursday, March 14, 2013

Veggie Pizza

I love veggie pizza as it combines all of my favorite things: cheese, ranch dressing, crescent rolls, and veggies!

I lived off of this after Monkey was born and made it a few weeks ago so I’d have something for lunch at work. However I ate half of it before I even made it to a work day. This is half of a regular recipe and can easily be doubled if you are making it for more than 2 (or in my house, more than just me).

Please forgive me, this photo is ridiculously bad.

Veggie Pizza

Crescent roll dough
1 package of cream cheese
½  cup sour cream or mayonnaise (really doesn’t matter)
½ packet of ranch dressing mix
½ - 1 cup shredded carrots
½ - 1 cup red cabbage
½ - 1 cup broccoli
½ - 1 cup cauliflower
½ - 1 cup frozen peas
Shredded cheddar cheese

Bake the crescent dough at 350 degrees for 12 minutes.  Remove from the oven and let cool.

Mix the cream cheese, sour cream/mayonnaise, and ranch dressing. Spread on cooled crust.

Chop and/or shred veggies and layer on the pizza.

Chill in the fridge and serve.

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Hannah S Cocktail Dress 27877

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Youthful and Flawless Lace and Satin Sweetheart Neckline Peplum Cocktail Dress by Hannah S Style 27877!

Life is a never-ending party with Hannah S Style 27877. This figure-hugging cocktail dress has a strapless sweetheart neckline, glittering rhinestone beading over lace with satin and a trendy peplum mini skirt that is ready to party all night. This Hannah S dress is perfect for relaxing after prom, recognizing your achievements on your graduation, dancing the night away at homecoming, helping capture the crown at your next pageant, attending a party, making an appearance at a reception, making any special occasion remarkable, turning sweet sixteen, witnessing the union of your son or daughter on their wedding day, celebrating a friend's wedding, or any once in a lifetime event you may be attending.

FREE SHIPPING!* Usually ships within 3-5 business days. We ship worldwide. We offer Low Price Guarantee. We don't collect sales tax outside the state of Illinois. We are an Authentic Authorized Retailer.

This dress MAY be returned. Please refer to our return policy.

Fabric: Lace and Satin

Available Colors: Pink, Aqua

Available Sizes: 0, 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30

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Manufacturer: House of Wu

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Hannah S Sale Cocktail Dress 27769

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Graceful and Posh Jersey Sweetheart Neckline Fitted Sheath Dress by Hannah S Style 27769!

Exude a certain glamorous charm when you wear Hannah S 27769. This jersey pageant dress features a sweetheart neckline with a sparkling rhinestone accent, a strapless bodice and a sensual short sheath for a slim silhouette in shirred tulle. This Hannah S dress is perfect for relaxing after prom, dancing the night away at homecoming, helping capture the crown at your next pageant, attending a party, or any once in a lifetime event you may be attending.

FREE SHIPPING!* Usually ships within 3-5 business days. We ship worldwide. We offer Low Price Guarantee. We don't collect sales tax outside the state of Illinois. We are an Authentic Authorized Retailer.

This dress may NOT be returned. All Sales Final. Please refer to our return policy.

Fabric: Jersey

Available Colors: Purple, Yellow

Available Sizes: 0, 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30

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Manufacturer: House of Wu

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Vice Mayor Garcia Wants to Enhance the City’s Use of Technology Through Creation of New Commission

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Vice Mayor Robert Garcia - Photo from Facebook

Vice Mayor Robert Garcia – Photo from Facebook

Long Beach Vice Mayor Robert Garcia has proposed the creation of a Technology and Innovation Commission to advise the Council on new technology, investing in technological innovation and infrastructure, and to serve as a clearinghouse for ideas to enhance the City’s use of technology and its place in the tech economy.

“Long Beach can be a national leader on technology, the new tech economy, and civic innovation,” said Vice Mayor Garcia. “Over the last few years we have made significant investments in technology infrastructure, but there is much more we can do.”

If the legislation were approved by Council at its Meeting of September 17, the commission proposal would head to the Economic Development & Finance Committee of the City Council, and then back to City Council for final approval. The Commission would be comprised of Long Beach residents with special skills, knowledge, expertise and interest in technological innovation.

Over the last few years, Vice Mayor Garcia has authored numerous pieces of tech legislation and initiatives including the creation of the “Go Long Beach” smartphone application, new online permits and licenses, the use of social media for city departments, an open government initiative, an online city contract database, a new city website launching next year, free WiFi initiatives for parks and libraries, and technology upgrades throughout the city. In addition, he requested a new $250,000 technology and innovation fund in the FY 2014 City Budget that was approved by the City Council.

“We want our best and brightest minds to serve on the commission, and to help us find new ways to solve our civic challenges,” said Garcia.

The Commission would be made up of 11 members, 1 from each district, and 2 at-large members for a total of 11. All appointments are made by the Mayor and approved by the City Council.

The legislation is cosponsored by Councilmembers DeLong, O’Donnell, and Neal.

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Storage Sales Slump In 2001

Demand for data storage will shrink this year but will rebound quite nicely over the next three, according to a new report by market research firm IDC.

Demand for data storage is forecast to shrink this year but will rebound over the next three, according to a new report released Tuesday by market research firm International Data Corp.

But dont expect the form of storage devices to look the same in 2004 as they do now, the report indicates.

The worldwide market for disk storage hardware, software, and services shrank about 6 percent this year to $57 billion, but will grow to $70.6 billion in 2004, the IDC report said.

The tape storage and disk drive segments were not included in the report. However, IDC analyst Charlotte Rancourt said that if those were included the total worldwide storage market "could well be a $100 billion market" by 2005.

"IDC is not forecasting a steep hockey stick kind of thing... Its going to take the next three years to get the market in a position comparable to where it was in 1999," said Rancourt, in Framingham, Mass.

One wildcard clouding the forecasts is the proposed merger of Hewlett-Packard Co. and Compaq Computer Corp., Rancourt added.

Hard hit was the high-end external DAS (direct-attached storage) segment, which this year will post sales of $17.8 billion. Along with internal DAS this account for about two-thirds of all storage revenues. That compared with external DAS storage sales of $25.5 billion last year.

IDC forecast the market for direct-attached storage to grow to $29.6 billion in 2005, but that number also includes internal DAS. But by then, DAS will only account for 34.3 percent of the total storage technology pie.

Taking over some of that market share will be network-attached storage, also known as NAS. In 2001, NAS will account for a 7.5 percent slice of the storage market but will grow into a $5.6 billion, 19 percent slice, in 2005. Storage-area networks, or SANs, will swell from a 25.8 percent share of the market this year to a 46.7 percent share in 2005.

Most of the same companies are in all three spaces, the report noted.

Overall, Compaq in 2001 has the biggest combined internal and external disk systems revenue share with 18.2 percent of the worldwide market, on $4.4 billion in sales. The Houston-based company narrowly regaining the lead it lost to EMC Corp. in 2000.

EMC, of Hopkinton, Mass., has a 15.6 percent, $3.77 billion stake in the market in 2001, the report states. IBM is third at 14.2 percent, followed by HP (8.1), Sun Microsystems Inc. (6.5), Hitachi Ltd. (4.2), Dell Computer Corp. (4.0), Fujitsu (3.5), Hitachi Data Systems (3.0), NEC (2.2), NCR Corp. (1.6), and Fujitsu-Siemens (1.0).

The industrys top-tier players, like EMC, IBM, Compaq, HP, Sun, and Network Appliance Inc. are all in the top few spots in various subcategories. EMC saw its leading market share of the $17.7 billion external storage category fall more than 4 points to 21.2 percent in 2001 compared with 2000. Second-place Compaq jumped from 14.7 to 15.4 percent, IBM jumped from 7.8 to 12.2 percent, and the combined Hitachi Ltd. and its Hitachi Data Systems division jumped from 6.7 to 11.1 percent.

EMC also leads in NAS; its 2001 share of 42.3 percent accounted for $777 million of this years $1.84 billion market. That was up from 32.5 percent at $526 million last year. EMC swaps places with Network Appliances current 32.5 percent, $598 million share, which led with 45.4 percent and $735 million last year.

The SAN story is similar: EMC leads with a decreasing 37.9 percent, $2.37 billion share of the $6.25 billion market. IBMs share of the SAN market in 2001 is 18.2 percent, and Compaqs is 17.9 percent.

For end users to make sense of each companys current and expected claim-making, its important to consider individual needs, Rancourt said.

"What theyve done is taken subsets and slices of the market... and depending on how one puts value in [their] vantage point, then this is more important than that," she said.


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Newborn Baby With Umbilical Cord Dumped In A Refuse Site In Delta - Very Graphic

Chineke ekwekwala ihe ojoo. Right now am going to doubt the part of the bible that says God gives children simply because God is not a cruel God. He can't be giving children and letting them been dumped in a refuse dump like this.

Yesterday, their was another incident of someone throwing his baby into gutters I think in Delta State too and you can't still stand their and tell me God gives children. He is not and will never be a cruel God. You only get pregnant when you have unprotected s*x. QED

This is really unfortunate. The new born baby was found in a refuse dump this morning kept by a wicked supposed mother with placental and umbilical cords all intact. The baby reportedly died before rescue came. This happened few minutes ago at Iwehrekpokpo Road in Ughelli North, Delta state.

More pics below...

Newborn Baby With Umbilical Cord Dumped In A Refuse Site In Delta - Very Graphic Newborn Baby With Umbilical Cord Dumped In A Refuse Site In Delta - Very Graphic Reviewed by Exlink Lodge on Wednesday, May 17, 2017 Rating: 5

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FDA Confirms a 510(k) De Novo Path for EyeGate’s Device, the Ocular Bandage Gel, Following Pre-Submission Meeting

Top-Line Data from First-in-Human Pilot Study Expected by Year-End 2016

WALTHAM, Mass., November 17, 2016 — EyeGate Pharmaceuticals, Inc. (NASDAQ: EYEG) (“EyeGate” or the “Company”), a clinical-stage specialty pharmaceutical company that focuses on developing and commercializing products for treating diseases and disorders of the eye, today announced that, following a pre-submission meeting with the U.S. Food & Drug Administration (“FDA”), it plans to pursue U.S. regulatory clearance of its EyeGate Ocular Bandage Gel (“EyeGate OBG”), via the De Novo 510(k) pathway. EyeGate OBG is the lead product candidate from the Company’s cross-linked, thiolated carboxymethyl hyaluronic acid (CMHA-S) platform. The Company plans to release top-line results by year-end, from its initial pilot study evaluating the ability of EyeGate OBG to accelerate ocular surface re-epithelialization following photorefractive keratectomy (“PRK”).

“We are extremely encouraged by our dialogue thus far with the FDA around EyeGate OBG, and are pleased to have a clear clinical and regulatory path forward for our first-in-kind eye drop that could accelerate recovery from post corneal surgery and injury”, said Stephen From, President and Chief Executive Officer of EyeGate. “We believe that the De Novo process, which is for medical devices without predicates, provides evidence of the novelty of our EyeGate OBG product. We look forward to announcing the top-line data from our PRK pilot study by the end of the year.”

The EyeGate OBG is a synthetic biocompatible CMHA-S hydrogel, capable of coating the ocular surface and designed to resist degradation under conditions present in the eye. This prolongs residence time of the bandage on the ocular surface, addressing the limitations of current non-cross-linked hyaluronic acid formulations. Additionally, cross-linking allows the product’s viscosity to be modified to meet optimum ocular needs. The EyeGate OBG is a sterile liquigel that is designed to be administered to the eye from a single-use vial four times per day for a maximum of 28 days.

About EyeGate

EyeGate is a clinical-stage specialty pharmaceutical company that is focused on developing and commercializing therapeutics and drug delivery systems for treating diseases of the eye. EGP-437, the Company’s first and only product in clinical trials, incorporates a reformulated topically active corticosteroid, Dexamethasone Phosphate that is delivered into the ocular tissues through EyeGate’s proprietary innovative drug delivery system, the EyeGate® II Delivery System. In addition, EyeGate is developing, through its wholly-owned Jade subsidiary, products using cross-linked thiolated carboxymethyl hyaluronic acid (“CMHA-S”), a modified form of the natural polymer hyaluronic acid (HA), which possesses unique physical and chemical properties such as viscoelasticity and water retention. The ability of CMHA-S to adhere longer to the ocular surface, resist degradation and protect the ocular surface makes it well-suited for treating various ocular surface injuries. For more information, please visit www.EyeGatePharma.com.

Safe Harbor Statement

Some of the statements in this press release are “forward-looking” and are made pursuant to the safe harbor provision of the Private Securities Litigation Reform Act of 1995. These “forward-looking” statements include statements relating to, among other things, the commercialization efforts and other regulatory or marketing approval efforts pertaining to EyeGate’s products, including EyeGate OBG, EyeGate’s EGP-437 combination product, and those of Jade Therapeutics, Inc., a wholly owned subsidiary of EyeGate, as well as the success thereof, with such approvals or success may not be obtained or achieved on a timely basis or at all. These statements involve risks and uncertainties that may cause results to differ materially from the statements set forth in this press release, including, among other things, certain risk factors described under the heading “Risk Factors” contained in EyeGate’s Annual Report on Form 10-K filed with the SEC on March 30, 2016, EyeGate’s Quarterly Report on Form 10-Q filed with the SEC on May 13, 2016 or described in EyeGate’s other public filings. EyeGate’s results may also be affected by factors of which EyeGate is not currently aware. The forward-looking statements in this press release speak only as of the date of this press release. EyeGate expressly disclaims any obligation or undertaking to release publicly any updates or revisions to such statements to reflect any change in its expectations with regard thereto or any changes in the events, conditions or circumstances on which any such statement is based.

Lee Roth / Joseph Green
The Ruth Group for EyeGate Pharmaceuticals
646-536-7012 / 7013
lroth@theruthgroup.com / jgreen@theruthgroup.com