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December 2, 2016
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MilliporeSigma Launches Parteck® MXP Excipient for Increased Solubility
  • Enhances solubility of active pharmaceutical ingredients with poor bioavailability
  • Enables higher amount of API loading with excellent stability

Billerica, Massachusetts, December 2, 2016 MilliporeSigma, a leading science and technology company, today introduced Parteck® MXP, a  polyvinyl alcohol-based excipient that enhances solubility of a wide range of active pharmaceutical ingredients (APIs) with poor bioavailability.

Parteck® MXP excipient maintains stability at temperatures above 200 degrees Celsius, making it well-suited for hot melt extrusion (HME), a process used by drug manufacturers to enhance the solubility and bioavailability of APIs. The new excipient can achieve drug loads of 30 percent or more, while other excipients may be limited to 10-15 percent in HME. Drug load is a measure of the amount of API by weight that can be combined with the excipient.

“More than 90 percent of drugs in the pharmaceutical pipeline have solubility issues that lead to poor bioavailability, a key factor in the success of a drug candidate,” said Andrew Bulpin, Head of Process Solutions Strategic Marketing & Innovation, MilliporeSigma. “Parteck® MXP excipient is the latest addition to our comprehensive excipients portfolio and allows our customers to address solubility challenges that otherwise might have prevented promising and potentially life-changing drug candidates from progressing through the pipeline.”

The new excipient has been successfully tested on eight commonly used and poorly soluble APIs, including ibuprofen, indomethacin and itraconazole, and can be used in formulations for both immediate and sustained release.

In contrast with more complex excipients, Parteck® MXP excipient uses simple chemistry, potentially streamlining regulatory processes. The polymer used in Parteck® MXP is generally recognized as safe (GRAS)i by the U.S. Food and Drug Administration and complies with U.S. Pharmacopeia, European Pharmacopeia and Japanese Pharmacopeia for excipient monographs.

Parteck® MXP excipient is an expansion of MilliporeSigma’s portfolio of products that enhance bioavailability by improving poor aqueous solubility and controlled release. After rigorous testing, Parteck® MXP excipient will also be incorporated into the company’s Emprove® program. Using this program, customers have instant, online access to regulatory and technical information about the excipient, more than 400 other chemicals, filters and single-use components to facilitate risk assessment and qualification processes.

i http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/NoticeInventory/ucm153970.htm

About the Life Science Business of Merck KGaA, Darmstadt, Germany
The life science business of Merck KGaA, Darmstadt, Germany, which operates as MilliporeSigma in the U.S. and Canada, has 19,000 employees and 65 manufacturing sites worldwide, with a portfolio of more than 300,000 products enabling scientific discovery. Udit Batra is the global chief executive officer of MilliporeSigma.

Merck KGaA, Darmstadt, Germany completed its $17 billion acquisition of Sigma-Aldrich in November 2015, creating a leader in the $125 billion global life science industry.

Merck KGaA of Darmstadt, Germany is a leading company for innovative and top-quality high-tech products in healthcare, life science and performance materials. The company has six businesses – Biopharmaceuticals, Consumer Health, Allergopharma, Biosimilars, Life Science and Performance Materials – and generated sales of €12.85 billion in 2015. Around 50,000 employees work in 66 countries to improve the quality of life for patients, to foster the success of customers and to help meet global challenges.

Merck KGaA, Darmstadt, Germany is the world’s oldest pharmaceutical and chemical company – since 1668, the company has stood for innovation, business success and responsible entrepreneurship. Holding an approximately 70 percent interest, the founding family remains the majority owner of the company to this day. The company holds the global rights to the name and the trademark “Merck” internationally except for the United States and Canada, where the company operates as EMD Serono, MilliporeSigma and EMD Performance Materials.


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Electromagnetic Field Simulation Made Easy

Electromagnetic Field Simulation Made Easy by EMWorks by providing finite element software to calculate electromagnetic field, magnetic field, electric field, magnetic flux, and electrical flux. The field and flux could be caused by an electromagnet, a magnet, a coil, a high speed digital circuit, an antenna, or RF and Microwave components.  The company's flagship products are EMSHFWorksSimClaim, and ATLASS.  EMS addresses static magnetic and electric field calculation, electromagnetic induction, eddy current, skin effect, proximity effect, motion and motion industries issues.  In addition to electromagnetic field and flux, it calculates magnetic force and torque, electric force and torque, electromagnetic force and torque, impedance, inductance, resistance, capacitance, back emf, ohmic loss, eddy loss, core loss, heat loss, copper loss, and electromagnetic energy.  HFWorks targets electromagnetic radiation, electromagnetic waves, electromagnetic interference, electromagnetic compatibility phenomena for frequencies higher than RF.  In addition to near and far electromagnetic fields and waves, it computes scattering parameters, antenna pattern, antenna gain, antenna directivity, impedance, and losses.  SimClaim has the capabilities of EMS and HFWorks combined.  In addition, it has standalone static structural and thermal solvers.  ATLASS is a calculator for quick Electronic Design Automation, ICs, RF ICs, PCBs, and digital circuits design needs. Furthermore, EMWorks provides integrated Thermal, Structural, and Motion solvers in a hassle-free true Multiphysics simulation platform.

A plugin to Solidworks, Autodesk Inventor, and SpaceClaim

Electromagnetic software packages significantly facilitate your, the designer's, task without the need to build physical prototypes, hence you could reduce the time to market your products and services. Unfortunately, most of the commercial magnetic, electrical, electric force, magnetic force, magnet, and electromagnetic software packages that you may utilize for this end are cumbersome and difficult to use. In addition, they oftentimes require from you to simplify the geometry, which can result in the loss of critical details and thus affecting the performance of your end products. EMWorks' products make the exception. They are fully and seamlessly embedded in the three main CAD platforms: Solidworks, Autodesk Inventor, and SpaceClaim. Consequently, you don't need to "reinvent the wheel" and just grab a CAD model from the drafting department and start simulating instantly.  For example, you can obtain the electric force, electrostatic force, or magnetic force in a RF MEMS switch or a permanent magnet motor assembly in less than ten minutes.

Grabcad, 3dcontencentral, traceparts

In recent years a burgeoning number of free 3D CAD models -millions- have become available in CAD depositories such as grabcad.com,   www.3dcontentcentral.com, and  www.traceparts.com.  Consequently, you can simply grab a CAD model from the depositories, make necessary changes, and start your finite element analysis instantly.

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There can be no leadership without influence, because influencing, including through the power of example, is the way leaders lead. There is a profound difference between leadership and management. Both are important within an organization, but management is a process and can only be implemented on the basis of skills, while leadership has more of self-knowledge, self-management, self-development.

Sam Walton, the entrepreneur who created Walmart, said that “outstanding leaders go out of their way to boost the self-esteem of their personnel. If people believe in themselves, it’s amazing what they can accomplish”. It’s one of the positive effects that leaders generate in the company with the influence they have on teammates.

Often the “manager or leader” dilemma?

Both the managers and the leaders want to achieve the goals of the organization. Managers do it by planning, organizing, structuring processes, assigning tasks, monitoring and measuring outcomes. But managers also use influence because only part of managerial work cannot be achieved only through control and use of authority. When managers have to create the environment in which people are motivated, involved in self-development and want their performance, they can not do it only through command and control methods.

What are people waiting for?

People respond best when involved in consultation and/or decision processes, they work best when they are listening to the process improvement proposals. Team people remain loyal and involved when they feel respected, confident, well-informed and work in an environment where they feel they are continually developing. That’s why exceptional leaders and managers are turning to coaching/mentoring tools and open up emotionally. They constantly work with themselves to provide the best example to all of their colleagues in the company.

How do leaders lead?

Leaders lead by mobilizing people around a convincing vision of the future, inspiring them to follow the steps of the leader. They show people what is possible and motivate them to make these possibilities come true. Leaders inspire and stimulate group members, convincing them to follow their vision, actions, ideas.

Leaders are followed because:

  • They inspire trust and credibility, proving an extraordinary capacity to develop relationships
  • They proficiently demonstrate competence and integrity, being models for team members
  • They have an attitude of valuing people, paying attention to them and their problems

Leaders energize the team and focus on people, give them a vision and a goal for their contribution to the company, which leads to a deep sense of fulfillment at the end of each working day. Leaders lead by shaping the ways of thinking or acting of colleagues, but also by encouraging new ways to look at situations. In this way, people give the courage to find their own WHY, as part of that WHY the organization.

Wrapping it all together

In many cases, leaders are also managers, and managers and many other colleagues in the organization are also leaders. The art of driving is knowing when to use authority and when to use influence, when to ask questions and when to express opinions or to communicate decisions, when to challenge challenges and when to blame behaviors.

As an entrepreneur, I have led teams of several people and teams of hundreds of people. Regardless of the situation or the size of the team, I have felt that my behavioral, communication, decision-making model was evaluated and transferred in varying proportions and different ways to the team, whether I wanted it or not. That’s why I chose to work constantly with me so I can propose my best version as a model, always keeping the courage and ability to be both authentic and human.


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The Energy Source

Plugging you into the latest from ENERGY STAR

Room-by-Room Savings: The Laundry Room

mom and son doing laundry

The Lawrence Berkeley National Laboratory found that homeowners typically spend about $2,000 every year on their energy bills. We’ve put together a series of posts that will show you how to save energy in your home, room-by-room.  Today, we’ve compiled tips to help you save energy and money while doing the laundry. To continue learning about energy-saving tips in the rest of your home, take a look at our room-by-room series.

Appliances: When replacing your clothes washer and dryer, look for the ENERGY STAR.

  • Clothes washers that have earned the ENERGY STAR use about 45 percent less water and about 25 percent less energy. A new ENERGY STAR certified washer will save you about $45 a year on your utility bills compared to a standard model.
  • Replacing your old clothes dryer with an ENERGY STAR certified model can save you $245 over the lifetime of the product.

Energy-Efficiency Settings: Make sure your appliances are set to the most energy-efficient options.

  • Heating water uses electricity. By washing your clothes in cold water only, you’ll save on heating costs—about $66 per year.
  • Program a faster spin speed to reduce the amount of drying needed and save $11 per year.
  • Use the lowest water setting to save more than 1,200 gallons of water per year.

Laundry Tips: Use these simple methods to save more when doing your next load of laundry.

  • Always wait for a full load to run the wash. Reducing the total number of loads each year by 25% could save you 3,227 gallons of water.
  • Clean the lint trap between loads—this improves air circulation and increases the efficiency of the dryer.
  • Air dry clothes outside during warmer months or on an inside drying rack to save energy from using a dryer.

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LG teases its new quad-core superphone: Snapdragon S4 Pro is awesome, device still vague (video)

While Qualcomm let the Snapdragon out of the bag a little early, LG's now caught up and launched a (Korean-only) teaser site for its next LTE smartphone. Promising a second-generation quad-core experience, the new flagship device will offer better power management and graphics performance thanks to the Snapdragon S4 Pro chipset beating away at its core. There's space on the site for another five videos, which should hopefully give us a little more detail than what we've been able to glean from FCC filings. Thumb your Korean dictionary ready and check out LG's first taster after the break.

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15 Solar Panel Output Hacks (That Boost Efficiency FAST)

15solarpanel.jpgImagine if you could make one simple change that would make solar power more affordable AND scalable.

What if this change gave you the ability to slash more energy bills, get paid more by utility companies, and battle climate change that much more?

Or even better:

What if you had 15 of these actionable high output solar panel ideas…

…And each of them generated more for your (and Earth’s) bottom line?

Luckily, that’s exactly what you’ll find today’s post:

15 incredibly practical solar panel output strategies that you can use to get the most value from your solar panels & accelerate solar energy use TODAY.

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Growth Strategies

Power Rangers

They're just your average tech moguls--saving the world, one power strip at a time.
8 min read

Go Forward Action Plan

  • Have the courage to start anew.
  • Have a vision.
  • Strive to understand what people want.

If they were going to save the world, there was something missing from the equation. Gary Grossman was having lunch with longtime friends and colleagues Robert Tatsumi, Peter Santangeli and Jonathan Gay. It was 2006, and the four had recently left their jobs at Macromedia, the company that eventually took over Flash before it was purchased by Adobe Systems in late 2005. Self-proclaimed tech geeks (and world-proclaimed tech geniuses), the creators of Flash could hardly be expected to spend a future sequestered to family life. Each had come from vastly different backgrounds, yet they'd spent most of their lives up to this point devoted to the same goal: making Flash a success. Now they had a new problem to solve: build a system to combat the energy crisis, save people money and educate them on the power of energy awareness, roll it out to utilities and millions of other clients around the country, watch the dough roll in and possibly save the world. All they needed was Grossman's OK, and Greenbox would officially begin.

Blocks away, Matthew Smith was mulling over a similar quandary. He had spent his career introducing revolutionary technology to an eager public, but he wanted something more. "I had worked on some really cool products, but they weren't necessarily making the world a better place," says Smith. "Some were probably even part of the problem." Now, with an MBA in sustainable management, he wondered how he could apply his background in technology to sustainability. Then the light went on.

The (Not So) Secret Lair
"We like it when people take public transportation," says Smith, 41, as he pulls up to the San Bruno, California, BART station. At 11:30 a.m., the station seems more akin to a scene from a Western than a bustling transportation hub for Silicon Valley startups. Within minutes, we arrive at the Greenbox building. The surroundings are humble compared with how the company aims to change the future of energy. The conference room, just days old when I arrive, is outfitted with a small brown couch, two white chairs and a coffee table, plus a projector that disappears every Halloween for Santangeli's neighborhood house decorating contest. It's as if they're constantly moving into this space, which they've actually occupied for two years now.

There are more important matters than redecorating at stake here: for one, changing the way people use and understand energy. "We're calling it interactive energy management," says Smith, Greenbox's vice president of marketing. "How do you get [homeowners] more engaged with how, where and when they use energy and give them the tools to make better decisions?"

Smith was the last to join the Greenbox team. While each member of the team plays a critical role in the success of this technology, Smith's contribution is perhaps the most vital. It's his job to make sure Greenbox is picked up not only by Flash proportions (which Santangeli tells me is now installed on more than 1 billion PCs and devices) but also nationwide--perhaps even worldwide. We settle into the conference room, and with a confidence that says he's done this many times before, Smith begins to impart to me exactly how Greenbox plans to save the world.

The Plan
The 2-year-old company is at the far end of the problem of turning energy awareness into consumer action. "Utilities have their backs against the wall in looking at what the demand for electricity is over the next five to 10 years," Smith says. "In most cases, it's outstripping what they have planned in terms of their generational capacity. There's a general feeling that they can't build their way out of this problem."

Greenbox's solution is much like a game, meant to help consumers understand their energy usage and how they can save money. To do this, the company is partnering with various utilities around the country to provide real-time data to consumers. A simple user interface at lets users choose between various functions, including a basic overview of the energy being used in their home, the price of electricity, usage by day and month, an interactive timeline, rate structures and usage alerts.

One can't help but wonder about the future reaches of this technology, which appropriately embeds Flash graphics and is so far is available in a basic and advanced version. Recently, it rolled out with a number of utilities after a successful trial run with Oklahoma Gas & Electric. The team plans to integrate smart appliances with smart thermostats that can adjust automatically and let neighbors compare home energy use with one another. A bit further off: electric carports and electricity bills priced like cell phone plans.

The Superheroes Unmasked
When I finally meet the rest of the team, I'm struck by how down to earth they all are. Santangeli, 43, is the most outgoing of the crew. As a key engineer for Greenbox, he's seen the technology evolve at least half a dozen times since launch. He admits with a sudden seriousness that much of that innovation would be null without the other founders. "Any company, any product is a series of problems," says Santangeli. "You start with the customer's problem, then you find a solution. And that solution implies a whole bunch more problems you have to get through."

In many ways, it was a series of problems that brought the five of them together. It just so happened that the problems each camp was desperately trying to solve were one and the same. So it was no surprise that when Smith was introduced to Santangeli and Gay--each an industry legend in his own right (at 16, Gay created Dark Castle, one of the first games for Macintosh computers, while Santangeli built a name for himself as one of Macromedia's star engineers)--the three instantly hit it off. "It just felt like complete kismet at some level because I was making this business plan and had a lot of ideas, but I'd never been an engineer," Smith says. "And then when I met these guys, I was struck by their insight and understanding of how to quickly bring a product to market. They've done it so many times that they don't waste their time on mistakes they made 10 years ago."

In a way, they are characters in a story they've already written. Each has his own superpower: Gay, 41, is the visionary; Santangeli is the engineer; Tatsumi, 46, is the catalyst; Grossman, 34, is the creator; and Smith is the voice. Yet, without the others, the ideas would stop and Greenbox would grind to a halt. It helps that most of the company's team of nine were actually former employees of Macromedia. Even one of Greenbox's primary investors, Rob Burgess, was once CEO there.

But more than their connection to one another is their unequivocal desire to be almost modern-day superheroes, breaking out of their tech geek shells to solve the world's problems. "When you're 50, you want your kids to look at you and say, 'Dad, you did good,'" says Santangeli. "[Greenbox] was an opportunity to leverage what we know and be a force for good in the world."

How Greenbox Thinks Outside the Box.
Have a vision. Gary Grossman grew up watching his parents build their computer programming company from the ground up. While things never took the way Flash did, his parents found their own level of success. "I thought, 'Hey, you can make it on your own,'" says Grossman. "It just takes persistence and determination."

Have the courage to start anew. After years under the Flash umbrella of success, fathoming a new, riskier venture wasn't easy. "It's hard to leave something that's a success," says Jonathan Gay. "But this was an interesting new problem space where we thought we could learn something."

Understand your customer. For Gay, starting Greenbox was as much about creating a new interface as it was about "not just being computer geeks." So Gay and the team set out to really understand what consumers wanted. "It's not just about how much energy you're using," says Gay. "It's also about understanding the emotion and ways [customers] can digest it."

Know the art of what's possible. Innovation is not just a side effect for the Greenbox team--it's a way of life. "We don't feel limited by what you can do with a box or a button," says Peter Santangeli. "We think, 'How should it work?'"

Think about your product. The Greenbox team critically thinks about each new addition and is quick to redefine the product even if it hurts. "You have a lot of close starts," says Gay. "You have to be agile. You have to be willing to change ideas."

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How to Get the Top 4 Percent of Your Customers to Buy 16 Times More


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Business Credit Cards Kick Up Rewards

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Business Credit Cards Kick Up RewardsUsing business credit cards isn't just a good way to keep your personal and your business finances separate, it might also be extra rewarding.

As the market for consumer credit heats up, and zero percent teaser rates have returned, issuers are stepping up their game for small business cardholders as well. Credit card issuers are taking more of a "carrot" approach to enticing new cardholders -- offering enhanced rewards and introductory offers.

American Express today announced its new Business Gold Rewards Card, a charge card that offers two rewards points for online advertising, gas and shipping spending up to $100,000 per calendar year per category. The card, which is expected to launch on Monday, also offers three points on airfare purchases and waives the $175 annual fee for the first year. Previous iterations of the card offered just one point per dollar spent. In June, AmEx started allowing users to redeem their Membership Rewards points toward the purchase advertisements on Facebook.

Just yesterday, Capital One launched a small business card that offers 2 percent cash back on every purchase. The card, which is called Business No Hassle Cash Premier, has a 13.9 percent variable annual percentage rate and a $59 fee that's waived in the first year. Although there's no cap on the amount of amount of rewards you can earn on purchases, note that to receive cash back more frequently than once a year, you need to set up a redemption schedule. And though the rewards never expire, if you close your account, your accrued rewards will vanish.

Capital One also launched an interest-bearing small-business card called Clear Interest Business Checking in July. That card offers one year of interest at varying levels depending on where a business is based.

"What we've had is a freeing up of credit in terms of limits and account access," says Curtis Arnold, the founder of credit education web site "There are dark clouds on the horizon, but if I'm looking from a small business owner's standpoint, I would jump at the opportunity to apply for a business card, provided the offer is good and the interest rate is average."

But business owners should still be skeptical of these cards. For months, small-business and consumer advocates have been angling for business cardholders to receive the same protections that consumers receive under last year's landmark credit card law. Though, their efforts haven't yet panned out. The concern is that business cardholders who don't get these protections might fall victim to predatory credit offers, hiking rates on past purchases, shifting payment dates or charging over-limit fees.

Shortly after the law passed, a number of banks including Bank of America, Capital One and Chase passed along select consumer protections to their business cardholders. Those moves were seen as efforts to stave off a large scale defection from business cards to consumer cards. Although consumer advocates say that consumer cards are still the better of the two credit genres because there's no way to guarantee that banks won't simply change their business card policies down the road.
What sweetened small-business rewards have you spotted recently? Leave a comment and let us know.

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4 Pieces of Financial Advice Every Budding Entrepreneur Needs to Hear


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How Companies Can Leverage Influence to Create Trust

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Entrepreneur | CEO | Speaker | Author | HR and Tech Evangelist
3 min read
Opinions expressed by Entrepreneur contributors are their own.

In recent times we’ve seen things crack the foundations of trust -- both online and in real life.

Facebook’s incredible morphing privacy policies (and experiments), unimaginable data breaches, revelations that Snapchat snaps don't really disappear, and of course Assange, Snowden and the NSA. The list could go on.

Despite these betrayals, our trust on the Internet, along with the ranks of online influencers, seems like it is continuing to swell. That coupled with the push we are seeing in the workforce – more millennials entering it and having their own definition of trust and influence – is making this an interesting time.

Related: Facebook: When Trust Is Exploited

Positioned squarely in the middle of the divide between employers and employees (and consumers and brands) is a new rank of what Benjamin Edelman, writing in the Harvard Business Review, terms  ‘intermediaries’: the platforms consumers and, in this case, employers and prospects, rely on for basic information. For instance, consumers turn to GrubHub for food choices, delivery and reviews. Companies and people look at job-community website Glassdoor for information pertaining to employers. We have come to a position of guarded trust in these platforms. But much could change.

This shift to a new understanding of who, or what, is trustworthy has huge implications for employers, especially as Boomers’ retirement rates pick up, creating job opportunities for Gen Y and millennials

So how do employers build trust and create influence, when so many other sites and services are competing for the same space?

Trust in online influencers and brands is really nothing new. Since Trout & Ries wrote about branding and positioning many decades ago (well before Mad Men taught us about the risks of believing in brand constructs developed by people three sheets to the wind) we’ve known, instinctively, when we’re being played. What changed our "Spidey sense?" Rewards. It turns out many of us are willing to give up a stunning amount of personal information for let's say a 15 percent discount or some free samples. Employer brands can’t give out lots of samples, really, so how do they play?

Related: 4 Ways to Build Trust Quickly

Employer brands skip the cursory rewards and turn to influence.  By creating gravity around their brands with content, employee advocacy and social buzz, they come to occupy a place in the minds of prospects and even passive candidates.

Doesn’t your heart beat a bit faster when you’re contacted by a recruiter for Google? Google has massive influence, even if it does not have absolute trust. And there, my friends, is the boundary between influence and trust. Trust must be earned, influence can be bought.

The task for employer brands, then, is to first create influence, then guard it well and expand it until it becomes trust. Trust doesn’t necessarily trump influence, but they are very closely linked.

Internally, companies must build corporate cultures of storytellers. Employees are your best, most loyal, most informed brand ambassadors. Their experience of working in your company is encoded in stories they tell to other employees, to prospects and the world via social networks. Support them as you would any other aspect of tour corporate culture to reap the rewards of influence and build networks of trust.

Related: Gaining Customers' Trust Can Be Your Checkmate

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7 No-Brainer Strategies to Close More Sales by Getting Customers to Trust You


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Steve Mackie's BSUQ Wants To Help You Start Your Business In Qatar

Steve Mackie's BSUQ Wants To Help You Start Your Business In Qatar
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Guest Writer
11 min read
Opinions expressed by Entrepreneur contributors are their own.

You're reading Entrepreneur Middle East, an international franchise of Entrepreneur Media.

The tiny Arab Emirate is investing its large revenues from oil and gas in other economic sectors in order to expand its economic base and develop a strong private sector. Qatar has opened other sectors of the economy to foreign participation and has relaxed business regulations in recent years to attract foreign investment. According to Qatar Development Bank (QDB), Doha offers a wide range of incentives, including subsidized or nominal rates for gas and electricity, no import duty on machinery, equipment and spare parts for industrial projects, tax exemptions on corporate tax for pre-determined periods, and no export duty. Other benefits include tax-free salaries, and state of the art telecommunication facilities. Business Start Up Qatar ( assists and facilitates foreign investors to successfully start their business in Doha by handling the various company formation procedures including required legal processes.

"The idea to start began shortly after an unsuccessful attempt to establish my first venture in Qatar. I saw great opportunities in the market and became keen on launching a close protection and event management services company. I soon discovered that starting a business in Qatar entailed unclear, time-consuming, high costs and above all frustrating procedures. Along the way, it became apparent to me that the commercial registration (CR) process alone was deterring potential businesses, both local and foreign, from entering the market. In fact, 10 months into the process I had lost a substantial sum of my investment capital without successfully incorporating my business," recalls Stevie Mackie.

As a result, Mackie started in 2009 as a guide for foreign investors interested in starting a new business or expanding to Qatar. "As more and more people approached us for help in setting up their business we decided to commercialize. We registered as a company formation specialist named Solutions Four after discovering that the regulations prohibited using the Qatar in a corporate name. Since then, as part of Solutions Four, has grown to become a one-stop shop to help entrepreneurs, startups, and business-owners in all aspects of starting their venture in Qatar." Finding the right contacts for guidance through the formation process was a major challenge. "We didn't understand the local culture and customs at the time and became frustrated when we were given assurances without real results. The cost of registering our business was another key challenge. We were left waiting on the long incorporation and licensing process without any incoming revenue. Moreover, finding a local partner, a requirement for most businesses, can be challenging for any newcomer to Qatar," says Mackie.

He continues to explicate how it is important for individuals looking to set up their venture in Qatar to immediately focus on getting their business off the ground. In other words, without the experience, knowledge and resources of a company formation specialist, incorporating a business and obtaining the necessary licenses and approvals can take months. "Moreover, it is crucial for any new business to be able to adjust to the cultural sensitivities of Qatar, whether it is marketing, creative design or company formation, Solutions Four can help businesses navigate the critical startup phase in an efficient and effective manner." While the challenges of incorporating a business are only temporary, the delays, lack of transparency, and inefficient systems are definitely frustrating for anyone. "One common grievance is the time required to obtain business activity approvals from the concerned authority."

When starting a business in Qatar, Mackie adds how one might be required to obtain approvals for the activities the business proposes- to undertake from the relevant ministry or mandated regulatory entity. This approval is often a source of major delay in particular for businesses in industries like healthcare and education. "One of the more challenging matters is obtaining ministerial authorisation for 100% foreign ownership in any of the 12 exempt sectors outlined in the amendment to the Foreign Investment Law. According to the amendment, first introduced in 2010, these 12 sectors -which range from agriculture to entertainment services- are eligible for the exemption if they contribute to the development of Qatar," Mackie details. "However, establishing the fulfillment of this condition is difficult. The exemption also requires ministerial approval, which is completely at the discretion of the concerned minister. Moreover, there are no detailed guides of eligibility criteria for these exemptions."

Qatar welcomes foreign participation in all the various sectors of national economy with 51% Qatari participation. Conversely, in order to promote foreign investment the Qatari government has enacted a Foreign Investment Law, which permits 100% ownership of the share capital of companies developing projects in the fields of agriculture, health, education, tourism, information technology, and exploitation of natural resources and mining. The Ministry of Business and Trade meticulously reviews each case prior to approval, but the law does not allow a non-Qatari to participate in banking, insurance, commercial agency or real estate trading activities.

"Understandably, the ownership restrictions can seem off-putting for many investors who would like to retain control over their venture. However, there are many provisions we can implement to address an investor's concerns. Even profit distributions and liability can be adjusted to the investor's needs. What many investors do not realize early-on is that having a reputable local partner can actually benefit your business. Many businesses use silent partners, but at BSUQ we encourage our clients to work with an active local partner who will work towards the benefit of your business by finding investors, corresponding with government officials and promoting your product or service."

At present, the Qatar Science and Technology Park (QSTP) and the Qatar Financial Centre (QFC) are the only two active free zone entities. Both allow 100% foreign ownership, licensed onshore trading, as well as unrestricted repatriation of profits and capital. QSTP is open to businesses involved in technology development and related activities in four areas: Energy, Environment, Health Sciences, and ICT. Also, businesses incorporated within QSTP have access to support services in addition to world-class office, laboratory, and training facilities. Technically QFC is not a free zone, instead it licenses businesses operating in financial services and related consultancy to do business in Qatar and abroad. QFC entities follow an autonomous regulatory regime that follows English Common Law. "An additional benefit of operating under QFC is that the business is not restricted to the physical premises of the QFC and can set up a physical presence anywhere in Qatar.

A key distinction between the two is that QFC has a relatively low 10% corporate tax rate on locally-sourced profit while QSTP firms are fully exempt from taxes. That being said, while both entities are open to everyone they appear to be predominantly occupied by large international firms with few small businesses and even fewer entrepreneurs," explains Mackie. In addition, the Special Economic Zones Company (otherwise known as Manateq) will be the flagship free zone entity in Qatar when launched. "The initiative comprises of three specialized zones, Ras Bufontas, Al Karaana, and Um Alhoul, which each cater to target sectors ranging from healthcare to petrochemicals. The zones will provide in-house administrative, immigration, and financing services. Collectively, the three economic zones are envisioned to serve as a hub for local industry and manufacturing," adds Mackie.

Another noteworthy initiative is the Student and Alumni Free Zone; this proposal is led by Roger Griffiths, Director of Entrepreneurship of Qatar-based Virginia Commonwealth University, and aims to establish a free zone for students and alumni of Qatar Foundation universities, Qatar University and other higher education institutions within the nation. "The initiative entails a pre-incubation support program that would allow students and alumni to develop their business idea into a micro-business without going through commercial registration. Those enrolled in the program will have access to working space, seed grants up to QR50,000, mentoring and a range of business development services while being able to operate their business virtually."

In recent years, Qatar's infrastructure, hospitality and real estate developments prior to the World Cup 2020 and the country's National Vision 2030 has attracted a large number of foreign construction and sub-contracting firms. The country's thriving economy has drawn in an influx of foreign businesses from around the world. "We've also seen the construction boom spur marine-based developments given Doha's prime location on the Arabian Gulf. Likewise, the many conferences and expositions hosted here in Qatar have prompted event management firms to expand their operations to Qatar. Other notable sectors with strong foreign presence include IT, education, and healthcare services."

The country has also freshly witnessed a shift from foreign- established businesses to local innovative business startups. "A startup scene has begun to emerge in Qatar as the local entrepreneurial ecosystem develops, and more support agencies offer assistance to young and aspiring entrepreneurs. While the innovative startup scene is still in its infancy, we've seen a strong presence from the service sector particularly from the ICT industry," continues Mackie. "Most aspiring entrepreneurs do not have access to external financing and office space. As such the relatively low set-up and operating costs of a tech startup combined with the prospect of high-value added margins make the ICT industry an easier market to break into. There is also a cultural dimension, the great success and social impact of tech startups in Silicon Valley has influenced local entrepreneurs to follow suit."

Referring back to having a local partner owning 51% of the business by law, Mackie explains how not always the highest earning partner invests in the business. "While it varies from one venture to another, the investment capital is usually paid in full by the foreign investor. The common local practice is for the business to employ a silent partner who does not partake in the activities of the business and receives a fixed fee for their role as a sponsor and the majority shareholder." Mackie explains that some of these arrangements fall into a grey area of the law, and this remains to be the most prevalent mode of conducting business in Qatar. "This is not to say that there are not cases where an active local partner contributes his labour and commits his financial resources as well."

Conversely, West Bay, which acts as the business and finance district of the capital, stands as the most desired location for businesses. West Bay hosts numerous world-class facilities and enjoys the status of a prominent upscale district, which in turn attracts many leading international firms. Other popular locations are C Ring Road and the Old Airport area. BSUQ usually refers their clients to serviced office providers such as Servcorp and Regus, which have offices in these areas. "Renting a serviced office may seem like an expensive option, but it may offer good value if you take all the included support services into consideration. Using a serviced office will also save you the hassle of obtaining a civil defence approval for the property. Most serviced offices are pre-furnished, come with trained receptionist and administrative staff, and include access to offices in most major cities," adds Mackie.

In accordance to BSUQ database of clients, the United Kingdom, Latvia, India, Canada and the United States are the top recent countries interested to invest in Doha. "With the slow economic recovery following the global financial crisis the political stability and double-digit economic growth of Qatar gives confidence to investors and business-owners alike. While investing in Qatar does present some formidable challenges there are unparalleled opportunities here. In fact, Qatar has the potential to become a hub from which businesses can expand into the region and beyond."

The Qatari government is trying to facilitate ways to attract foreign investors and achieve their overall goal of being the business hub of the Gulf, but without a doubt, Dubai remains a top choice for investors with its reputation as the easiest place to do business in the region. Dubai also ranks 23rd globally according to the 2014 World Bank Doing Business report. However, investors will find it difficult to set up a profitable venture in Dubai given the level of competition in the Emirati market. In contrast, the Qatari market is in its earlier stages of development, much like Dubai a decade ago, meaning that that there are still opportunities for investors to set up their ventures and establish industry leadership of their segment.

Basically, the time is right to head to Qatar for 'treps looking to get a leg up in the region. Mackie highlights the benefits: "Qatar has experienced phenomenal economic growth, enjoys political stability, and was recently upgraded to emerging market status making it a rare opportunity for business-owners and entrepreneurs alike."

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How This Health Insurance Startup Found Its Light Bulb Idea


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Food Tech

Investors Crave For Lower Costs, More Variety From Food-Tech Startups

Investors Crave For Lower Costs, More Variety From Food-Tech Startups
Image credit: Shutterstock
Entrepreneur Staff
Former Staff, Entrepreneur India
2 min read

You're reading Entrepreneur India, an international franchise of Entrepreneur Media.

Food-tech start-ups have been under the scanner post start-ups like TinyOwl and Foodpanda saw a string of layoffs at their outlets.  Industry experts believe that there are various challenges that have made investors cautious about this sector. Amid turmoil and speculation industry insiders believe the most important cause of concern is “margins.”

Padmaja Ruparel, president at Indian Angel Network says the three challenges in the food tech space are healthy food, logistics and customer traction. A restaurant has to change every 18-24 months, from ambience, menu and other things.

Investments in the food-tech have risen to about 229 million in 2015 from 66.8 million in 2014 and the number of start-ups in this domain has also more than doubled to 431 in 2015 versus the prior year, according to data provided by start-up data analytics provider Tracxn.

Navin Honagudi, Investment Director at Kae Capital said investors will firstly want to know how does the start-up differentiates itself from the existing chains, sustainability, how does it plan to build a brand and marketing strategies. Honagudi says food tech start-ups today should continue to focus on profitability. “Obviously everyone looks to increase market share but that should not come at the cost of negative unit economics and lower profitability.”

Anand Daniel, partner at Accel Partners said that Swiggy is unique in its end-to-end approach. From curating the best restaurants to suggesting the best dishes in those restaurants all the way to ensuring timely delivery of food with their on demand delivery fleet.  They have streamlined the entire process using technology every step of the way, Daniel added.

Vaibhav Ali, founder and chief executive of Midnight Hunger says unit metrics or margins  is the key concern for investors in the food tech space.  Ali believes one must not go all out with funds. “You need to treat your investors money as your money.” He also said that people in this sector need to understand how to use their money wisely.” Investors concerns hover around scalability and how we are combining technology with the business, Ali added.“ I think the biggest question for everyone is what background do we come from, do we understand the hotel business, do we understand what it really takes to build a great restaurant.”

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How This International Player is Set To Lead the Fight Against Obesity in India


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Costan, an Epta Group brand, is amongst the winners of the Marco Polo Award. The award, which is now in its 26th edition, is assigned by Unioncamere and the Foreign Trade Centre of the Chambers of Commerce of Veneto. It aims to nurture and promote the business activities of companies from Veneto that contribute significantly to the regional development of foreign trade in the industry, craftsmanship, agro-food, tourism and service sectors respectively.

The ceremony will take place in the headquarters of the Treviso-Belluno Chamber of Commerce on 14 December and William Pagani, Group Marketing Director for Epta will attend the event to collect the prestigious award.

Specifically, Costan was chosen for its excellent performance in the Veneto economy through its strong export focus and the impressive results obtained abroad during the course of 2015. Moreover, the Jury appreciated the constant growth of a brand that has been an international benchmark in the refrigeration sector since the ’70s. In this regard, exports are a key driver for Costan, as confirmed by the figures: 80% of 2015 turnover comes from trade with European and non-European countries. These results were made possible through the Epta Group’s constant investment in innovation with the objective of combining the excellence of its products with low environmental impact growth and, on the other hand, by the presence of a widespread sales network comprising branches and distributors all over the world.


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ER Computing believes that being a good business is also being a good neighbor.  That's why we're proud to offer discounts to people who need them. Discounts are valid on labor only.

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Erasmus Student Network Czech Republic (ESN CZ) is a non-for-profit student organisation representing local ESN sections on the national level. Our mission is to foster student mobility in Higher Education under the principle of Students Helping Students. All together sections of ESN CZ help roughly 10 000 international students every academic yearESN CZ represents international students, thus provide opportunities for cultural understanding and self-development.

ESN International:

We are 15 000 members from over 525 local sections in 40 countries working on a volunteer base in Higher Education Institutions. We are offering services to 150.000 students.
For more information visit


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The Write or Die Chick: The Challenge to Trust White Folks Post-Trayvon

Janelle Harris shares how she's trying to make sense of the George Zimmerman verdict.

Janelle Harris Jul, 22, 2013

The aftershocks of injustice make us ache for change. In the heightened emotional atmosphere following George Zimmerman’s brief cycle through the legal system, we’re communally outraged but unfortunately, not surprised.

The night the verdict was announced, I was on my way to dinner with friends and afterwards, we planned to see the Kevin Hart movie. The news broke on the radio and by the time I got to the restaurant, nobody was in the mood to laugh at him or anyone else. Three Black women—two of us mothers, one of us with young sons—sat in a booth over otherwise delicious food trying to feel our way through the absolution handed down by one brown and five White women.

I couldn’t even be angry. I’d felt that feeling so many times before, as a journalist digging through stories that reeked of onesidedness, as a sister who did her time in corporate America, as a citizen of the world who’s both confronted and witnessed venomous discrimination. I was more exhausted than anything, to the point where my shoulders actually slumped over my meal. (And I don’t never, not ever slouch over shrimp.)

Zimmerman’s vindication—and the proving right of his supporters—was another insult added to injury and, to fan the flames of my simmering bitterness, my memory swelled with ugly experiences I’ve personally had with covert and overt racism.

The time I was told to wait outside of a friend of a friend’s house because his father didn’t allow Black people inside.

The time in high school when Scott Davis called me a “porch monkey” in the middle of a packed cafeteria.

The time I sat in a pizza joint with my best friend when, out of nowhere, another patron started hollering about lynching niggers, and the owners did nothing about it.

The time I started a new school, which is hard enough, only to discover very quickly what it meant to be the 6th Black kid in a student body of more than 1,600.

The time I learned that that experience included being automatically carted down to special education, even though I’d been in gifted and talented classes since 6th grade.

The time some rednecks rolled up on me in an almost comically stereotypical pick-up truck, threw a can of Dr. Pepper at my feet and called me a Black whore.

The time the sales clerk shadowed me around Bloomingdale’s like she was on the heels of major crime prevention and couldn’t even be bothered to pretend like she wasn’t singling me out.

The time my former boss, who went to Yale, compared my alma mater to a community college because I went to an HBCU.

All the times I’ve been cut off in line like I didn’t exist, petted like Miss Sophia’s kids in The Color Purple, imposed upon like I was a cultural ambassador of Blackness. A thousand offenses flashed by.

If you’re Black and you’ve lived in America long enough, you have to learn how to choke down varying degrees of racial snubs—that is, if you want to keep a job, operate in society and stay out from under the billy club of some slap-happy cop (who will, as history has taught us, be magically exonerated for beating the living daylights out of your tail anyway).

It’s an American inheritance, this patriotism that proclaims itself virtuous, ethical and accepting but is too absorbed in all kinds of other good ol’ fashioned -isms to actually honor its own melting pot vision. Out of necessity, you develop a resilience that equips you to survive inevitable run-ins with other folks’ hang-ups, misconceptions, stereotypes, prejudices, hurts, insensitivities and lazy attempts to understand the breadth and depth of race. It’s easiest for the majority to be dismissive at best, hostile at worst whenever racism is called out because it disrupts the false comfort that finally, in 2013, we’re all equal and we’ve all overcome. Blah blah blah.

I’m thankful I know good White folks in real life, who acknowledge the benefits bestowed upon them by default. Because times like this, when what’s right and fair and seemingly logical is denied actualization, my first reaction is to distrust. Be wary. Put my guard up. White privilege has allowed some members of the majority—because, despite what statistics might say, the ones making, enforcing and upholding the laws are the only majority that matters—to lull themselves into the false belief that they’re not affected by indoctrinated racism.

Yet going to happy hour with a Black co-worker, eating a Black colleague’s deviled eggs at the company picnic and saving a seat for a child’s dinner guest, who happens to be Black, doth not disprove the harboring of racist beliefs or the reaping of the inherent benefits of being White. I’d venture to say most White folks aren’t conscious of their privilege or their biases about race. But it flares up in times like these, when those who don’t have to deal directly with race deny its power to influence the outcomes of everything from job interviews to court cases just because it hasn’t personally impacted them. So it takes a conscious effort to be genuinely empathetic and aware, and that’s an investment too many White folks aren’t willing to make. (Shout out to my three White friends who have.)

A justice system that wasn’t designed to protect Trayvon Martins in the first place failed to render a decision that shows off this sparkling, shimmering, new post-racial America we keep hearing so much about. We want so bad for this to be a teachable moment: tell your sons not to do this, warn your daughters not to do that. But there’s no way we can prepare for every potentially volatile, racially charged situation. I feel unprotected and disposable, double that for Black men. I’m trying to check my bitterness, though. If Sybrina Fulton and Tracy Martin can be diplomatic and dignified, I can at least try.

Janelle Harris is a writer, blogger and editor, and the owner of The Write or Die Chick , a boutique editorial services agency. She’s also a single mother, a proud Washington, DC girl and a longsuffering Kanye West fan. Chat her up on Facebook or Twitter.

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Get ready to experience entertainment like never before…

Welcome to the Best of EBOX…  Where you can find all the latest blockbusters…

  • Deadpool 2
  • Solo: A Star Wars Story
  • Life of the Party
  • The Seagull

Discover top rated TV shows…

  • Atlanta
  • Modern Family
  • Come Home

Tune into the hottest new music videos…

  • Clean Bandit – Solo

Sports results and the latest news…

(Clips from Sport 24_Sept)

Hundreds of hours of entertainment on demand… on E-BOX…

We have taken big-screen entertainment to the sky and you are in control.

  • Latest blockbusters, your favourites and timeless classics
  • Hollywood, Arabic, European, Indian and Asian Cinema
  • Multiple language tracks and subtitles

TV shows

  • Top-rated dramas and must-see comedies
  • Lifestyle, sport and documentaries
  • Drama Box-Sets
  • Ability to create your own video playlists

Live TV channels*

  • Live news update
  • Sporting action as it happens

*Available on selected flights only

  • Over 500 CDs in our library
  • Create your own audio playlists
  • 16 bespoke Radio channels
  • And much more

  • A selection of interactive games for all ages including a host of Android games on our B787 and A380 aircraft.
Children's movies

Our specially selected collection of animated movies, cool cartoons, music and interactive games will keep our young guests thoroughly entertained.

Our parental lock feature allows parents to block content.

Inflight entertainment

Enjoy hundreds of hours of entertainment!

  • Over 140 movies
  • More than 350 popular TV Shows
  • Full box sets of your favourite Dramas
  • 7 Live TV channels showing the latest news and live sport
  • LIVE sporting action on Sport 24 Channel
  • Extensive CD library
  • 16 Radio Channels
  • Up to 60 interactive games
Entertainment Guide

Entertainment Guide

What's on E-BOX this month

Keeping you connected

Onboard Wi-Fi*

You can purchase wireless Internet access using major credit cards or PayPal, buy a Wi-Fi voucher for cash or redeem a complimentary voucher.

Internet price plans start from as low as $4.95 and details can be found on the inflight Wi-Fi portal. If you are travelling in First Class you will receive 90MB of complimentary Wi-Fi access.

*Only available on selected Etihad Airways aircraft.

Use your phone to make and receive calls and text messages just as you do on ground.  If you have a smartphone with a data-roaming plan, you can access the Internet, your e-mails and popular chat apps.
Charges will be applied directly by your domestic mobile service provider and are similar to international roaming rates.

All our aircraft feature in-seat power so your devices never run out of juice.

Etihad Wi-Fly logo

We offer mobile and Internet services across our fleet* to help you keep in touch with friends, family and work while you fly.

Purchase a Wi-Fi voucher for cash from our cabin crew or connect to our onboard network to buy a Wi-Fi package that best suits your needs.

All major credit cards and PayPal accepted. Wi-Fi vouchers are also available for sale for cash onboard.

If you are travelling in First Class you will receive 90MB of complimentary Wi-Fi access.

Full details are available in the E-BOX entertainment section inside Atlas magazine or on the in-seat cards on connected aircraft.

*Internet is only available on selected aircraft


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Buy Tires in California Desert Hot Springs 92240

Shopping for new tires online?

All of us buy more and more on the web. However, there are still some product groups that we are more likely to buy in the traditional way. One are tires. A relatively small percentage of individuals still know that the Internet is the speediest and most convenient way to buy new wheels. What is the electric power of buying tires on the net?

Meanwhile, only in the network we certainly have guaranteed the most significant wheel offer with guaranteed supply and the possibility to take good thing about numerous promotions that will enable you to buy a set of new tires at an attractive price.

Contrary to appearances, when buying auto tires online, as in the case of purchase on the site, we have the possibility to use expert advice from advisors who will help you choose the best tires for our car. Generally, we can use an straightforward chat or helpline. Additionally, there are numerous guides on the main issues about the correct number of winter and summer four tires, as well as the introduction of tire testing. Professional know-how about the four tires is therefore easily available

When buying tires on the Internet, we also have the possibility to easily compare the models we are enthusiastic about and read the opinions of others. In addition, we may easily find a detailed information of the tire and basic advice about the manufacturer. Such information and the likelihood of assessment are in vain found at the supermarket wheel stand.

When buying wheels online, remember to buy tires in a known and proven store with a good reputation. This way, we are sure that we purchase new and original tires, having optimum properties and professionally stored in the right conditions.

For the purchase on the Internet speaks a sizable selection in one place, the possibility to buy at any time of the day or night without leaving your home or business, or finally the chance to compare offers and prices using specific services. A major good thing about online stores is the price. The price dissimilarities are usually between 15 and even 40% in their favor. Usually, the biggest disproportion occurs when buying tires from the top shelf. Why is the so big? The main reason is the simple fact e-stores operate on a larger scale than traditional tire factories, and scheduled to high turnover of goods and intensive strategies, they can afford plainly lower prices. Also, the costs of maintaining a sizable number of staff and the premises where the company is located are also lost. An important good thing about buying online is the offer, which in turn includes almost all manufacturers.

The purchase of automobile is, naturally, only 50 percent the battle. New auto tires need to be installed in the car. The set of four auto tires weighs about 30 kilogram and causes a whole lot of transport problems. The very best online websites to get tires have considered care of customer enjoyment at this stage of sales – they incorporate the convenience of purchasing on the site with all the features of buying wheels on the Internet.

Mainly because of the internet, the purchase and replacing auto tires cease to be time consuming and cumbersome activities. The whole process can be done behind the computer screen and in a dozen or so minutes to choose and purchase tires that will best suit our expectations.


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ETSI and VRARA cooperate on Virtual and Augmented Reality

Sophia Antipolis, 9 November 2017

The US based VR/AR Association signs Letter of Intent with ETSI

ETSI is pleased to announce that the Virtual Reality/Augmented Reality Association (VRARA) has recently signed a Letter of Intent to collaborate on interactive VR and AR technologies delivered over emerging 5G networks and hosted on Multi-access Edge Computing sites.

VRARA will be primarily involved with ETSI’s Multi-access Edge Computing group.

Virtual and Augmented Reality technology holds the promise to fundamentally transform how people interact with and experience the physical world, how they are entertained, and how services are delivered to them.” states Alex Reznik, ETSI MEC chairman. “We are at the cusp of this transformation, and, yet, it cannot happen unless the networks that will have to support these applications can deliver the required performance, e.g. latency on the order of several milliseconds. Edge computing is necessary to deliver such performance; while mobile networks, which today already provide pervasive global connectivity, are likely to continue occupying this central role.

The partnership between ETSI, the home of the world’s leading Multi-access Edge Computing standardization activity and VRARA, the world leading industry association representing the Virtual and Augmented reality industry recognizes the need to bring the two communities together. This cooperation will encourage common member companies to pursue VR/AR focused use cases and requirements for ETSI MEC Phase 2 so as to ensure that the resulting specifications address the needs of this key industry sector. VRARA will support adoption of ETSI MEC work as appropriate and highlight benefits of Edge computing to VR/AR solution developers.

In a recent research report we’ve published, we learnt that enterprise AR & VR have more receptive buyers than consumer markets, due to a strong ROI case.” says Kris Kolo, Executive Director of the VR/AR Association. “Working closely with ETSI which expertise lays in all ITC related sectors makes sense. We’re really excited to start this collaboration with their MEC group.

About ETSI
ETSI produces globally-applicable standards for Information and Communications Technologies (ICT), including fixed, mobile, radio, aeronautical, broadcast and internet technologies and is officially recognized by the European Union as a European Standards Organization. ETSI is an independent, not-for-profit association whose more than 800 member companies and organizations, drawn from 68 countries across five continents worldwide, determine its work programme and participate directly in its work.

For more information please visit:

Claire Boyer
Tel: +33 (0)4 92 94 43 35
Mob: +33 (0)6 87 60 84 40
Email: [email protected]


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Whoa! You can't buy your own item.

BICONE 4 mm crystal blue N56 25

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Add it to your favorites to revisit it later.

Sorry, we could not translate this listing to English.
set of 25
size 4 mm
color blue
Visit my shop for the selection and quality products
Order to shipping speed and low prices
Appropriate shipping costs to each product in normal followed or colissimo you can choose
Your faithfulness is rewarded
Any questions I remain at your disposal
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BICONE 4 mm crystal blue N56 25

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  • Handmade Supply
  • Craft type: Beading, Jewelry making, Kids' crafts
  • Bead size: 4 mm
  • Material: Glass
  • Favorited by: 2 people
  • Gift message available
This shop accepts Etsy gift cards

Ready to ship in 1 business day
From France

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Work with EUMCCI

Internship Opportunities

Who are we and what do we do?

Established in 2003, the EU-Malaysian Chamber of Commerce and Indust ry (EUMCCI) stands as a public non-profit organisation financed by projects, events, memberships, and corporate partnerships.

We aim to promote, support and develop EUbusiness interests in Malaysia aswell as facilitate trade, commerce and investments between the two trading blocs. We achieve this by carrying out social and business activities that will catalyse and stimulate networking of European companies in Malaysia with the Malaysian business community, business associat ions, relevant ministries, official representations,
and other Chambers in Asia.

What do we offer?

The EUMCCI offers 5 internships to students towards the end of their studies. The close-knit nature of the organisations allows interns to thrive and be a value adding-member of the chamber. The internships expose students to an international environment by exposing interns to the EU-Malaysian business community. The diverse activities of the EUMCCI allows students to walk away from the internship with new knowledge and skill development in various disciplines.

During the internship, the interns will work closely with amanager who will help guide and support the intern in their daily tasks to ensure that they thrive through their work. Successful candidates will be compensated with basic renumeration according to terms and conditions.

What are we looking for?

We are looking for Malaysian and European students to join us. They are mostly selected towards the end of their undergraduate or postgraduate studies.We look for students in the fields of Business, Economics, Accountancy, International Relations, Event Management, or Communications.

We are looking for independent and passion driven candidates who are not afraid to take initiative. Moreover, we are looking for responsible candidates eager to learn and develop their skills and competences. Strong organisational, communication and English language skills are appreciated. Student should possess computer skills including proficiency in Microsoft Office suite.

Candidate should be able to network with stakeholders during events.

How can you apply?

Please provide us with the following:

  • Latest Curriculum Vitae (CV)
  • A short Cover Letter
  • Contact detail & a recent photo
  • Preferred internship position
  • Availability for internship

Internship Position and Task Descriptions

  • Assist to organise and promote conferences, trade shows and events, e.g. IGEM2018, Europa Awards, Food Forum, etc.
  • Opportunity to join events of other stakeholders.
  • Assist to organise Trade Missions for European and ASEAN companies, and research for relevant companies for B2B matching sessions.
  • Assist to organise CEO's EU Outreach trip, to meet with associations and companies interested to explore the Malaysian market.
  • Keep in touch with other ASEAN Chambers to explore potential co-operations.
  • Manage Business Malaysia portal, consisting of important trends of different industries in Malaysia.
  • Assisting the EUMCCI Committees leadership & coordination between committees in terms of the direction and strategies of the advocacy matters for all the committees.
  • Keeping the committees active, up-to-date on issues and policies of interest, and assisting in organising activities that would help strengthen the committees.
  • Attend meetings and dialogues that are relevant to the committees.
  • Building contacts with various government departments and ensuring healthy government engagement.
  • Responsibilities include administrative tasks relevant to committee work.
  • Assisting the events manager in the management of EUMCCI events throughout the year.
  • Sourcing of new suppliers and ensuring prices remain competitive and are within the budget.
  • Management of speakers' logistical requirements and liaison with sponsors to ensure all aspects of the contract are met.
  • On-site logistical management of events.
  • Collect and analyse feedback from all events. Provide subsequent feedback for future events.
  • Assist extensively in marketing activities for events (telemarketing and, design of marketing material).
  • Assisting the Membership Manager in maintaining the EUMCCI membership database (consisting of European and Malaysian companies, bilateral chambers, and Malaysian government stakeholders).
  • Attend meetings with key decision makers of the member companies and stakeholders.
  • Involved in lead generation, new member acquisition and retention strategy.
  • Work closely with manager to come up with marketing collaterals, conduct surveys, and prepare analysis reports.
  • Responsibilities include administrative tasks relevant to membership tasks.
  • Report to the CEO and Finance/Admin Manager.
  • Prepare and initiate payments.
  • Help maintain office accounts by handling petty cash, checking claims by stakeholders and prepare purchase orders.
  • Obtain quotations from suppliers, prepare comparison schedules, arrange purchase orders, checking delivery orders and invoices.
  • Upkeep of office, meeting room, and room bookings.
  • Issuance of tax invoices & receipts.
  • Attend to guests and help out at events when necessary.
  • Oversee office holiday/leave records.

GET IN TOUCH Looking to start a project or trying to find us?

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Public Release:

Discovery of an unexpected function of a protein linked to neurodegenerative diseases

A study done on fruit flies and published in Nature Communications reveals that the protein dDsk2, in addition to degrading proteins, also plays a key role in regulating gene expression

Institute for Research in Biomedicine (IRB Barcelona)

IMAGE: This is a microscope image of polytene chromosomes from Drosophila melanogaster, in which, using staining techniques, scientists have visualized the protein dDsk2, a molecule never previously associated with chromatin view more

Credit: (image: R. Kessler, IRB Barcelona)

Barcelona, Tuesday 28 April, 2015.- Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double scenario, one focused on basic epigenomic research and the other biomedical, because of the link between dDsk2 and neurodegenerative diseases.

Double role of ubiquitin

In humans, there are about 100 proteins associated with ubiquitination, the process by which a protein labelled with ubiquitin is removed from the cell by specific cell machinery known as the proteosome. Ubiquitin receptors are involved in the detection of ubiquitination.

Ferran Azorín, head of the "Chromatin structure and function" group says, "although previous data pointed to the possibility of ubiquitin receptors also contribute to cell processes, data were scarce and a direct role in gene regulation had not been demonstrated."

"Ubiquitination related to transcription proteins and to DNA repair had previously been described. But this is the first time that a protein, dDsk2, that recognises the ubiquitination of a histone, a protein that forms part of chromatin, has been identified." Chromatin is a complex formed by DNA and histones --proteins tightly bound to DNA-- packaging it into chromosomes and determining gene expression, a process known as epigenetics.

Recent years have brought about the discovery of the fundamental contribution of epigenetics to the development of disease. "We have now opened a new perspective for ubiquitin receptors and we should further this research", explains Roman Kessler, a Swiss "la Caixa" PhD fellow at IRB Barcelona and first co-author of the paper. In the study, the researchers also reveal the molecular mechanism through which the protein dDsk2 binds to chromatin proteins, thus participating indirectly in the regulation of transcription.

The protein in neurodegenerative diseases

Subjects with Alzheimer's disease and other neurodegenerative pathologies such as Huntington's, have a mutation in the protein ubiquilin, the homologue of dDsk2 in humans. "The role of these mutations in the onset and development of disease is still unknown," says Johan Tisserand, postdoctoral research and co-author of the study who is continuing with the project. "Now that we have discovered this new function, we aim to study whether it affects degradation or transcription, although probably both processes are altered. Our goal is to work towards unravelling these effects," concludes Ferran Azorín. The new studies will be performed on Drosophila melanogaster and in cells in vitro.

Reference article:

The ubiquitin receptor dDsk2 regulates H2Bub1 and RNApol II pausing at dHP1c-complex target genes

Roman Kessler, Johan Tisserand, Joan Font-Burgada, Oscar Reina, Laura Coch, Camille Stephan-Otto Attolini, Ivan Garcia-Bassets and Fernando Azorín

Nature Communications (2015). DOI: 10.1038/ncomms8049

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.


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Network of networks / Research and Education

Amel Grami

Member since 07.03.2016

Presentation of research activity or teaching

Ms. Amel Grami is a professor in the Master of Women's Studies (for 6 years) and, this year, in the Master of Gender, Society and Culture at the University of Manouba in Tunisia. She also supervises PhD students that work on gender, from the Faculty of Letters, Arts and Humanities.

Mrs. Grami has participated in several conferences and she published a report on the progress of women's rights in the Arab world (Fikr Foundation 2014). Mrs. Grami works mainly on civil and political life, violence, health and effective and sexual life in Arab countries.

Mrs. Grami has over 10 years of specific experience working in gender equality.

Address : 39 Avenue Neptune 2046 Les Jardins de Carthage, 2046 ,Tunisia
Adress email :
Website :


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Home » Used cars » Used SEAT Cars In Devon

Why not try our Move me closer service?

Try our move me closer service, and benefit from our whole used car range across the UK. It’s easy, just search our used car offers, find a car you want, submit your Move Me Closer request by clicking the button under the 'Location' section of the page, pay a £200 refundable transfer fee and have it moved to your nearest location.  View and test drive the vehicle, if you are happy with the car we can then continue with the purchase.

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Used SEAT Cars in Devon

Evans Halshaw aim to help you find a used SEAT car in Devon that’s right for you. With a range of different SEAT models, you can browse our second-hand SEAT cars in Devon, and with our move me closer service, you aren’t restricted by location, as we can move any of our used SEAT cars nearest to you. Our price guarantee, also gives you peace of mind as we constantly review and update our used SEAT vehicles to offer you the best price. Explore online our used SEAT cars for sale in Devon, or find out more by calling our experts at Evans Halshaw on 0333 323 6434.


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Big Day Out 2009 First Line-Up Announcement

Tuesday 30 September 2008

Are you ready for the Big Day Out 2009's first official announcement?!

It's going to be huge, with the first installment of confirmed acts looking like this:

Neil Young, Arctic Monkeys, The Living End, The Prodigy, Sneaky Sound System, My Morning Jacket, Pendulum, Bullet For My Valentine, TV On The Radio, Simian Mobile Disco, The Ting Tings, Tiki Taane, Headless Chickens, The Black Seeds, The Datsuns, Elemeno P, Nesian Mystik, Luger Boa, Cobra Khan, Ladi 6, and The Naked And Famous!

Stay tuned for the second announcement of artists coming soon! Tickets go on sale Friday 10 October, from Real Groovy, Ticketmaster, and also the Big Day Out website (


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