system
A chat on subreddit /r/pcmasterrace
human
It's only been happening with this game so far, videos from YouTube Netflix or Hulu will flicker and I'll need to refresh the window to make it stop
gpt
Download GPU-Z and have that running (second screen if you can) and when it starts playing up check that your temps are ok.

If it's not a temperature issue that's setting off the strange behavior (and honestly I don't think it will be) I would say download DDU, display driver uninstaller and follow the guide on their website.
Fresh install of your driver software after and see if the problem continues.