system
A chat on subreddit /r/pcmasterrace
human
i guess if you were into competitive shooters not using the mouse with your dominant hand could give you an inherent disadvantage. I'm not a leftie and I'm just assuming.
gpt
As a lefty, I think it matters more how you’ve accustomed to it. I’ve used a mouse on the right since I could barely understand what I was doing. Using my left hand feels incredibly unnatural and keyboard mouse combination simply isn’t made for left-handed players. I’ve played plenty of CS:GO and while I was decent in competitive I don’t  think my hand was the limiting factor.