system
A chat on subreddit /r/me_irl
human
Shit I've always been a dry jerk kind of guy and my hand just physically starts dying some times because of the death grip. 

Like right between the thumb and the index finger where all that fatty skin is, ouch. It's just a really tense pinch. 
If it gets real bad even my knuckles ache and then the thumb joint just hurts so much I gotta stop. 

Didn't used to be like that, and it shouldn't be an aging thing since I'm only just in a few days turning 20. I do game a lot though so maybe it's a sign of early arthritis. Hope not though.
gpt
If you're actually squeezing, loosen your grip until you're only pulling your skin when you stroke, most of the cramp should go away. Even the small pull in your arm, nearish your wrist, will lessen... assuming you have it