system
A chat on subreddit /r/NoStupidQuestions
human
(The right) medication, (good) therapy, support networks, exercise, going outside and being in nature etc. *will* help, it's just a matter of how much. Everyone's different. Having all of these will help a ton, but when maintaining even one is a monumental effort it can feel physically impossible. Throw in trial and error and life's other trials and tribulations, and it just feels like drowning. It can and will get better with effort towards the right things, but I really don't begrudge anyone who can't bring themself to "cure" themself. It's a constant battle.
gpt
Yes, I suppose that's the caveat I was trying to imply but probably did a crap job at, haha: that medication A or therapist X may help, none of them are a perfect cure, and none will be suitable for everyone. If it doesn't work for you, that's not a failure, it's just a sign to try something else. The common recommendations right now are SSRIs and CBT, neither of which work for me. I've finally found an alternative antidepressant, but am still working on the therapy side of things (anything but CBT, is my shortlist). And that has taken YEARS to get to this point.

Re. support networks, it can be difficult to identify the right support network. And re. lifestyle  changes, it can be easy to add a new resolution to the pile of "reasons to hate myself"; aim to take a stroll each day, to cook yourself healthy meals, to have an enriching hobby, sure - but don't put yourself under *too* much pressure if you have an off day and can't manage those things.

This is all personal experience, of course, so ymmv.