For decades, the city has boasted of: a "Big Five" orchestra (The Cleveland Orchestra), the second largest performing arts center in the U.S. (Playhouse Square Center), a world - renowned art museum (The Cleveland Museum of Art), the nation's nation 's first health museum (HealthSpace Cleveland), R&D hub of the aerospace and aviation industry (the NASA Glenn Research & Visitors Center) and a number of other first - rate attractions (too many to mention here - read on).