Peutz-Jeghers Syndrome   What is Peutz-Jeghers syndrome?  Peutz-
Jeghers syndrome (PJS) is an inherited condition that puts
people at an increased risk for developing hamartomatous polyps
in the digestive tract as well as cancers of the breast, colon,
pancreas, stomach, ovaries, and other types, listed below. The
lifetime risk of cancer in people with PJS is around 93%. A
hamartoma is a growth of normal-appearing tissue that builds up
into a benign (noncancerous) tumor. However, the benign tumor
can transform into cancer over time. Cancer begins when normal
cells begin to change and grow uncontrollably. A tumor can be
noncancerous or malignant (cancerous, meaning it can spread to
other parts of the body).  Typically, signs of this condition
appear in childhood with the development of pigmented areas on
the skin and in the mouth (called mucocutaneous
hyperpigmentation). People with PJS tend to develop dark blue or
dark brown freckling, especially around the mouth and on the
lips, fingers, or toes. Freckles gene