Funding opportunities  Kinase signaling analysis of iPS cell
reprogramming and differentiation  Funding Type:  Basic Biology
II Grant Number:  Principle Investigator:  Funds requested:  $1
447 956 Funding Recommendations:  Grant approved:  Public
Abstract:  Like embryonic stem (ES) cells, induced pluripotent
stem (iPS) cells can differentiate into every cell type in the
body, providing enormous potential for regenerative medicine.
Unlike ES cells, the derivation of iPS cells is more
straightforward technically, and can be performed on human adult
cells. This potentially obviates the need for donated eggs or
embryos, and permits the ability to generate patient-specific
stem cells for disease research, drug development, and new cell-
based therapies - generating great excitement in the scientific
community as well as with the public. iPS cells hold great
promise for regenerative medicine, but the cellular signaling
that controls their derivation and function remains poorly
understood. We are developing methods t