After seeing the film Dr. No, Joseph Barbera decided he needed
to make a high-tech adventure cartoon, and so Jonny Quest was
born. There have been three variations of the show since it's
inception, but the parodies spawned are uncountable.  Jonny
Quest: The Mystery of the Lizard Men  The New Adventures of
Jonny Quest: The Monolith Man  The Real Adventures of Jonny
Quest: The Realm of the Condor  The show The Venture Brothers
itself is a parody of Jonny Quest, but the Quest characters
actually show up on the program, for instance here when an older
Jonny makes one hell of an insult:  And remember the cartoon
Freakazoid? A segment called "Toby Danger" was the most spot on
parody of the franchise to ever be released: