Take the 2-minute tour ×  I've been reading the British National
Formulary 65 (BNF-65) and it mentioned that in some, especially
at higher dosages, sedating (first-generation) antihistamines,
can produce paradoxical excitatory (or stimulating) effects and
so I felt like asking the age-old question, "Why?" because as I
hope is obvious by my questions I am fascinated by drug action
and I felt there was no better place to ask this question than
here on biology stackexchange.  share|improve this question
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