Psychology Wiki   34,114pages on this wiki  Redirected from
(5-hydroxy) tryptamine    Template:Chembox InChI CAS number
50-67-9 PubChem 5202 MeSH Serotonin SMILES
NCCc1c[nH]c2ccc(O)cc12 Molecular formula </sub>C10H12N2O Molar
mass 176.215 materials in their standard state (at 25 °C,
100 kPa)  Infobox disclaimer and references   Function Edit
File:5-HT numbered.svg A hydroxy-group at carbon 5 of the carbon
skeleton of L-tryptophan without a carboxyl group gives
serotonin its descriptive chemical name, 5-hydroxytryptamine.
Levels of serotonin in the brain show association with
aggression [4], and a mutation in the gene which codes for the
5-HT2A receptor may double the risk of suicide for those with
that genotype.[5]   In addition, serotonin is also a peripheral
signal mediator. It is found extensively in the human
gastrointestinal tract as about 80-90% of the body's total
serotonin is found in the enterochromaffin cells in the
gut.[7][8] In the blood, the major storage site is platelets,
which collect sero