Email updates   Open Access Highly Accessed Research article
Structural characterization of CA1462, the Candida albicans
thiamine pyrophosphokinase  Sébastien Santini1, Vincent
Monchois2, Nicolas Mouz2, Cécile Sigoillot1, Tristan Rousselle2,
Jean-Michel Claverie1 and Chantal Abergel1*  Author Affiliations
1 Information Genomique et Structurale, UPR2589, Parc
Scientifique de Luminy, 13288, Marseille cedex 09, France  2
Protein'eXpert, 7 Parvis Louis Néel, BP50 38040 Grenoble, France
For all author emails, please log on.  BMC Structural Biology
2008, 8:33  doi:10.1186/1472-6807-8-33   Received:22 April 2008
Accepted:24 July 2008 Published:24 July 2008  © 2008 Santini et
al; licensee BioMed Central Ltd.     In search of new antifungal
targets of potential interest for pharmaceutical companies, we
initiated a comparative genomics study to identify the most
promising protein-coding genes in fungal genomes. One criterion
was the protein sequence conservation between reference
pathogenic genomes. A second criteri