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are here:Home » Antibodies » Abs to Enzymes, Endonuclease » Anti
-APE (Ref-1, Apurinic Apyrimidinic Endonuclease, APEX, APE-1,
HAP1)      For pricing information, USA customers sign in.
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Clone Host Grade Applications Polyclonal Goat Affinity Purified
E B Human APE (also known as Ref-1) is the apurinic/apyrimidinic
(AP) endonuclease required for efficient DNA base excision
repair (BER). Following the removal of a damaged base by a DNA
glycosylase, APE cleaves the AP site to allow resynthesis and
ligation to complete repair. In addition, APE/Ref-1 acts as a
factor that regulates the redox state of multiple transcription
factors, including c-Jun, c-Fos, NF-kB, and p53. Catalog
#A2298-74A1 Recommended DilutionWestern Blot: 1ug/ml Optimal
dilutions to be determined by the researcher. Clone
TypePolyclonal ConcentrationAs reported FormSupplied as a
lyophilized powder from a 0.2um filtered solut