Angina is a chest pain caused due to restriction in blood supply
to tissues. In India nicorandil is a vasodilatory drug used to
treat angina. The effect of this drug, nicorandil as a
vasodilator, is mainly attributed to its nitrate property. In
humans, the nitrate action of Nicorandil dilates the large
coronary arteries at low plasma concentrations. At high plasma
concentrations Nicorandil reduces coronary vascular resistance,
which is associated with increased K+ATP channel opening.