Table 1: Examples of Intrinsic and Extrinsic Factors
Magnitude, direction, duration, rate, and lack of variability of
work-related external forces affecting tissue stress/strain
history   Number, frequency and duty cycle of work-related
loading cycles affecting tissue stress/strain history  Tissue
anatomy - heritable factors, changes due to tissue injuries
during childhood/adolescence  Work-related postural requirements
affecting tissue stresses/strain history  Tissue physiology-
healing/remodeling potential; response to chronic loading
Availability of rest days  Tissue state-state of
hypertrophy/atrophy/remodeling as it affects relevant tissue
physical capacities  Leisure/commuting activities engendering
tissue stress/strain history  Muscle recruitment strategies,
related functional biomechanics   Response to psychological
stress   Response to pain state   Soft tissue injury triggers a
complex cascade of events involving an inflammatory response,
which marks the first phase of the healing response, a pro