Top Definition A syndrome that occurs in females who were
attractive for the beginning part of their life, but after high
school/college, their bodies burned out and now are considered
below average on the male attraction scale. Opposite of wine
syndrome. Person A: Great to be here at the high school reunion.
Person B: Hey, isn't that Angela over there?  Person A: Man,
she's disgusting now isn't she?  Person B: She must suffer from
cheese syndrome by JustThatGuy June 03, 2009 6 Words related to
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