[1694] Interstitial Eosinophilic Aggregates Is Distinctly More
Common in Diabetic Nephropathy Than Other Glomerulopathies
Kotaro Sasaki, Kelly Smith, Roberto Nicosia, Charles E Alpers,
Behzad Najafian. University of Washington Medical Center,
Seattle  Background: The presence of interstitial eosinophilic
aggregates (IEA) in renal biopsies is commonly interpreted as
allergic type tubulointerstitial nephritis (TIN-A). However, in
many cases, no significant correlation with a history of drug-
use can be found. Here, we studied the prevalence of IEA in
diabetic nephropathy (DN) as well as other common types of
glomerulopathy. Design: Diagnostic reports made by one
pathologist between January 2010 and August 2011 were reviewed.
The cases with DN (n=74) or other glomerulopathies including IgA
nephropathy (IgAN) (n=43), membranous nephropathy (MN) (N=40),
thrombotic microangiopathy (TMA) (n=14), amyloidosis (n=15),
focal segmental glomerulosclerosis (FSGS) (n=121),
membranoproliferative glomerulonephritis (MPGN) (n=