Multiparametric analysis of focal adhesion formation by RNAi-
mediated gene knockdown  submitted by: JCB Cell adhesion to the
extracellular matrix is mediated by elaborate networks of
multiprotein complexes consisting of adhesion receptors,
cytoskeletal components, signaling molecules, and diverse
adaptor proteins. To explore how specific molecular pathways
function in the assembly of focal adhesions (FAs), we performed
a high-throughput, high-resolution, microscopy-based screen. We
used small interfering RNAs (siRNAs) to target human kinases,
phosphatases, and migration- and adhesion-related... Authors:
Sabina Winograd-katz, Shalev Itzkovitz, Zvi Kam, Benjamin Geiger