Document Detail  Potential economic impact of increasing low
dose aspirin usage on CVD in the US. MedLine Citation: PMID: 
20738228     Owner:  NLM     Status:  In-Process     BACKGROUND:
Cardiovascular disease (CVD) is a leading cause of death in the
US and Western Europe, but regular use of preventive low-dose
aspirin has proven effective in preventing CVD events. The
purpose of this study was to explore the potential economic
impact in the US if preventive aspirin usage were to be
increased in line with clinical guidelines for primary and
secondary prevention. METHODS: The risk profile of the US
population was characterized using NHANES data, and Framingham
cardiovascular risk equations were applied to calculate risk for
myocardial infarction, angina and ischemic stroke according to
age and gender. Primary and secondary patients were considered
separately. Using publicly available unit costs, a budget impact
model calculated the annual impact of increased preventive
aspirin usage considering gastrointestin