Take the 2-minute tour ×  Is there any way of determining which
X chromosome a female inherited from her father and which from
her mom ?  share|improve this question You could try to follow
this up by sequencing the X chromosome from the father and try
to find unique polymorphisms which are not present in the X
chromosome of the mother. You can than try to find them in the
childs "X". This makes not much sense though, since one of the X
chromosomes is ramdomly inactivated. –  Chris Jan 25 at 11:11
@Chris So, we could use RFLP for this ? Could we also use FISH ?
–  biogirl Jan 25 at 11:24 RFLP could work, I am not sure if the
resolution of fish is good enough. –  Chris Jan 25 at 11:38
@Chris Thanks! I don't know much about FISH, so what exactly do
you mean when you say that resolution won't be good ? –  biogirl
Jan 25 at 11:41 For FISH you need a probe that binds to the
chromosome. If the difference you want to see is so small (a SNP
for example), that the probe will bind anyway, than the
resolution of the met