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Protein p88, IP90, P90) (Azide Free)     For pricing
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contact your distributor for pricing.   Clone Host Grade
Applications Polyclonal Rabbit Serum B IP IC Calnexin, an
abundant ~90kDa integral protein of the endoplasmic reticulum,
is also referred to as IP90, p88 and p90 (1). It consists of a
large 50kDa N-terminal calcium-binding luminal domain, a single
transmembrane helix and a short acidic cytoplasmic tail (2, 3).
Unlike its ER counterparts which have a KDEL sequence on their
C-terminus to ensure ER retention (4), calnexin has positively
charged cytosolic residues that do the same thing (3). Most ER
proteins act as molecular chaperones and participate in the
proper folding of polypeptides and their assembly into mulit-
subunit proteins. Calnexin together with calreticulin, plays a
key role in glycoprotein folding and its control within the ER,
by interacting with folding intermediates via t