gerhard steiner gsteiner at Mon Aug 28 06:14:57 EST 1995  In
article <01HUHHX4FA2C00AWKF at>, you say: >The best estimate of
the intrinsic Ts/Tv rate is probably that >determined by
comparison of the most closely related sequences >you have.   Is
there any experimental support for this? References?  >The more
distant the sequences, the more this rate >is randomized.  In my
dataset of molluscan 18S sequences, TS/TV ratios vary from 0.9
to 3.5.  The high values in the closely related species, but
average of 1.4.  High TS/TV ratios add a lot of standard
error/variation to branches, bootstraps  values correspondingly
decrease. So, is it really the best option to take the TS/TV
ratio of the most closely  related species?  Gerhard Steiner
More information about the Mol-evol mailing list