Research Article     • Jordan D. Ward equal contributor,
equal contributor Contributed equally to this work with: Jordan
D. Ward, Nagagireesh Bojanala     • Nagagireesh Bojanala equal
contributor,       Affiliations: Institute of Parasitology,
Biology Centre ASCR, Ceske Budejovice, Czech Republic,
University of South Bohemia, Ceske Budejovice, Czech Republic
• Teresita Bernal,     • Kaveh Ashrafi,      Affiliation:
Department of Physiology, University of California San
Francisco, San Francisco, California, United States of America
• Masako Asahina mail, (MA); (KRY)      Affiliations: Department
of Cellular and Molecular Pharmacology, University of California
San Francisco, San Francisco, California, United States of
America, Institute of Parasitology, Biology Centre ASCR, Ceske
Budejovice, Czech Republic, University of South Bohemia, Ceske
Budejovice, Czech Republic    • Keith R. Yamamoto mail (MA);
(KRY)     • Published: December 12, 2013   • DOI:
10.1371/journal.pgen.1003992    Author Summary