    1. T S Temelkova-Kurktschiev,   2. C Koehler,   3. E Henkel,
4. W Leonhardt,   5. K Fuecker and   6. M Hanefeld   1.
Institute for Clinical Metabolic Research, Technical Univeristy
Dresden, Germany.       OBJECTIVE: To observe the relationship
of fasting plasma glucose (FPG), postchallenge plasma glucose
(PG) (30, 60, 90, and 120 min during an oral glucose tolerance
test [OGTT], as well as maximal PG during an OGTT, postchallenge
glucose spikes [PGS], and glucose under the OGTT curve), and
HbA1c to intima-media thickness (IMT) as a marker of
atherosclerosis. RESEARCH DESIGN AND METHODS: OGTT, ultrasound
measurement of carotid IMT, and various atherosclerosis risk
factors, such as family history of diabetes, obesity, and/or
hyperlipoproteinemia, but without known diabetes, were analyzed
in 582 individuals aged 40-70 years and at risk for type 2
diabetes. RESULTS: In univariate analysis, all examined glycemic
parameters were significantly correlated to IMT. The 2-h
postchallenge plasma glucose showed the