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The MERIT Award  Page Options    • Print This Page   • Email
This Document  Popular Resources  MERIT Award Recipient: Michael
Caligiuri, M.D.  Michael Caligiuri, M.D. Sponsoring NCI
Division:  Division of Cancer Biology (DCB) Grant
Number:R37CA068458 Award Approved:September 2010
Institution:Ohio State University Department:Comprehensive
Cancer Center The Caligiuri Lab Literature Search in PubMed
IL-15 Characterization Through Experimental Immunology  Natural
killer (NK) cells are large granular lymphocytes that constitute
~10% of total peripheral blood lymphocytes in humans. NK cells
are part of the body's innate immune system providing the first
line of defense against invading pathogens and likely against
certain types of cancer. The recent discovery, in both
experimental and several clinical studies, of NK cells' ability
to recognize and control the relapse of chemo-resistant acute
myeloid leukemia (AML) could significantly improve the clini