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for luminescence  Sign up for newsletter  Chemiluminescence
Measurement of the Generation of Reactive Oxygen Species
Request more infoBernd Hipler, BMG LABTECH GmbH, Germany Uta-
Christina Hipler, Department of Dermatology, FSU Jena, Germany
• Very low ROS concentrations detectable   • Chemiluminescence
signals in candida species at c>108 blastospores / mL   • Linear
correlation between ROS and blastospores concentration  Click
here for PDF version of this application note.  Phagocytosis is
one of the oxygen depending processes in organisms. During the
unspecific immunological defense, the activity of
pentosephosphate cyclus is dramatically increased forming NADPH.
NADPH is needed to reduce the oxygen which is bonded to
membrane-based cytochromes. Therefore, the oxygen demand is
strongly increased (respiratory burst). During this process,
oxygen is converted into superoxide anions