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search Egl-9 family hypoxia-inducible factor 1 Protein EGLN1 PDB
2g19.png PDB rendering based on 2g19. Available structures PDB
Ortholog search: PDBe, RCSB Symbols EGLN1 ; C1orf12; ECYT3; HIF-
PH2; HIFPH2; HPH-2; HPH2; PHD2; SM20; ZMYND6 External IDs
OMIM606425 HomoloGene56936 ChEMBL: 5697 GeneCards: EGLN1 Gene EC
number RNA expression pattern PBB GE EGLN1 221497 x at tn.png
More reference expression data Species Human Mouse Entrez 54583
112405 Ensembl ENSG00000135766 ENSMUSG00000031987 UniProt Q9GZT9
Q91YE3 RefSeq (mRNA) NM_022051 NM_053207 RefSeq (protein)
NP_071334 NP_444437 Location (UCSC) Chr 1: 231.5 – 231.56 Mb Chr
8: 124.91 – 124.95 Mb PubMed search [1] [2]  Hypoxia-inducible
factor prolyl hydroxylase 2 (HIF-PH2), or prolyl hydroxylase
domain-containing protein 2 (PHD2), is an enzyme encoded by the
EGLN1 gene. It is also known as Egl nine homolog 1.[1][2][3][4]
The hypoxia response[edit]  HIF-1α is a ubiquitous,
constitutively synthesized tran