본문 바로가기   홈 > BT동향 > 기술동향  글 읽기 Proteomics Technology for Plasma
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3488 자료발간일 2006-05-23 등록일 2006-05-23 평점 평점이 없습니다.   Proteomics
Technology for Plasma & Serum   Detecting Low-Abundance
Biomarkers without Immunoaffinity Depletion of Abundant Proteins
Yuqiao Shen, Ph.D., Li Li, Ph.D., Jian Liao, Ph.D.   Fig.1:
Immunoaffinity depletion of the high-abundance proteins removes
many potentially important marker proteins. In addition to the
12 proteins that are designed to bind to the column, a large
number of low-abundance proteins are also bound to the column
Blood is a rich and readily accessible source for the detection
of diagnostic markers and therapeutic targets in many human
diseases, such as cardiovascular diseases, neurological
disorders, and cancer. Currently, however, only a handful of
plasma proteins are routinely used in the clinic for diagnostic
purposes. This is largely due to the lack of an effective
technology platform that rapidly d