Open Access Open Badges Nano Express  Biocompatibility of
hydrophilic silica-coated CdTe quantum dots and magnetic
nanoparticles   Author affiliations   For all author emails,
please log on.  Citation and License   Published: 6 April 2011
Fluorescent magnetic nanoparticles exhibit great application
prospects in biomedical engineering. Herein, we reported the
effects of hydrophilic silica-coated CdTe quantum dots and
magnetic nanoparticles (FMNPs) on human embryonic kidney 293
(HEK293) cells and mice with the aim of investigating their
biocompatibility. FMNPs with 150 nm in diameter were prepared,
and characterized by high-resolution transmission electron
microscopy and photoluminescence (PL) spectra and magnetometer.
HEK293 cells were cultured with different doses of FMNPs (20,
50, and 100μ g/ml) for 1-4 days. Cell viability and adhesion
ability were analyzed by CCK8 method and Western blotting. 30
mice were randomly divided into three groups, and were,
respectively, injected via tail vein with 20, 60, and