IGEM:Imperial/2010/Fast Response module/Activation
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Overview of the activation module  Image:Activation module.jpg
Quorum Sensing in B.substilis  The idea is to fuse our split
protease on the components of the quorum sensing system of
B.substilis. The signal peptide is the product of ComX gene. The
sensor is the transmembrane receptor ComP which
autophosphorylates(the first half of the split protease will be
attached on ComP). ComA is the relay compoment which gets
phosphorylated by ComP (the second part of the split protease
will be attached on the ComA). When ComP and Coma associate that
would produce the active protease.    • Chris D Hirst 12:12, 15
July 2010 (EDT): What causes expression of ComX under normal
circumstances in the cell?  Cracking the split Protease
(20/07/2010-N.K.)  Based on the review: "Monitoring regulated
protein-protein interactions using split TEV", I recognised the
following points to be taken into consideration in late