Structural Biochemistry/Proteins/Signaling Control of Splicing
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Technology advances in sequencing and microarrays allow for us
to better understand pre-mRNA splicing patterns in different
cells. For example, cellular splicing changes when it is
stimulated by factors such as DNA damage, neuron depolarization
and or metabolic changes in cells. In the last few years, there
have been more studies regarding patterns in mechanisms that
relate cellular stimuli to downstream alternative splicing
control. Some of these splicing events include degradation of
splicing factors, altered nuclear translocation, and regulated
synthesis of splicing factors.  What is alternative splicing and
how does it work?[edit]  Splicing overview  Alternative splicing
is a process that occurs during gene expression and allows for
the production of multiple proteins (protein isoforms) from a
single gene coding. Alternati