Integrative System Biology of iPSC-induced Neurons for
Identifying Novel Drug Targets   Pati, Soumya  Maletic-Savatic,
Mirjana  Baylor College of Medicine   2 years  Meixner
Translational Postdoctoral Fellowship    United States
State/Province Full:  United States  Autism is quickly emerging
as one of the most prevalent developmental diseases of our time.
Despite the large amount of scientific discoveries regarding the
etiology, pathology, and clinical assessments of this complex,
heterogeneous disorder, diagnostic and therapeutic biomarkers
that could enable early diagnosis and therapy are lacking.
Identification of clinically relevant biomarkers in brain tissue
is clearly rendered more difficult by the unavailability of the
tissue, the complexity and heterogeneity of the brain, and the
fact that peripheral tissues such as blood, urine and even
cerebrospinal fluid might not reflect brain pathology. This
research laboratory is experiences in the systems biology
approach to neurodevelopmental diseases and au