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ManuscriptEmail AlertsAbout JPNJournal of Psychiatry and
Neuroscience J Psychiatry Neurosci. Nov 2007; 32(6): 394–399.
PMCID: PMC2077351 How to increase serotonin in the human brain
without drugs Simon N. Young Editor-in-chief, Journal of
Psychiatry and Neuroscience, and Department of Psychiatry,
McGill University, Montréal, Que. Medical subject headings:
serotonin, exercise, phototherapy, food, depression, happiness
For the last 4 decades, the question of how to manipulate the
serotonergic system with drugs has been an important area of
research in biological psychiatry, and this research has led to
advances in the treatment of depression. Research on the
association between various polymorphisms and depression
supports the idea that serotonin plays a role, not only in the
treatment of depression but also in susceptibility to depression
and suicide. The research focus here has been on polymorphisms
of the serotonin transporter, but other serotonin-related ge