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Intestinal Peptide (VIP)  Anti -Vasoactive Intestinal Peptide
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Clone Host Grade Applications Polyclonal Rabbit Serum E IH
Vasoactive intestinal peptide (VIP) is a 28 amino acid peptide
(human, chr 6q26-q27). It is expressed and secreted by neurons
innervating primary and secondary immune organs such as lymph
nodes with a MW of 20kD. VIP is a potent neurotrophic factor
causes vasodilation, lowers arterial blood pressure, and relaxes
the smooth muscle of trachea, stomach and gall bladder. VIP also
modulates several T-lymphocyte activities including motility,
cytokine production, proliferation and apoptosis, VIP exerts its
biological activity by binding to two closely related class II
G-protein-coupled receptors VPAC-1 and VPAC-2 beside this VIP
has its own receptors VIP