SGD Paper Help  Garcia-Martinez J, et al.  (2012) The relative
importance of transcription rate, cryptic transcription and mRNA
stability on shaping stress responses in yeast. Transcription
3(1):39-44  Abstract: It has been recently stated that stress-
responding genes in yeast are enriched in cryptic transcripts
and that this is the cause of the differences observed between
mRNA amount and RNA polymerase occupancy profiles. Other studies
have shown that such differences are mainly due to modulation of
mRNA stabilities. Here we analyze the relationship between the
presence of cryptic transcripts in genes and their stress
response profiles. Despite some of the stress-responding gene
groups being indeed enriched in specific classes of cryptic
transcripts, we found no statistically significant evidence that
cryptic transcription is responsible for the differences
observed between mRNA and transcription rate profiles.  Status:
Published Type: Journal Article PubMed ID: 22456320  Topics
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