Fibroblast Growth Factor 21 (FGF21) in Human Cerebrospinal Fluid
Relationship With Plasma FGF21 and Body Adiposity    1. Harpal
S. Randeva1   1. 1Endocrinology and Metabolism Group, Clinical
Sciences Research Institute, Warwick Medical School, University
of Warwick, Coventry, U.K.   2. 2Department of Reproductive
Medicine and Surgery, Addenbrooke’s Hospital, Cambridge
University Hospitals National Health Service Foundation Trust,
Cambridge, U.K.   3. 3Department of Neuroendocrinology,
University of Lübeck, Lübeck, Germany   4. 41st Medical
Department, University of Lübeck Medical School, Lübeck, Germany
1. Corresponding author: Bee K. Tan, b.k.tan.1{at}   OBJECTIVE
Reports of increased circulating fibroblast growth factor 21
(FGF21) levels in obesity indicate that FGF21 may be implicated
in body weight homeostasis. We sought to investigate the
existence of FGF21 in human cerebrospinal fluid (CSF) and, if
present, the relationship between CSF FGF21 with body adiposity
and metabolic parameters.  RESEARCH DES