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Mood Lighting: Penn Researchers Determine Role Of Serotonin In
Modulating Circadian Rhythm   mcith_050710171338.jpg Proposed
model for the effect of serotonin molecular signaling in
fruitfly clock cells. Serotonin binds to its receptor, d5-HT1B,
setting off a cascade of events within the cell that involves
the clock proteins SGG, TIM, PER, and CRY, and governs the fly's
circadian response to light. Alternations in the level of the
serotonin receptor affects molecular and behavioral responses of
the fly to light. (Credit: Amita Sehgal, University of
Pennsylvania School of Medicine and Cell Press)  (Click image to
enlarge)  July 11, 2005 Philadelphia, PA - Researchers at the
University of Pennsylvania School of Medicine have determined
how serotonin decreases the body's sensitivity to light and that
exposure to constant darkness leads to a decrease in serotonin
levels in the brain of fruit flies. These findings suggest that
serotonin may play a ro