instruction: hi doctor my current medications are 60 my cymbalta for depression and 300 my seroquel for the sleep disorder I am in my 40s and I have had a few episodes of depression during my lifetime I was lucky enough to be able to attend a psychiatrist in a country I lived in for a long time it was a great help my question at the moment is about medication when I was quite depressed I took cymbalta and another antidepressant which I am fairly certain was wellbutrin I dropped the secondary antidepressant after a year or so as I began to feel better I am just considering using it again as I am now in a state of emotional upheaval due to a family death I have just got in touch with a go for an appointment in the next two weeks what I would like to know is it safe to take cymbalta seroquel and go back to wellbutrin how would I work the dosage would I start with 150 my of wellbutrin and possibly go up to 300 my when should I take the antidepressants can I take them both at the same time or do I need to space them out I am not prone to seizures and I have never had one I am a female
output: hi thank you for taking help from a psychiatrist you can take cymbalta and seroquel you are already on both medications so you should continue both medications if you fill depressed then take tablet wellbutrin 150 my once in the morning for a short period of time then we can taper off within months if you do not improve your depression on 150 my of dose after 15 days then we can increase the dosage as per requirement you can take medications together and you do not need to space out but you must take seroquel at night as it causes sedation even you should follow some non pharmacological management as mentioned below do exercises daily for 30 45 minutes like walking do meditation for 20 minutes daily eat healthy home cooked foods avoid junk foods spend quality time with friends and family daily spend time for creative hobbies like read good books write journals painting drawings learn new skills or language or musical instruments take enough 8 hours sleep daily avoid tobacco or alcohol or any substance abuse I hope this helps