instruction: hello doctor I understand that a high vacuolated neutrophil result can be indicative of impending sepsis is it possible for someone to have this result and an infection that does not make the patient symptoms visibly worse for a week if so could you give some examples of such infections the patient is not on antibiotics can a high vacuolated neutrophil result indicate some sort of problem other than an infection
output: hi I appreciate your knowledge you are right vacuolated neutrophils suggest towards invective etiology more likely but let me know you in such a case usually neutrophilia is also seen so vacuolated neutrophils interpretation should be done in accordance with total abc white blood corpuscles and total neutrophils count your clinical correlation and physical examination are also necessary vacuolations in neutrophils suggest phagocytic function of it in infection g pneumonia fungal infection septicemia typhoid etc sometime in inflammation also such cells are seen as you have rapid weight loss cause for that should be searched some of the causes are hiv acute infection cold gastrointestinal problems like celiac disease and inflammatory bowel disease hyperthyearoidism diabetes tuberculosis etc so the clinical correlation is necessary to do further work up provide your other reports if it has been done along with full abc complete blood count report I hope this helps