instruction: hello doctor I am 18 years old the medication I take is bupropion al 150 my I have not wetted the bed since I was years old because I used to have problems then for some reason these past few days I have been wetting the bed again I am not sure what is going on
output: hi welcome to icliniq com I am sorry to hear about your nocturnal enuresis involuntary urination at night whilst sleeping rest assured it is according to evidence most likely not due to a serious cause and should be fleeting bupropion is known to rarely cause bedwetting as a side effect especially in the first six months bupropion works therapeutically with your body neurotransmitters chemicals used for signaling and sending of specific nervous system messages and can sometimes cause some of the minor nervous system signals to get confused for a short period making your bladder muscle contract and urethra relax for example causing bedwetting this rare bupropion side effect do go away within four to six weeks in most patients without specific treatment the following is what you could do apply a few general measures to decrease the risk of nocturnal enuresis like not having any fluids two to three hours before bedtime avoiding any caffeinated drinks after 0 am take your bupropion in the morning relax and take your time to empty your bladder completely at bedtime take any other supplements and vitamins in the morning make sure your room is properly darkened with no luminescent clock faces insight quiet room with soothing monotone white noise for example the sound of an air conditioner in the background do not think or worry about whether you might wet the bed it is a silly transient medication side effect which is out of your control for now if you are sleeping well at the moment without having much trouble falling asleep again some evidence does suggest benefit from setting a relatively soft alarm for mid sleep as I mentioned before this particular bupropion side effect should resolve by itself within four to six weeks typically if however it does not one can consider changing a second line treatment or adding one of the tablets we usually use to treat primary nocturnal enuresis this is rarely necessary however and there is a high probability that your problem will resolve within a short period of time