instruction: hello doctor I have had some muscular soreness for about one and a half years I have no other symptoms normal hematology abc bloodwork always comes out fine the only thing in the last bloodwork is I had ana positive with 160 homogenous and the dna is abs came out as which said it was positive as well ear creatinine c3 ca all come out normal can you help shed some light on this I have been googling and it says I could have an auto immune disease if so which ones are likely with this bloodwork I am currently on nexium xanax and proair when needed
output: hi you have mildly positive antinuclear antibody titer which suggests auto immune disease and anti didna double stranded dna which is slightly above the normal range suggests that you might have she systemic lupus erythematosus but there are other criteria out of which four should be positive to confirm she people who have positive ana or anti is dna but cannot fulfill the clinical criteria for she need to be followed closely because they are at risk to develop she in the future she is a chronic autoimmune disease that can affect almost any organ system muscular manifestation includes myalgias as in your case titers of anti didna antibodies often fluctuate with disease activity and are therefore useful in many patients for following the course of she I would suggest you to consult a rheumatologist you need to take drugs that suppress your immunity steroids are the treatment of choice I would advise repeat testing for both ana and anti didna after one or two months to look for any change in the titer rising titers or very high titers of egg anti didna antibodies are closely associated with impending or already flared she genetic anti didna and ana titer collagen vascular disease she steroids