In the Fantastic Five series set in the MC2, Doom is revealed to be held captive by the Sub-Mariner for ten years, after the destruction of Atlantis. Doom manages to escape, and uses the same device he once employed to imbue Terrax with the Power Cosmic on his Doombots- unable to use it on himself as his human body would be destroyed from the strain-, and attempts to take over the world. Taking advantage of Doom's desire to prove himself superior, Reed Richards challenges Doom to a psychic duel, using a device that will send the loser's mind to the Crossroads of Infinity. The two are so evenly matched that both are sent to the Crossroads - although Namor notes that it is possible that Reed sacrificed himself to try to save Doom - leaving their bodies as empty shells, although Reed's teammates note that there is always a possibility that the two shall return so long as their bodies remain alive.