Multiparameter analysis of Rb/ Xe SEOP at high xenon pressure and photon flux could be used as 3D-printing and stopped flow contrasting agent in clinical scale. In situ technique, the NMR machine was run for tracking the dynamics of Xe polarization as a function of SEOP-cell conditioning with different operating parameters such as data collecting temperature, photon flux, and Xe partial pressure to enhance the Xe polarization (P Xe).