In January 2018, Mack became an assistant professor in the Department of Physics at North Carolina State University and a member of the university's Leadership in Public Science Cluster. She joined the Perimeter Institute for Theoretical Physics in June 2022 as the inaugural Hawking Chair in Cosmology and Science Communication. The Canadian multidisciplinary research organization CIFAR named her one of the CIFAR Azrieli Global Scholars in 2022.