She studied physics at the Pierre and Marie Curie University and completed a PhD in molecular spectroscopy in 1973. She began her career as a researcher at Inserm, where she was involved in the development of the first digital scanner in nuclear medicine. She then joined the Frédéric-Joliot hospital department of the French Alternative Energies and Atomic Energy Commission where she developed Positron emission tomography locally as part of a second thesis in biophysics completed in 1984 at the University of Paris-Sud under the direction of Nobel Prize winner Georges Charpak. She became associate professor in Physics and Medical Biophysics at the Pierre and Marie Curie University and the University of Paris-Sud.