In more of an anti-hero role, the Earth-2149 version of Doom is still ruler of Latveria. Doom has fortified his castle to defend against the infected superheroes and refuses help from Nick Fury, and takes in refugees for the purpose of repopulating the planet once the situation is resolved. To the disgust of his allies, it is revealed Doom has only chosen the hardiest breeding stock of the Latverian survivors; there are no elderly people or children. He creates a makeshift portal that will allow escape into other dimensions, should the zombie plague doom the planet. Doom is forced to vaporize the mutant Dazzler and the zombified Enchantress after the latter infects the former, but is then attacked by the zombified Marvel superheroes and infected by Reed Richards, who had infected himself and his teammates on purpose.