In 2021 L'Huillier was awarded the Optical Society of America Max Born Award for "pioneering work in ultrafast laser science and attosecond physics, realizing and understanding high harmonic generation and applying it to time-resolved imaging of electron motion in atoms and molecules". In 2022 she received the Wolf Prize in Physics for "pioneering contributions to ultrafast laser science and attosecond physics" jointly with Ferenc Krausz and Paul Corkum. Also for 2022, the three were awarded the BBVA Foundation Frontiers of Knowledge Award in Basic Sciences. She also received the French Legion of Honour the same year.