During the " Spider-Geddon " storyline, the Superior Octopus is seen fighting the Night Shift. The Superior Octopus agrees to spare them more pain in exchange for the Night Shift becoming his agents, where he will compensate them from his own funds. They agree to the terms and are ordered to return the stolen items. The Superior Octopus leaves, advising them never to cross him or they will not live long enough to regret it. After a day at Horizon University and saving some people on the Bay Bridge, the Superior Octopus fights Arnim Zola, a bio-duplicate of Gorgon, and some HYDRA agents who seek to repossess his services to rebuild HYDRA. The Superior Octopus states that he is done with his end of the bargain and attacks them. When the Gorgon bio-duplicate turns the Superior Octopus to stone and shatters him, another Superior Octopus body emerges, where it destroys the Gorgon bio-duplicate and defeats Arnim Zola, while informing him to spread the word to HYDRA to never come for him again. The Superior Octopus' inner monologue states that he had perfected Miles Warren 's cloning technology where each clone had to be made from the deceased to maintain their memories as a way to conquer death. However, after Octavius forces Count Nefaria into retreating from Los Angeles, he is confronted in his cloning workshop by the Spider-Army. They reveal that his cloning process has been 'hacked' by the Inheritors, who fed his computers hours-old data until they were ready to manifest, with these new Inheritors swiftly killing Spider-Man Noir and Spider-UK. Octavius then quotes "What have I done ..." After initiating his base's self-destruct sequence to slow down the Inheritors, the Superior Octopus states that they still should have killed the Inheritors while they had the chance. Upon heading to his lab at Horizon High to change into his Superior Spider-Man appearance, he goes to recruit Kaine and states that they should leave Ben Reilly out of the fight, since Jennix is targeting the cloning technology from the now-defunct New U Technologies. As the Superior Spider-Man and Kaine enter the portal, they are unaware that Ben Reilly has followed them. The Superior Spider-Man heads to Earth-1048 to recruit that world's Spider-Man, where he helps to defeat the Tarantula and learned about his counterpart. After Spider-Norman and Spiders-Man sundered Earth-616's connection to the Web of Life and Destiny, Octavius seemingly betrayed Ben, giving him to the Inheritors in exchange for the other Spiders being left alone. When Spider-Man of Earth-1048, who had been secretly following both Octavius and Ben from behind, believed Octavius made the same mistake as his counterpart in betraying their own, Octavius revealed to him that he and Ben purposely planned this to trick the Inheritors into consuming the clone that will drove them insane, starting from when he was forced to relive the memories of Ben's 29 deaths and resurrections. With the help from surviving Spider-Men who are trapped in Earth-616, including those who were trapped in another universe (including Kaine and 616's Peter), Octavius manages to resurrect Ben in his 30th resurrection. With the Inheritors turned into babies to be raised by Spider-Ma'am (Aunt May) for their redemption; the same goes for Morlun, who is currently in 616's high-security prison. Octavius resumes being the Superior Spider-Man.