This leads to the second question. Divergent or not, finite or infinite, is the zero-point energy of any physical significance? The ignoring of the whole zero-point energy is often encouraged for all practical calculations. The reason for this is that energies are not typically defined by an arbitrary data point, but rather changes in data points, so adding or subtracting a constant (even if infinite) should be allowed. However this is not the whole story, in reality energy is not so arbitrarily defined: in general relativity the seat of the curvature of spacetime is the energy content and there the absolute amount of energy has real physical meaning. There is no such thing as an arbitrary additive constant with density of field energy. Energy density curves space, and an increase in energy density produces an increase of curvature. Furthermore, the zero-point energy density has other physical consequences e.g. the Casimir effect, contribution to the Lamb shift, or anomalous magnetic moment of the electron, it is clear it is not just a mathematical constant or artifact that can be cancelled out.