Pressure variation effects and corrections due to mixing are generally minimal unless a reaction involves non-ideal gases and/or solutes, or is carried out at extremely high pressures. The enthalpy of mixing for a solution of ideal gases is exactly zero; the same is true for a reaction where the reactants and products are pure, unmixed components. Contributions to reaction enthalpies due to concentration variations for solutes in solution generally must be experimentally determined on a case by case basis, but would be exactly zero for ideal solutions since no change in the solution's average intermolecular forces as a function of concentration is possible in an ideal solution.