Nergis Mavalvala (born 1968) is a Pakistani-American astrophysicist. She is the Curtis and Kathleen Marble Professor of Astrophysics at the Massachusetts Institute of Technology (MIT), where she is also the dean of the university's school of science. She was previously the Associate Head of the university's Department of Physics. Mavalvala is best known for her work on the detection of gravitational waves in the Laser Interferometer Gravitational-Wave Observatory (LIGO) project, and for the exploration and experimental demonstration of macroscopic quantum effects such as squeezing in optomechanics. She was awarded a MacArthur Fellowship in 2010.