The first heavy-ion collisions at modestly relativistic conditions were undertaken at the Lawrence Berkeley National Laboratory (LBNL, formerly LBL) at Berkeley, California, U.S.A., and at the Joint Institute for Nuclear Research (JINR) in Dubna, Moscow Oblast, USSR. At the LBL, a transport line was built to carry heavy ions from the heavy-ion accelerator HILAC to the Bevatron. The energy scale at the level of 1–2 GeV per nucleon attained initially yields compressed nuclear matter at few times normal nuclear density. The demonstration of the possibility of studying the properties of compressed and excited nuclear matter motivated research programs at much higher energies in accelerators available at BNL and CERN with relativist beams targeting laboratory fixed targets. The first collider experiments started in 1999 at RHIC, and LHC begun colliding heavy ions at one order of magnitude higher energy in 2010.