The Casimir effect shows that quantum field theory allows the energy density in certain regions of space to be negative relative to the ordinary matter vacuum energy, and it has been shown theoretically that quantum field theory allows states where energy can be arbitrarily negative at a given point. Many physicists, such as Stephen Hawking, Kip Thorne, and others, argued that such effects might make it possible to stabilize a traversable wormhole. The only known natural process that is theoretically predicted to form a wormhole in the context of general relativity and quantum mechanics was put forth by Juan Maldacena and Leonard Susskind in their ER = EPR conjecture. The quantum foam hypothesis is sometimes used to suggest that tiny wormholes might appear and disappear spontaneously at the Planck scale, and stable versions of such wormholes have been suggested as dark matter candidates. It has also been proposed that, if a tiny wormhole held open by a negative mass cosmic string had appeared around the time of the Big Bang, it could have been inflated to macroscopic size by cosmic inflation.