Octavius is introduced as a scientist at OsCorp and a corporate spy for Justin Hammer, Norman Osborn's business rival. He is caught in a lab accident involving the drug OZ that turned Norman into the Green Goblin. After the accident, his metal arms are grafted onto his body and he is able to communicate with them via telepathy. He seeks revenge against Hammer, but is defeated by Spider-Man, although Hammer died of a heart attack caused by Octavius' attack.