Mukhopadhyaya, who secured his PhD from the Rajabazar Science College campus of Calcutta University, has done reportedly notable work on neutrino mass and is known to have been successful in theorizing that gauge boson fusion as the dominant mode of supersymmetric particle production. He has delivered invited lectures at a number of conferences and was a member of the national organizing committees of the International Conference on particles, Strings and Cosmology (PASCOS), held in Mumbai in 2003 as well as the XXI DAE-BRNS High Energy Physics Symposium held in 2014. His studies have been documented by way of a number of articles and ResearchGate , an online article repository of scientific articles, has listed 184 of them. He has also edited one book, Physics at the Large Hadron Collider, along with Amitava Datta and Amitava Raychaudhuri and has contributed chapters to books edited by others.