Bethe attended the Goethe-Gymnasium in Frankfurt, Germany. His education was interrupted in 1916, when he contracted tuberculosis, and he was sent to Bad Kreuznach to recuperate. By 1917, he had recovered sufficiently to attend the local Realschule and the following year, he was sent to the Odenwaldschule, a private, coeducational boarding school. He attended the Goethe-Gymnasium again for his final three years of secondary schooling, from 1922 to 1924.