As in the comics, Thawne is depicted as a scientist-turned- metahuman criminal speedster from the future and the archenemy of Barry Allen / The Flash. He originally idolized the Flash and replicated the accident that gave him his powers, but became obsessed with ruining his life upon learning that he was destined to become his greatest enemy–the Reverse-Flash. After traveling back in time, Thawne inadvertently strands himself in the 21st century and is forced to orchestrate the Flash's creation to return to his own time period. Though he is defeated by the Flash, he returns to torment him numerous times, which has brought him into conflict with other heroes including Green Arrow, Supergirl, and the Legends of Tomorrow.