The term Quantum Crystallography was first introduced in revisitation articles by L. Huang, L. Massa and Nobel Prize winner Jerome Karle, who associated it with two mainstreams: a) crystallographic information that enhances quantum mechanical calculations and b) quantum mechanical approaches to improve crystallography information. This definition mainly refers to studies started in the 1960s and 1970s, when first attempts to obtain wave functions from scattering experiments appeared, together with other methods to constrain a wavefunction to experimental observations like the dipole moment. This field has been recently reviewed, within the context of this definition.