Main-sequence stars employ two types of hydrogen fusion processes, and the rate of energy generation from each type depends on the temperature in the core region. Astronomers divide the main sequence into upper and lower parts, based on which of the two is the dominant fusion process. In the lower main sequence, energy is primarily generated as the result of the proton–proton chain, which directly fuses hydrogen together in a series of stages to produce helium. Stars in the upper main sequence have sufficiently high core temperatures to efficiently use the CNO cycle (see chart). This process uses atoms of carbon, nitrogen, and oxygen as intermediaries in the process of fusing hydrogen into helium.