During the " Dead No More: The Clone Conspiracy " storyline, Peter decides to have Parker Industries get familiar with New U Enterprises' "New U" system, which is a program where replacement organs are cloned for those suffering from serious injuries. Upon hearing about it from within the Living Brain, Doctor Octopus' consciousness expresses an interest in the procedure. When Peter Parker scanned the Living Brain to find out why it was acting unusually, Doctor Octopus' consciousness asked why it was erased. Realizing the truth, Peter Parker shut down the Living Brain, only for Doctor Octopus' consciousness to reactivate it and cause it to self-destruct while escaping in the Octobot. Arriving at New U Enterprises, the Doctor Octopus-possessed Octobot plans to get his biological body back, convinced that the consciousness in Parker's body was "infected" by its time in Spider-Man to believe that Peter was superior rather than himself. Upon heading to Potter's Field, the Doctor Octopus-possessed Octobot finds that Doctor Octopus' body was grave-robbed, alongside those of Alistair Alphonso Smythe and other villains. It traces the grave robbery to New U Technologies. Finding Doctor Octopus' body, the Doctor Octopus-possessed Octobot allowed it to be cloned and perfected. After eliminating the copy of Peter Parker's consciousness, Doctor Octopus gains control of the clone body and emerges from the vat where he resembles his earlier appearance. The Jackal was present where he presents him with his tentacle pack. Now an ally of Jackal, Doctor Octopus receives the special New U Pills to prevent his body from suffering clone degeneration.