The measure of the ionizing effect of gamma and X-rays in dry air is called the exposure, for which a legacy unit, the röntgen, was used from 1928. This has been replaced by kerma, now mainly used for instrument calibration purposes but not for received dose effect. The effect of gamma and other ionizing radiation on living tissue is more closely related to the amount of energy deposited in tissue rather than the ionisation of air, and replacement radiometric units and quantities for radiation protection have been defined and developed from 1953 onwards. These are: