While studying the clones of Kaine and Electro to perfect the Proto-Clone, Anna Maria was brought to Otto and she becomes uncomfortable when Doctor Octopus starts appealing towards his love interest. When Jackal enters the laboratory, Anna Maria reveals she knows how to stop the decaying process on the clones and Jackal offers her the "Proto-Clone" body in exchange for the formula. Octavius takes offense to Jackal's comments on Maria's dwarfism and attacks his boss. Then he pulls a switch which activates the Carrion Virus in all of the clones and causes them to start rapidly decaying.