Having finally been made into the notorious supervillain he hoped to be at the cost of his humanity, Macendale put his personal enmity for Spider-Man aside and used his demonic powers to be a top contract killer. He offered his mercenary services to Hammerhead and Tombstone to eliminate Robbie Robertson but is stopped by Spider-Man and Puma. Macendale next conspired with Carrion to eliminate Spider-Man before his co-conspirator ultimately nearly took both villains out instead. Macendale goes after Doctor Strange but an illusion spell is cast to try to calm the monstrous man/demon and Macendale sees his true face in reflections of himself. Macendale was later stiff-armed by Doctor Octopus into joining the Sinister Six 's second incarnation which twice tried to take over the world, failing due to counter measures by Spider-Man, Hulk, Ghost Rider, the Fantastic Four and many more heroes.