Radio waves are affected by the plasma properties of the ISM. The lowest frequency radio waves, below ≈ 0.1 MHz, cannot propagate through the ISM since they are below its plasma frequency. At higher frequencies, the plasma has a significant refractive index, decreasing with increasing frequency, and also dependent on the density of free electrons. Random variations in the electron density cause interstellar scintillation, which broadens the apparent size of distant radio sources seen through the ISM, with the broadening decreasing with frequency squared. The variation of refractive index with frequency causes the arrival times of pulses from pulsars and Fast radio bursts to be delayed at lower frequencies (dispersion). The amount of delay is proportional to the column density of free electrons (Dispersion measure, DM), which is useful for both mapping the distribution of ionized gas in the Galaxy and estimating distances to pulsars (more distant ones have larger DM).