Doctor Octopus (Dr. Otto Octavius), also known as Doc Ock for short, is a fictional character appearing in American comic books published by Marvel Comics. The character was created by Stan Lee and Steve Ditko and first appeared in The Amazing Spider-Man #3 (July 1963). He is a highly intelligent, myopic, and stocky mad scientist who sports four strong and durable appendages resembling an octopus 's tentacles, which extend from his body and can be used for various purposes. After his mechanical harness became permanently fused to his body during a lab accident, he turned to a life of crime, and came into conflict with the superhero Spider-Man. He has endured as one of Spider-Man's most prominent villains, and is regarded as one of his three archenemies, alongside the Green Goblin and Venom. He is the founder and leader of the Sinister Six, the first supervillain team to oppose Spider-Man.