While quantum effects are significant in the physiology of the brain, critics of quantum mind hypotheses challenge whether the effects of known or speculated quantum phenomena in biology scale up to have significance in neuronal computation, much less the emergence of consciousness as phenomenon. Daniel Dennett said, "Quantum effects are there in your car, your watch, and your computer. But most things—most macroscopic objects—are, as it were, oblivious to quantum effects. They don't amplify them; they don't hinge on them."