In geometric topology, the theory of manifolds is characterized by the way dimensions 1 and 2 are relatively elementary, the high-dimensional cases n > 4 are simplified by having extra space in which to "work"; and the cases n = 3 and 4 are in some senses the most difficult. This state of affairs was highly marked in the various cases of the Poincaré conjecture, in which four different proof methods are applied.