String theory represents an outgrowth of S-matrix theory, a research program begun by Werner Heisenberg in 1943 following John Archibald Wheeler 's 1937 introduction of the S-matrix. Many prominent theorists picked up and advocated S-matrix theory, starting in the late 1950s and throughout the 1960s. The field became marginalized and discarded in the mid-1970s and disappeared in the 1980s. Physicists neglected it because some of its mathematical methods were alien, and because quantum chromodynamics supplanted it as an experimentally better-qualified approach to the strong interactions.