Amy Farrah Fowler, PhD (portrayed by Mayim Bialik ; main The Big Bang Theory : seasons 4–12; guest: The Big Bang Theory season 3, Young Sheldon season 4, 7) is a neuroscientist with a research focus on addiction in primates and invertebrates, occasionally mentioning such experiments involving addiction. (Bialik herself has a PhD in neuroscience.) She is Sheldon's love interest in the series, and they marry at the end of season 11. They are revealed to have children in Young Sheldon.