While the film is heavily fictionalized for dramatic purposes, the plot managed to adhere to the facts more than most biopics of the 1930s and 1940s. Madame Curie completely omits any mention of Marie's family in Paris, including her sister Bronisława, an obstetrician, with whom she was very close. There is also virtually no mention of Marie's intense devotion to politics and the liberation/independence of her native Poland.