Otto Octavius appears in Insomniac Games ' Marvel's Spider-Man series, voiced by William Salyers. Once a close friend of Norman Osborn and co-founder of Oscorp, this version left the company due to its unethical genetic experiments. Founding his own company, Octavius Industries, he worked to perfect prosthetic limb technology, motivated by a neurological disorder he was developing. Octavius later employed Peter Parker, whom he mentored, as his lab assistant and eventually became aware of his activities as Spider-Man, but chose to hide this from him.