Quantum Monte Carlo, and more specifically diffusion Monte Carlo methods can also be interpreted as a mean-field particle Monte Carlo approximation of Feynman – Kac path integrals. The origins of Quantum Monte Carlo methods are often attributed to Enrico Fermi and Robert Richtmyer who developed in 1948 a mean-field particle interpretation of neutron-chain reactions, but the first heuristic-like and genetic type particle algorithm (a.k.a. Resampled or Reconfiguration Monte Carlo methods) for estimating ground state energies of quantum systems (in reduced matrix models) is due to Jack H. Hetherington in 1984. In molecular chemistry, the use of genetic heuristic-like particle methodologies (a.k.a. pruning and enrichment strategies) can be traced back to 1955 with the seminal work of Marshall N. Rosenbluth and Arianna W. Rosenbluth.