Ghosh is a researcher, teacher, orator and an academic administrator. Ghosh has B.Sc.(Physics honors) and M.Sc.(Physics) degrees from the University of Calcutta campus - Rajabazar Science College, and a Ph.D. in Physics from the University of Rochester, NY in Quantum Optics where she worked as a Rush Rhees Fellow. Her research interests are in Experimental and Theoretical Quantum Optics, Laser Physics, Nonlinear Optics, and Quantum Information. Her work with Prof Leonard Mandel on two-photon interference (using the nonlinear optical process of spontaneous parametric down-conversion) involved the creation and use of a source of entangled photon pairs, and of single photons. After her Ph.D., she returned to India and joined the School of Physical Sciences, Jawaharlal Nehru University, where she held academic and administrative positions over a span of 24 years. She has also held several Visiting Positions at Université Paris-Sud, Universite de Rennes I and École Normale Supérieure among others.