Column separation is a phenomenon that can occur during a water-hammer event. If the pressure in a pipeline drops below the vapor pressure of the liquid, cavitation will occur (some of the liquid vaporizes, forming a bubble in the pipeline, keeping the pressure close to the vapor pressure). This is most likely to occur at specific locations such as closed ends, high points or knees (changes in pipe slope). When subcooled liquid flows into the space previously occupied by vapor the area of contact between the vapor and the liquid increases. This causes the vapor to condense into the liquid reducing the pressure in the vapor space. The liquid on either side of the vapor space is then accelerated into this space by the pressure difference. The collision of the two columns of liquid (or of one liquid column if at a closed end) causes a large and nearly instantaneous rise in pressure. This pressure rise can damage hydraulic machinery, individual pipes and supporting structures. Many repetitions of cavity formation and collapse may occur in a single water-hammer event.