After his defeat by Tyger Wylde, Doom underwent special surgery: nanotechnology was neurocybernetically added to the nervous system, speeding up those motor responses, allowing him to interface directly with any technology and heal himself from serious injuries. Due to his fragmented memory, Doom's mystical abilities were drastically decreased. Therefore, Doom had to rely on Vox for his natural talents. With his memory restored, he has full access to them again. He possesses extensive knowledge of all sciences, as well as is an expert in robotics, trans-Einsteinian physics, genetic engineering, military technology, chronophysics, biochemistry, and other fields.