Octavius makes a brief appearance, confronting Osborn as the latter breaks out of the Triskelion; he attacks his former boss to prevent his escape, informing him that he betrayed him by giving the OZ formula to the FBI. Octavius beats Osborn senseless until his other former ally Electro intervenes and knocks him out. During the Ultimate Mystery, Octavius appears as a member of Roxxon 's Brain Trust.