With a “farewell” towards the old images of substance and its replacement by “relatedness” and “connectivity”, the borders between power of interpretations in-between natural sciences and humanities / cultural sciences are getting blurred. The theoretical fundamentals of verification and falsification of “reality” are - severely taken - dissolving. Also and particularly the fundamentals of our social, cultural, economical and political sciences and their traditions are put basically into question, since they constructed complex, but nevertheless deterministically closed theorems in their course of emancipation to the “hard” natural sciences.