When it comes to the Multiversal Masters of Evil conquering another Earth before they can revisit Earth-616, they are attacked by Ghost Rider. After Ghost Rider subdues Black Skull, King Killmonger, and Ghost Goblin, Doom Supreme fights Ghost Rider and starts to overpower him. Ant-Man of Earth-818 and the Deathlok that Ghost Rider has been traveling with arrive where the former shrinks Doom Supreme. When Dark Phoenix attacks, Deathlok buys Ant-Man of Earth-818 time to get Ghost Rider away. While stating that the Multiversal Masters of Evil must regroup and he must get back to his normal size, Doom Supreme that that he knows where they are going and that they will visit that location to do one more slaughter. Doom Supreme vows that "No Avenger gets out alive".