Chiral magnetic effect (CME) is the generation of electric current along an external magnetic field induced by chirality imbalance. Fermions are said to be chiral if they keep a definite projection of spin quantum number on momentum. The CME is a macroscopic quantum phenomenon present in systems with charged chiral fermions, such as the quark–gluon plasma, or Dirac and Weyl semimetals. The CME is a consequence of chiral anomaly in quantum field theory ; unlike conventional superconductivity or superfluidity, it does not require a spontaneous symmetry breaking. The chiral magnetic current is non-dissipative, because it is topologically protected: the imbalance between the densities of left-handed and right-handed chiral fermions is linked to the topology of fields in gauge theory by the Atiyah-Singer index theorem.