He then worked as a researcher at the University of California - Santa Barbara in the United States and the Université de Paris VII in France. He became a fellow at CERN in Geneva in 2005. In October 2011, Hertog was appointed professor at the Institute for Theoretical Physics at KU Leuven through the Odysseus program of the Flemish government. He leads a research group studying the relationship between the Big Bang and string theory, with the idea that concepts like space and time lose their meaning. He also emphasizes Georges Lemaître 's insight that the Big Bang is central to Einstein's gravitational waves. Hertog worked in the field of quantum cosmology and string theory with James Hartle and Stephen Hawking. In 2011, after years of research, they came to a new insight by combining the mathematics of quantum cosmology and that of string theory. In 2018, he published 'A smooth exit from eternal inflation?' with Stephen Hawking.