After graduating, Alpert worked at PBS as a researcher and producer on documentary series covering historical and scientific topics. She then joined the Museum of Science in 1999, where she began to explore the use of YouTube as a means to introduce science concepts to a broad audience. Alpert still creates short films relating to her work at the Museum of Science. Her work on developing the Current Science & Technology Center is covered in the 2004 book Creating Connections: Museums and the Public Understanding of Current Research.