This factor of 200 = ⁠ 20% / 0.1% ⁠ comes from two causes: The pion has a mass only about ~130 times the leptons, but the extra energy appears as different kinetic energies of the pion or leptons, and results in relatively more kinetic energy transferred to a heavier product pion, in order to conserve momentum. The much larger total energy losses from pion production result in pion production becoming the process limiting high-energy cosmic-ray travel, rather than the lower-energy process of light-lepton production.