Some GUT theories like SU(5) and SO(10) suffer from what is called the doublet-triplet problem. These theories predict that for each electroweak Higgs doublet, there is a corresponding colored Higgs triplet field with a very small mass (many orders of magnitude smaller than the GUT scale here). In theory, unifying quarks with leptons, the Higgs doublet would also be unified with a Higgs triplet. Such triplets have not been observed. They would also cause extremely rapid proton decay (far below current experimental limits) and prevent the gauge coupling strengths from running together in the renormalization group.