In the field of nuclear safety (as implemented at U.S. government-owned facilities) the margin of safety has been defined as a quantity that may not be reduced without review by the controlling government office. The U.S. Department of Energy publishes DOE G 424.1-1, "Implementation Guide for Use in Addressing Unreviewed Safety Question Requirements" as a guide for determining how to identify and determine whether a margin of safety will be reduced by a proposed change. The guide develops and applies the concept of a qualitative margin of safety that may not be explicit or quantifiable, yet can be evaluated conceptually to determine whether an increase or decrease will occur with a proposed change. This approach becomes important when examining designs with large or undefined (historical) margins and those that depend on "soft" controls such as programmatic limits or requirements. The commercial U.S. nuclear industry utilized a similar concept in evaluating planned changes until 2001, when 10 CFR 50.59 was revised to capture and apply the information available in facility-specific risk analyses and other quantitative risk management tools.