Jackson joined the Theoretical Physics Research Department at AT&T Bell Laboratories in 1976, examining the fundamental properties of various materials. She began her time at Bell Labs by studying materials to be used in the semiconductor industry. She worked in the Scattering and Low Energy Physics Research Department from 1978, and moved to the Solid State and Quantum Physics Research Department in 1988. At Bell Labs, Jackson researched the optical and electronic properties of two-dimensional and quasi-two-dimensional systems.