Minecraft wiki entry for Combat, associated text: If the player are the one that gets hit, and the damage is too much for the player to re-engage combat, the best option is to use a splash potion. Don't immediately use the potion, because the player might also heal the opponents. Instead, run out of the opponent's range, and, while running, look down briefly and throw the potion. If it is an instant health potion, turn around and surprise their opponent with a quick attack. If it is a regeneration potion, wait for their health to regenerate to full and turn around and lay as many hits on them as they can. The regeneration effect will be a huge advantage, allowing you to attack without fear of losing health too quickly.