Minecraft wiki entry for Combat, associated text: Overall though, an enchanted bow and good skill are the most effective ways to deal with a ghast. Shooting arrows can be difficult at longer ranges, meaning a bow enchanted with infinity helpful, letting the player shoot many arrows without losing any. Another great weapon is the crossbow with the Multishot enchantment as it fires 3 arrows at once in a different direction, giving a high chance that one of them hits the ghast. Arrows fired from crossbows has faster and further range than bows.