Minecraft wiki entry for Nether_survival, associated text: A player can crouch when near lava as a safeguard to avoid falling in. However, you still get knockback from being hit.
Mobs such as the ghast can surprise the player, so the player should be watchful of their environment, especially when in bad positions, such as bridging a gap.
A zombified piglin farm can be created by walling the player off, then killing the piglins through a small hole.
Killing magma cubes can help the player collect magma cream, which is used for brewing potion of fire resistance, an extremely useful potion in the Nether. One can also get Potion of fire resistance from piglin barter.
Avoid getting lost in the Nether's low visibility by placing markers, such as torches or jack o'lanterns. Any markings suffice, but make sure they are not native to the Nether.
The player should be careful on gravel, as gravel can generate with no supporting blocks, making it fall when it receives an update.
Glass and string block a ghast's vision, allowing the player to see ghast filled areas without being shot at. This is useful for bases in the Nether.
Bringing 10 obsidian and a flint and steel (or fire charge) allow the player to return to the Overworld if they become lost. Compasses don't work in the Nether, unless linked to a lodestone. A respawn anchor charged with glowstone in a base you've built avoids you having to find your way back entirely.
Bring a pumpkin or a jack o'lantern. They can help you find your direction, as the stem on the top of the pumpkin always faces Northwest even in the Nether, no matter what direction the Pumpkin itself is facing.
As long as there are no ghasts or blazes present, traversing the Nether by mining along the edge of a wall is fast, safe, and efficient, unlike tunneling through said wall, which requires a fast reaction time and/or the constant digging of pits for lava to drain to.
Wear a piece of golden armor (possibly enchanted) when traversing through the Nether to avoid piglin attacks.
Or place a soul fire based block to scare them away. Torches and campfires work, but only the soul kind.
Bring some warped fungus as a defense toward hoglins.
Know your biome: Knowing the threats of the biome you're in can be invaluable. In Nether Wastes, zombified piglins, piglins, and magma cubes roam, with the occasional ghast or enderman. In Crimson Forests, Piglins, Hoglins, and Zombified Piglins roam. In a warped forest, only endermen spawn. In Soul Sand Valleys, ghasts are abundant, along with skeletons and the occasional enderman. In basalt deltas, Magma Cubes spawn abundantly, along with some ghasts. The lava oceans are home to the striders.