microtubule organization of spindle fibers DNA synthesis of spindle protein membrane transport of spindle fibers RNA synthesis of spindle protein
At concentrations of 0.1-1 µg/ml colchicine, a natural plant product, can cause the mitotic arrest of dividing cells at metaphase through disrupting the spindle apparatus. Colchicine interferes with which of these cell functions during cell division?

Options:
- microtubule organization of spindle fibers
- DNA synthesis of spindle protein
- membrane transport of spindle fibers
- RNA synthesis of spindle protein

microtubule organization of spindle fibers