Read the following passage and answer if the question is true or false.
Passage: Second-generation antihistamines cross the blood--brain barrier to a much lower degree than the first-generation antihistamines. Their main benefit is they primarily affect peripheral histamine receptors and therefore are less sedating. However, high doses can still induce drowsiness through acting on the central nervous system. Some second-generation antihistamines, notably cetirizine, can interact with CNS psychoactive drugs such as bupropion and benzodiazepines.

Question: do second generation antihistamines cross the blood brain barrier?

Is the answer True or False? Respond with only "True" or "False" and no additional text.
True
True. However, they do so to a much lower degree than first-generation antihistamines.