Provide your best answer for the following question. Give ONLY the answer, no other words or explanation.
For example:

Answer: <most likely answer, as short as possible; not a complete sentence, just the answer!>.

The question is: Chromosome mutations involve the deletion or duplication of many genes. The effects of chromosome mutations are often much greater than mutations within a single gene, because chromosome mutations
can cause abnormal development of the offspring.
alter gene expression at a larger scale.