Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.

Example pair: 
Instruction: Hello. Please read over the information below and create a summary of the following:

The story is set around the turn of the twentieth century, during the British era of colonialism. It begins with Colonel Masters (John Williams, excellent as always portraying a classic stiff-upper-lip British gent) returning home after some time away. He is greeted by his housekeeper, Miss Danton (Shani Wallis) who asks how long he’ll be home to which he replies “that will depend on the whims of the general staff at the colonial office.”

His young niece Monica also lives here and she greets her uncle and excitedly tells him that she has a new doll, which she has with her. When Col. Masters’ eyes glance downward to the doll, his expression changes to one of shock and fear.  When we see the doll, the viewer’s face may do the same, even before hearing the doll’s back story.
Response: At the beginning of the 20th century, British colonial Colonel Masters returns home to his housekeeper, Miss Danton. Monica, his young niece, also lives at the house with Miss Danton and is happy to see her uncle. But when she shows him her new doll, his reaction changes to one of horror and alarm. 

Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context. 

Store the generated pairs in valid JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance: 

{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]} 

Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.

Read the following text and summarize the key events in a clear and concise manner:

In the late 1800s, a young woman named Elizabeth defied societal conventions by pursuing a career in medicine. Born into a wealthy family, Elizabeth was expected to marry well and lead a life of leisure. However, she was fascinated by science from a young age and dreamed of becoming a doctor. Against the wishes of her parents, Elizabeth enrolled in one of the few medical schools that accepted female students at the time. Her studies were grueling, and she faced discrimination and skepticism from her male peers and professors. Undeterred, Elizabeth excelled in her coursework and eventually became one of the first female doctors in her country. She went on to open a clinic in a poor neighborhood, providing affordable healthcare to those who needed it most. Elizabeth's determination and pioneering spirit paved the way for future generations of women in medicine.
user
In the late 1800s, Elizabeth defied societal expectations for wealthy women by pursuing a career in medicine. Despite facing discrimination and opposition, even from her own family, she persevered through grueling studies to become one of the first female doctors in her country. Elizabeth then opened a clinic in an underprivileged area, providing affordable healthcare and blazing a trail for future women in the medical field.
assistant