Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.

Example pair: 
Instruction: Please summarize how Asian American and Pacific Islander Heritage Month was started based on the text below: 

History
A former congressional staffer in the 1970s, Jeanie Jew, first approached Representative Frank Horton with the idea of designating a month to recognize Asian Pacific Americans, following the bicentennial celebrations.[19] In June 1977, Representatives Horton, and Norman Y. Mineta, introduced a United States House of Representatives resolution to proclaim the first ten days of May as Asian-Pacific Heritage Week.[20][21] A similar bill was introduced in the Senate a month later by Daniel Inouye and Spark Matsunaga.[20][22]

The proposed resolutions sought that May be designated for two reasons. For on May 7, 1843, the first Japanese immigrant arrived in the United States.[23][24][25] More than two decades later, on May 10, 1869, the golden spike was driven into the first transcontinental railroad, which was completed using Chinese labor.[23][24][26]

President Jimmy Carter signed a joint resolution for the celebration on October 5, 1978.[20]

On May 1, 2009, President Barack Obama signed Proclamation 8369, recognizing the month of May as Asian American and Pacific Islander Heritage Month.[1][27]
Response: A former congressional staffer with the idea approached a representative about it in the 1970s. In 1977, a resolution was introduced in the House and the Senate, and the President signed it in 1978. However, that resolution was only for the first ten days of May. It wasn't until 2009 that the whole month of May was named Asian American and Pacific Islander Heritage Month.

Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context. 

Store the generated pairs in valid JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance: 

{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]} 

Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.

Summarize the key points about the role of the placebo effect in clinical trials based on the text below:

The placebo effect is an important factor that must be accounted for in clinical trials testing new drugs or treatments. A placebo is an inactive substance or treatment that has no direct therapeutic effect, but can produce perceived benefits due to psychological factors. In clinical trials, one group receives the actual treatment being studied while another group receives an identical placebo. This allows researchers to distinguish the effects of the treatment from the placebo effect. The placebo effect demonstrates the power of the mind to influence physical experiences and health outcomes. While placebos themselves don't directly cause changes, a person's expectations and beliefs can modulate factors like pain perception, anxiety, and even some physiological processes. Accounting for the placebo effect helps ensure that only effective treatments make it to market.
user
Clinical trials include a placebo group to account for the placebo effect, where people experience perceived benefits from an inactive treatment due to psychological factors like expectations and beliefs. Comparing the placebo group to the treatment group allows researchers to separate the actual effects of the treatment from those caused by the placebo effect's influence on factors like pain and anxiety. Properly accounting for the placebo effect helps ensure only genuinely effective treatments get approved.
assistant