Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.

Example pair: 
Instruction: Can you give me a summary of why it is harmful to use weight loss drugs?

Here is the article:

Weight loss drugs have soared in popularity in the past year, helping some lose dramatic amounts of weight — but not all that weight is fat. 

Some of that is actually lean mass, which is everything in the body that isn’t fat, including your bones, organs and, importantly, muscle. 

“When we look at weight reduction from any intervention, about one-third of the weight we lose tends to be lean mass, and that can be problematic,” said Dr. Jaime Almandoz, an associate professor of internal medicine in the Division of Endocrinology at UT Southwestern Medical Center in Dallas. That lean mass loss is generally from muscle. “Lean mass is healthier and associated with better metabolism, so when we lose lean mass, we may lose some of that function.”

The more muscle mass a person has, the better the resting metabolic rate, or the number of calories a person burns at rest. When a person loses muscle mass, the resting metabolic rate decreases, too.
Response: Utilizing weight-loss drugs can be harmful. They help an individual lose weight quickly, but some of that weight comes from healthy lean body mass. Lean body mass is important because it helps bolster metabolism, which is how many calories the body burns at rest.

Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context. 

Store the generated pairs in valid JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance: 

{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]} 

Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.

Summarize the following text about the challenges of summarizing multimedia content:

While summarizing text-based materials is a well-established practice, the rise of multimedia content has introduced new challenges in the realm of summarization. Unlike written texts, multimedia content such as videos, podcasts, and interactive presentations often incorporate multiple modalities, including audio, visuals, and interactive elements. Summarizing these diverse formats requires the ability to synthesize information from various channels simultaneously. For example, summarizing a video might necessitate analyzing not only the spoken dialogue but also the visual cues, graphics, and on-screen text. This multifaceted approach can be cognitively demanding and may require specialized skills or tools. Furthermore, multimedia content often lacks a linear structure, making it more challenging to identify and extract the most salient points. Additionally, the dynamic nature of multimedia can make it difficult to capture the nuances and contextual cues that contribute to the overall meaning and impact of the content.
user
Summarizing multimedia content presents unique challenges due to the incorporation of multiple modalities, such as audio, visuals, and interactive elements. It requires synthesizing information from various channels simultaneously, analyzing both spoken dialogue and visual cues. Identifying salient points is more complex due to the non-linear nature of multimedia and the need to capture nuances and contextual cues that contribute to the overall meaning.
assistant