Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.

Example pair: 
Instruction: Can you give me a summary of why it is harmful to use weight loss drugs?

Here is the article:

Weight loss drugs have soared in popularity in the past year, helping some lose dramatic amounts of weight — but not all that weight is fat. 

Some of that is actually lean mass, which is everything in the body that isn’t fat, including your bones, organs and, importantly, muscle. 

“When we look at weight reduction from any intervention, about one-third of the weight we lose tends to be lean mass, and that can be problematic,” said Dr. Jaime Almandoz, an associate professor of internal medicine in the Division of Endocrinology at UT Southwestern Medical Center in Dallas. That lean mass loss is generally from muscle. “Lean mass is healthier and associated with better metabolism, so when we lose lean mass, we may lose some of that function.”

The more muscle mass a person has, the better the resting metabolic rate, or the number of calories a person burns at rest. When a person loses muscle mass, the resting metabolic rate decreases, too.
Response: Utilizing weight-loss drugs can be harmful. They help an individual lose weight quickly, but some of that weight comes from healthy lean body mass. Lean body mass is important because it helps bolster metabolism, which is how many calories the body burns at rest.

Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context. 

Store the generated pairs in valid JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance: 

{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]} 

Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.

Summarize the following instructions on how to effectively summarize a research paper: To effectively summarize a research paper, start by thoroughly reading and understanding the paper's content, including its purpose, methodology, findings, and conclusions. Identify the paper's main thesis or central argument, as well as the key supporting points and evidence presented. In your summary, begin with a clear and concise statement of the paper's main idea or thesis. Then, briefly outline the major sections or components of the paper, highlighting the most significant points, findings, or arguments within each section. Avoid including minor details, examples, or extensive background information unless they are crucial to understanding the paper's main focus. Use your own words to paraphrase the key ideas, and be objective in your representation of the paper's content. Finally, ensure that your summary is well-organized, coherent, and accurately captures the essence of the research paper.
user
The given instructions outline the process of effectively summarizing a research paper. The key steps involve: thoroughly reading and understanding the paper's purpose, methodology, findings, and conclusions; identifying the main thesis or central argument, as well as key supporting points and evidence; clearly stating the main idea or thesis in the summary; briefly outlining major sections or components, highlighting significant points, findings, or arguments; avoiding minor details unless crucial; paraphrasing key ideas in your own words; maintaining objectivity; and ensuring a well-organized, coherent summary that accurately captures the essence of the research paper.
assistant