The basal ganglia balances excitation and inhibition of the thalamo-cortical circuit involved in motor execution; this balance is thought to be altered in task-specific dystonias due to reduced GABAergic metabolism and dopaminergic receptor binding--this leads to excessive motor cortical excitation.
This balance is thought to be altered in task-specific dystonias due to reduced GABAergic metabolism and dopaminergic receptor binding--this leads to excessive motor cortical excitation. The basal ganglia balances excitation and inhibition of the thalamo-cortical circuit involved in motor execution.
The basal ganglia balances excitation and inhibition of the thalamo-cortical circuit involved in motor execution. This balance is thought to be altered in task-specific dystonias due to reduced GABAergic metabolism and dopaminergic receptor binding--this leads to excessive motor cortical excitation.
The basal ganglia balances excitation and inhibition of the thalamo-cortical circuit involved in motor execution. This balance is thought to be altered in task-specific dystonias due to reduced GABAergic metabolism and dopaminergic receptor binding--this leads to excessive motor cortical excitation.