The process of negative selection in the thymus guarantees that virtually all T cells have very weak affinity for self-antigens, the study of these lymphocytes in autoimmune diseases and cancer has been difficult until the fairly recent introduction of MHC multimers.
Therefore, the study of these lymphocytes in autoimmune diseases and cancer has been difficult, until the fairly recent introduction of MHC multimers. The process of negative selection in the thymus guarantees that virtually all T cells have very weak affinity for self-antigens.
The process of negative selection in the thymus guarantees that virtually all T cells have very weak affinity for self-antigens. Therefore, the study of these lymphocytes in autoimmune diseases and cancer has been difficult, until the fairly recent introduction of MHC multimers.
The process of negative selection in the thymus guarantees that virtually all T cells have very weak affinity for self-antigens. Therefore, the study of these lymphocytes in autoimmune diseases and cancer has been difficult, until the fairly recent introduction of MHC multimers.