In healthy mammalian cells, the majority of Bax is found in the cytosol, but upon initiation of apoptotic signaling, Bid undergoes a conformation shift, and inserts into organelle membranes, primarily the outer mitochondrial membrane.
However, upon the initiation of apoptotic signaling, BAX undergoes a conformation shift, and inserts into organelle membranes, primarily the outer mitochondrial membrane. In healthy mammalian cells, the majority of BAX is found in the cytosol.
In healthy mammalian cells, the majority of BAX is found in the cytosol. However, upon the initiation of apoptotic signaling, BAX undergoes a conformation shift, and inserts into organelle membranes, primarily the outer mitochondrial membrane.
In healthy mammalian cells, the majority of BAX is found in the cytosol. However, upon the initiation of apoptotic signaling, BAX undergoes a conformation shift, and inserts into organelle membranes, primarily the outer mitochondrial membrane.