Their binding depends on a correct fucosylation of cell surface glycoproteins and lack thereof leads to leukocytosis and increase sensitivity to infections as seen in SLC35C1-CDG (CDG-IIc); caused by a GDP-fucose (Fuc) transporter deficiency.
Lack thereof leads to leukocytosis and increase sensitivity to infections as seen in SLC35C1-CDG (CDG-IIc); caused by a GDP-fucose (Fuc) transporter deficiency. Their binding depends on a correct fucosylation of cell surface glycoproteins.
Their binding depends on a correct fucosylation of cell surface glycoproteins. Lack thereof leads to leukocytosis and increase sensitivity to infections as seen in SLC35C1-CDG (CDG-IIc); caused by a GDP-fucose (Fuc) transporter deficiency.
Their binding depends on a correct fucosylation of cell surface glycoproteins. Lack thereof leads to leukocytosis and increase sensitivity to infections as seen in SLC35C1-CDG (CDG-IIc); caused by a GDP-fucose (Fuc) transporter deficiency.